Effects of kinins on the isolated perfused rat kidney and evidence for the presence of renal B1 receptors. Academic Article uri icon

Overview

abstract

  • The kinins, particularly lysyl-bradykinin (LBK), have a bimodal effect on the vasculature of isolated rat kidney. The vasorelaxant but not the vasoconstrictor effect of LBK seems to be mediated by prostaglandins. The vasoconstrictor action of LBK can be blocked by (L-Leu)8-des-Arg9-BK indicating that the rat kidney vasculature has B1 kinin-receptor which mediates the effects of kinins and/or their C-terminal metabolites.

publication date

  • January 1, 1986

Research

keywords

  • Bradykinin
  • Kidney

Identity

Scopus Document Identifier

  • 0022991827

PubMed ID

  • 3812094

Additional Document Info

volume

  • 198 Pt A