Lymphocyte transformation induced by autologous cells. II. Stimulation by mitogen-induced lymphoblasts. Academic Article uri icon

Overview

abstract

  • Lymphocytes incubated with phytohemagglutinin or concanavalin A develop the capacity to stimulate autologous lymphocyte transformation. This is not attributable to residual mitogen contaminating the lymphoblastic cell preparation as: (a) the dissociation of mitogen from the lymphoblastic cell preparation increases the degree of stimulation observed and (b) the kinetics of lymphocyte transformation stimulated by phytohemagglutinin-induced lymphoblasts is different from that stimulated by phytohemagglutinin. The appearance of the stimulatory determinants on lymphocytes exposed to phytohemagglutinin precedes morphological transformation.

publication date

  • March 1, 1973

Research

keywords

  • Lectins
  • Lymphocyte Activation
  • Lymphocytes

Identity

PubMed Central ID

  • PMC2139376

Scopus Document Identifier

  • 0015592449

PubMed ID

  • 4689338

Additional Document Info

volume

  • 137

issue

  • 3