The effect of a cyclooxygenase inhibitor on the in vivo polymorphonuclear leukocyte migration to Pseudomonas aeruginosa peptide chemotactins. Academic Article uri icon

Overview

abstract

  • Pseudomonas aeruginosa chemotactic peptides (PAPCs) induced migration of polymorphonuclear leukocytes (PMNL) into the lungs when administered by the aerosol route. Migration of PMNL into the lungs and total protein content of lung lavage fluids in response to PAPCs aerosol challenge, and mortality from lethal challenge with P. aeruginosa were decreased by piroxicam treatment.

publication date

  • September 1, 1993

Research

keywords

  • Chemotactic Factors
  • Chemotaxis, Leukocyte
  • Cyclooxygenase Inhibitors
  • Neutrophils
  • Piroxicam
  • Pseudomonas aeruginosa

Identity

Scopus Document Identifier

  • 0027729426

Digital Object Identifier (DOI)

  • 10.1007/BF01976758

PubMed ID

  • 8147264

Additional Document Info

volume

  • 40

issue

  • 1-2