Treatment of bilateral cytomegalovirus retinitis with sustained-release ganciclovir implants in a child. uri icon

Overview

abstract

  • PURPOSE: To report treatment of bilateral cytomegalovirus (CMV) retinitis in an 11-year-old girl with acquired immunodeficiency syndrome (AIDS). METHOD: Case report describing the use of intravitreal ganciclovir sustained-release devices to treat CMV retinitis, involving zones 1 through 3, which progressed despite single and combination intravenous therapy with ganciclovir and foscarnet. RESULTS: Stabilization with no active CMV retinitis was achieved after bilateral implantation of intravitreal sustained-release ganciclovir devices. There was no reactivation of the retinitis during the 5 months of follow-up. CONCLUSION: Sustained-release ganciclovir implants can be used to achieve local control of CMV retinitis in the pediatric patient.

publication date

  • November 1, 1996

Research

keywords

  • AIDS-Related Opportunistic Infections
  • Antiviral Agents
  • Cytomegalovirus Retinitis
  • Ganciclovir

Identity

Scopus Document Identifier

  • 0029851584

PubMed ID

  • 8909217

Additional Document Info

volume

  • 122

issue

  • 5