selected publications
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Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis.
International journal of cancer.
2023
Academic Article
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Times cited: 8 -
The Critical Role of AMPKα1 in Regulating Autophagy and Mitochondrial Respiration in IL-15-Stimulated mTORC1Weak Signal-Induced T Cell Memory: An Interplay between Yin (AMPKα1) and Yang (mTORC1) Energy Sensors in T Cell Differentiation.
International journal of molecular sciences.
2022
Academic Article
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Times cited: 11 -
DDX41 is required for cGAS-STING activation against DNA virus infection.
Cell reports.
2022
Academic Article
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Times cited: 72 -
Prosurvival IL-7-Stimulated Weak Strength of mTORC1-S6K Controls T Cell Memory via Transcriptional FOXO1-TCF1-Id3 and Metabolic AMPKα1-ULK1-ATG7 Pathways.
Journal of immunology (Baltimore, Md. : 1950).
2021
Academic Article
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Times cited: 15 -
Distinct roles but cooperative effect of TLR3/9 agonists and PD-1 blockade in converting the immunotolerant microenvironment of irreversible electroporation-ablated tumors.
Cellular & molecular immunology.
2021
Academic Article
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Times cited: 37 -
TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inhibition of primary tumor growth and lung metastasis.
Cellular & molecular immunology.
2018
Academic Article
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Times cited: 57 -
Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways.
Scientific reports.
2018
Academic Article
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Times cited: 76 -
Heterologous human/rat HER2-specific exosome-targeted T cell vaccine stimulates potent humoral and CTL responses leading to enhanced circumvention of HER2 tolerance in double transgenic HLA-A2/HER2 mice.
Vaccine.
2018
Academic Article
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Times cited: 19 - CD8+ memory T-cell inflation renders compromised CD4+ T-cell-dependent CD8+ T-cell immunity via naïve T-cell anergy. ImmunoTargets and therapy. 2017 Academic Article GET IT
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CD40 agonist converting CTL exhaustion via the activation of the mTORC1 pathway enhances PD-1 antagonist action in rescuing exhausted CTLs in chronic infection.
Biochemical and biophysical research communications.
2017
Academic Article
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Times cited: 5 -
Enhanced suppression of polyclonal CD8+25+ regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes.
Journal of leukocyte biology.
2017
Academic Article
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Times cited: 16 -
Immunogenicity and efficacy of a rationally designed vaccine against vascular endothelial growth factor in mouse solid tumor models.
Cancer immunology, immunotherapy : CII.
2016
Academic Article
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Times cited: 16 -
Novel T-cell-based vaccines via arming polyclonal CD4+ T cells with antigen-specific exosomes.
Immunotherapy.
2016
Editorial Article
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Times cited: 3 -
A Rationally Designed TNF-α Epitope-Scaffold Immunogen Induces Sustained Antibody Response and Alleviates Collagen-Induced Arthritis in Mice.
PloS one.
2016
Academic Article
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Times cited: 21 -
Novel exosome-targeted T-cell-based vaccine counteracts T-cell anergy and converts CTL exhaustion in chronic infection via CD40L signaling through the mTORC1 pathway.
Cellular & molecular immunology.
2016
Academic Article
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Times cited: 37 -
IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia.
Cell & bioscience.
2016
Academic Article
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Times cited: 32 -
Potent immunotherapy against well-established thymoma using adoptively transferred transgene IL-6-engineered dendritic cell-stimulated CD8+ T-cells with prolonged survival and enhanced cytotoxicity.
The journal of gene medicine.
2015
Academic Article
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Times cited: 5