Human astrocyte production of tumour necrosis factor-alpha, interleukin-1 beta, and interleukin-6 following exposure to lipopolysaccharide endotoxin. Academic Article uri icon

Overview

abstract

  • The cytokines, tumour necrosis factor (TNF)-alpha, interleukin (IL)-1 beta, and IL-6, have been found in the human central nervous system. Recent studies have demonstrated that murine astrocytes produce these cytokines when induced with lipopolysaccharide endotoxin (LPS). The present study investigates the kinetics of TNF-alpha, IL-1 beta, and IL-6 production by normal adult human astrocytes when exposed to LPS.

publication date

  • April 1, 1993

Research

keywords

  • Astrocytes
  • Endotoxins
  • Interleukin-1
  • Interleukin-6
  • Lipopolysaccharides
  • Tumor Necrosis Factor-alpha

Identity

Scopus Document Identifier

  • 0027161306

PubMed ID

  • 8099204

Additional Document Info

volume

  • 15

issue

  • 2