Culture substrate-specific expression of P2Y2 receptors in distal lung epithelial cells isolated from foetal rats. Academic Article uri icon

Overview

abstract

  • ATP and UTP did not evoke [Ca2+]i signals in rat foetal lung epithelial cells grown on glass but elicited clear responses in cells grown into functionally polarised epithelia on permeable supports. Moreover, P2Y2 receptor mRNA could not be detected in cells on glass by the polymerase chain reaction but this mRNA species was clearly expressed by polarised cells. P2Y2 receptor expression thus appears to be a feature of the polarised phenotype.

publication date

  • July 1, 1998

Research

keywords

  • Epithelial Cells
  • Lung
  • Receptors, Purinergic P2

Identity

PubMed Central ID

  • PMC1565477

Scopus Document Identifier

  • 0031808677

PubMed ID

  • 9692767

Additional Document Info

volume

  • 124

issue

  • 5