Soft-tissue reconstruction following extravasation of chemotherapeutic agents. Review uri icon

Overview

abstract

  • The incidence of chemotherapeutic extravasation injuries ranges from 0.5% to 6%. Chronicity and an indolent course are prominent characteristics of such wounds, as are severe pain and ulceration with no tendency to spontaneous healing. Prevention is the best treatment. Aggressive surgical debridement is recommended for patients with persistent pain or ulceration. Whirlpool therapy, wet-to-dry dressing changes, and a vigorous physical therapy program are all helpful. Soft-tissue coverage can be obtained by skin grafting, delayed flaps, various local muscle or fasciocutaneous flaps, or by free tissue transfer.

publication date

  • October 1, 1996

Research

keywords

  • Antineoplastic Agents
  • Extravasation of Diagnostic and Therapeutic Materials
  • Skin Transplantation
  • Surgical Flaps

Identity

Scopus Document Identifier

  • 0029852226

PubMed ID

  • 8899947

Additional Document Info

volume

  • 5

issue

  • 4