Contemporary Treatment Strategies in Pulmonary Hypertension: A Clinician's Guide. Review uri icon

Overview

abstract

  • Pulmonary hypertension (PH) is a complex condition characterized by pulmonary vasculopathy and progressive right ventricular dysfunction. Recent advances have reshaped PH management, including refined risk stratification, improved patient phenotyping, and the discovery of novel therapeutics. In alignment with the recommendations of the Seventh World Symposium on Pulmonary Hypertension, we summarize updated treatment strategies and emerging therapies, such as sotatercept, while acknowledging research gaps and areas of clinical equipoise. This practical, evidence-based review explores treatment across all groups of PH to inform clinical decision-making, improve long-term patient outcomes, and address both current and future challenges in PH management.

publication date

  • October 20, 2025

Identity

Digital Object Identifier (DOI)

  • 10.1146/annurev-med-042623-013335

PubMed ID

  • 41115170