Envisioning a Multidisciplinary HBV Cure Research Agenda.

Overview

PURPOSE OF REVIEW: We examine the current understanding of the multidisciplinary aspects of hepatitis B cure research, such as socio-behavioral sciences, ethics, community engagement, and translational and implementation science. RECENT FINDINGS: The peer-reviewed literature on the multi-disciplinary aspects of HBV cure research is gradually expanding, although several areas still require attention. These deficiencies include: the acceptability of HBV treatment discontinuations, HBV-related stigma, the impact of co-infections (e.g., HIV), and the translation of discoveries to resource-limited settings. This review highlights the importance of a multidisciplinary framework that bridges socio-behavioral sciences, ethics, community engagement, and translational and implementation science to help ensure the development of an effective, acceptable, scalable and equitable HBV cure.