Improved detection of recurrent bladder cancer using the Bard BTA stat Test. Academic Article uri icon

Overview

abstract

  • OBJECTIVES: To evaluate the BTA stat Test in the detection of recurrent bladder cancer. METHODS: Sensitivity and specificity were determined using frozen voided urine samples from patients with recurrent bladder cancer, volunteers, patients with nonurologic conditions, and patients with a history of bladder cancer but free of disease. Results of cytology and the original BTA Test were compared with the sensitivity of the BTA stat Test in a large subgroup of the patients with cancer. RESULTS: The BTA stat Test detected 147 (67%) of 220 recurrent cancers. For those urine samples with previous cytologic and BTA Test results available, cytology had a sensitivity of 23%, the BTA Test 44%, and the BTA stat Test 58% for detection of recurrent cancer (P < 0.001, stat versus cytology). The specificity of the BTA stat Test was 72% for benign genitourinary disease and 95% in healthy volunteers. CONCLUSIONS: The BTA stat Test has high sensitivity and is significantly superior to voided urine cytologic analysis in the detection of recurrent bladder cancer.

publication date

  • September 1, 1997

Research

keywords

  • Antigens, Neoplasm
  • Neoplasm Recurrence, Local
  • Urinary Bladder Neoplasms

Identity

Scopus Document Identifier

  • 0030821841

PubMed ID

  • 9301696

Additional Document Info

volume

  • 50

issue

  • 3