Cytokines and the chronic inflammation of rheumatic disease. II. The presence of interleukin-2 in synovial fluids. Academic Article uri icon

Overview

abstract

  • Sera and synovial fluids from patients with a variety of rheumatic diseases were assayed for interleukin-2 (IL-2) activity in a system utilizing the proliferative response of cultured human phytohaemagglutinin (PHA) T cell blasts. The synovial fluids from 14 rheumatoid arthritis, eight ankylosing spondylitis, three psoriatic arthritis and 11 osteoarthritis patients, all showed IL-2 activity. The amounts of IL-2 present in the fluids from different diseases were compared and ranged from 4.2 to 140.0 units/ml.

publication date

  • November 1, 1984

Research

keywords

  • Interleukin-2
  • Rheumatic Diseases
  • Synovial Fluid

Identity

PubMed Central ID

  • PMC1577049

Scopus Document Identifier

  • 0021716883

PubMed ID

  • 6333945

Additional Document Info

volume

  • 58

issue

  • 2