Is lower extremity joint replacement surgery associated with weight loss? An institutional retrospective study of 36,993 cases. Academic Article uri icon

Overview

abstract

  • Total joint arthroplasty (TJA), including total hip (THA) and knee arthroplasty (TKA), improves mobility and quality of life. While often assumed to promote weight loss, evidence on long-term weight change remains mixed. In this large retrospective cohort study of 36,993 adults undergoing primary TJA at a tertiary academic center (2016-2021), we characterize weight and BMI changes following TJA, and identify postoperative weight patterns across preoperative BMI subgroups. BMI and weight were recorded at surgery and at routine 3-month postoperative intervals. Patients were stratified by baseline BMI to assess weight trajectories across subgroups (<25, 25 to <30, 30 to <35, 35 to <40, ≥40 kg/m²). Both THA and TKA patients demonstrated modest short-term BMI reductions within 1-3 months (-0.55% and -1.15%, respectively). However, by 13-15 months, net BMI change approached baseline for THA (-0.09%) and TKA (-0.65%). Patients with BMI ≥ 40 kg/m² exhibited the greatest initial loss (-1.30%) but later rebounded above baseline (+0.21%). Across all BMI groups, absolute changes in BMI and body weight were minimal, with an inflection toward weight regain at 7-9 months. Thus, TJA does not necessarily drive clinically meaningful or lasting weight loss, underscoring the importance of integrated perioperative weight-management strategies, particularly for patients with obesity.

publication date

  • January 3, 2026

Identity

Digital Object Identifier (DOI)

  • 10.1038/s41366-025-02014-x

PubMed ID

  • 41484351