Partial mastectomy: pathologic findings and prognosis. Academic Article uri icon

Overview

abstract

  • In an attempt to identify patients best suited for limited surgery as well as those at risk for recurrence and increased mortality, the authors reviewed the clinical and pathologic features of 130 patients who had undergone partial mastectomy as primary treatment for breast cancer (adjuvant therapy was administered only after disease recurrence). Patients were followed up for 57 to 128 months (mean, 85 months). Univariate and multivariate analyses were performed for the entire group and repeated for the large subgroup of patients with infiltrating ductal cancer, not otherwise specified. Three features were independently significant in correlating with poor survival and/or tumor recurrence: lymph node metastasis, mitotic rate, and nuclear atypia. Combinations of these factors further separated survivors from non-survivors. These prognostically significant pathologic features may be helpful in both selecting patients for partial mastectomy and identifying those who may require adjuvant therapy.

publication date

  • August 1, 1986

Research

keywords

  • Breast Neoplasms
  • Mastectomy

Identity

Scopus Document Identifier

  • 0022517565

Digital Object Identifier (DOI)

  • 10.1016/s0046-8177(86)80202-7

PubMed ID

  • 3733070

Additional Document Info

volume

  • 17

issue

  • 8