Dementia with bilateral medial temporal lobe ischemia. uri icon

Overview

abstract

  • Neuropathologic examination of two patients with dementia showed chronic bilateral medial temporal lobe ischemic damage that included the hippocampus (particularly the CA-1 region), subiculum, and amygdala. Both patients had several myocardial infarctions, and the relatively circumscribed cerebral injury may have resulted from one or more episodes of global hypoxic ischemia. Focal hippocampal injury has been associated with amnesia. The additional damage to medial temporal lobe structures may have caused the dementia.

publication date

  • December 1, 1985

Research

keywords

  • Brain
  • Dementia
  • Ischemic Attack, Transient
  • Myocardial Infarction

Identity

Scopus Document Identifier

  • 0022367806

Digital Object Identifier (DOI)

  • 10.1212/wnl.35.12.1793

PubMed ID

  • 4069376

Additional Document Info

volume

  • 35

issue

  • 12