Subclavian artery pseudoaneurysm in type IV Ehlers-Danlos syndrome. uri icon

Overview

abstract

  • We report case of a subclavian artery pseudoaneurysm in a patient with type IV Ehlers-Danlos Syndrome. A 16-year-old boy underwent successful repair of a subclavian artery pseudoaneurysm that occurred after a cervical hyperextension injury. Subsequent workup included skin biopsy and fibroblast culture, which were consistent with a diagnosis of type IV Ehlers-Danlos Syndrome. This condition is a dominantly inherited connective tissue disorder, which in this patient was found to be caused by a spontaneous point mutation in the COL3A1 gene that encodes the chains of type III procollagen. The clinical, genetic, and molecular characteristics of type IV Ehlers-Danlos Syndrome are briefly reviewed.

publication date

  • March 1, 1998

Research

keywords

  • Aneurysm, False
  • Ehlers-Danlos Syndrome
  • Neck Injuries
  • Subclavian Artery
  • Wrestling

Identity

Scopus Document Identifier

  • 0031966849

PubMed ID

  • 9546243

Additional Document Info

volume

  • 27

issue

  • 3