Clinician- and Geographic-level Variation in Utilization of Sacral Neuromodulation and OnabotulinumtoxinA Injections Among Medicare Beneficiaries With Overactive Bladder. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: To evaluate clinician- and geographic-level variation in utilization of sacral neuromodulation (SNM) and onabotulinumtoxinA injections as index treatment for overactive bladder (OAB) among United States Medicare beneficiaries. METHODS: This is a cross-sectional study of a 100% sample of fee-for-service Medicare beneficiaries undergoing first-time SNM test procedures or onabotulinumtoxinA injections from 2014-2016. The primary outcomes were clinician- and geographic-level variation in utilization of SNM or onabotulinumtoxinA injections. Secondary outcomes included variation in use of SNM test procedures (percutaneous nerve evaluation [PNE] and stage 1 permanent tined lead placement [stage 1]). Geographic region was defined using hospital referral regions (HRRs). Mixed-effect logistic regression models were used to calculate the median odds ratio (MOR) for clinician and HRR (higher MOR = greater variability between groups) and to identify individual-level predictors of utilization. RESULTS: Overall, 48,580 Medicare beneficiaries underwent SNM (47.1%) or onabotulinumtoxinA injections (52.9%) during the study period. There was a considerable amount of variation according to clinician and HRR, which were more influential than patient-level characteristics in the type of procedure received. The adjusted MOR for SNM versus onabotulinumtoxinA injections was 33.1 for clinician and 4.24 for HRR. For stage 1 versus PNE, the MOR was 13.12 for clinician and 2.44 for HRR. CONCLUSION: Among Medicare beneficiaries undergoing first-time SNM or onabotulinumtoxinA injections, there was considerable variation according to performing clinician and geographic region. These findings suggest that non-clinical variables-who a patient sees and where they live-are significant drivers of minimally invasive OAB therapy utilization in the United States.

authors

  • Dreyfuss, Leo
  • Wang, Lufan
  • Nik-Ahd, Farnoosh
  • Shatkin-Margolis, Abigail
  • Covinsky, Kenneth
  • John Boscardin, W
  • Suskind, Anne M

publication date

  • November 4, 2025

Research

keywords

  • Botulinum Toxins, Type A
  • Electric Stimulation Therapy
  • Neuromuscular Agents
  • Practice Patterns, Physicians'
  • Urinary Bladder, Overactive

Identity

PubMed Central ID

  • PMC12820582

Scopus Document Identifier

  • 105025009621

Digital Object Identifier (DOI)

  • 10.1016/j.urology.2025.10.040

PubMed ID

  • 41197836

Additional Document Info

volume

  • 208