Randomized trial of standard therapy with or without poly I:C in patients with superficial bladder cancer. Academic Article uri icon

Overview

abstract

  • Thirty-two patients with superficial urinary bladder tumors were stratified for four variables and randomized after complete transurethral resection and/or fulguration of tumor to receive standard therapy with or without intravenous Poly I:C. Cystoscopies were performed at three- to four-month intervals for up to 48 months. While there was no statistically significant difference in the tumor recurrence rates in the two groups during the first year, a significant increase (P = 0.003) in survival at four years was observed between the Poly I:C group and the control group. The difficulties in evaluating the efficacy of anti-neoplastic agents in the treatment of superficial bladder tumors are discussed.

publication date

  • November 15, 1981

Research

keywords

  • Poly I-C
  • Urinary Bladder Neoplasms

Identity

Scopus Document Identifier

  • 0019785549

PubMed ID

  • 7028242

Additional Document Info

volume

  • 48

issue

  • 10