Vaccination as a strategy for Chlamydia trachomatis control: a global mathematical modeling analysis.

Overview

BACKGROUND: Chlamydia trachomatis (CT) is among the most common sexually transmitted infections and is associated with substantial health and economic burdens. Vaccination may offer a promising strategy for its global control. METHODS: VE RESULTS: VE CONCLUSIONS: Vaccination against CT can substantially reduce global infection burden, even with moderate efficacy. Impact is enhanced by targeted strategies, with adolescent vaccination aiding long-term control and catch-up programs ensuring immediate benefit. These findings highlight the urgency of vaccine development and integration into public health efforts.