Dynamics of Immune Reconstitution and Impact on Outcomes across CAR-T Cell Products in Large B-cell Lymphoma. Academic Article uri icon

Overview

abstract

  • This study reveals differences in IR patterns after CAR-T therapy in patients with large B-cell lymphoma, with early NK cell recovery emerging as a key predictor of survival. These findings provide potential future avenues of research for improving patient outcomes and tailoring post-therapy management strategies to mitigate relapse risk.

publication date

  • March 4, 2025

Research

keywords

  • Immune Reconstitution
  • Immunotherapy, Adoptive
  • Lymphoma, Large B-Cell, Diffuse
  • Receptors, Chimeric Antigen

Identity

PubMed Central ID

  • PMC11876948

Scopus Document Identifier

  • 86000672645

Digital Object Identifier (DOI)

  • 10.1158/2643-3230.BCD-24-0163

PubMed ID

  • 39666878

Additional Document Info

volume

  • 6

issue

  • 2