Studies on the syngeneic mixed lymphocyte reaction. III. Development of a monoclonal antibody with specificity for autoreactive T cells. Academic Article uri icon

Overview

abstract

  • Monoclonal antibodies with specificity for autoreactive murine T cells have been developed. These antibodies inhibit proliferative response of splenic T cells activated by syngeneic spleen cells. These antibodies have no effect on the proliferative response of T cells activated by allogeneic spleen cells or PHA. The number of splenic T cells that react with these monoclonal antibodies is comparable in several normal mouse strains.

publication date

  • October 1, 1983

Research

keywords

  • Antibodies, Monoclonal
  • Antibody Specificity
  • Lymphocyte Activation
  • T-Lymphocytes

Identity

PubMed Central ID

  • PMC2187364

Scopus Document Identifier

  • 0020528642

PubMed ID

  • 6225824

Additional Document Info

volume

  • 158

issue

  • 4