selected publications
- Astrocytes in selective vulnerability to neurodegenerative disease. Trends in neurosciences. 2024 Review GET IT
- Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT
- Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production. 2023 GET IT
- Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines. Science advances. 2023 Academic Article GET IT
- Quantitative proteomic analysis reveals apoE4-dependent phosphorylation of the actin-regulating protein VASP. Molecular & cellular proteomics : MCP. 2023 Academic Article GET IT
- Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia. Molecular neurodegeneration. 2022 Academic Article GET IT
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The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production.
Redox biology.
2019
Academic Article
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Times cited: 43 - To be or not to be pink(1): contradictory findings in an animal model for Parkinson's disease. Brain communications. 2019 Academic Article GET IT
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Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function.
Journal of Alzheimer's disease : JAD.
2019
Academic Article
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Times cited: 48 -
Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria.
Methods in molecular biology (Clifton, N.J.).
2018
Article
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Times cited: 3 -
Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons.
eNeuro.
2017
Academic Article
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Times cited: 16 -
Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease.
Neurochemistry international.
2017
Academic Article
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Times cited: 33 -
Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
Cell metabolism.
2016
Academic Article
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Times cited: 154 -
Suppressors of superoxide production from mitochondrial complex III.
Nature chemical biology.
2015
Academic Article
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Times cited: 148 -
Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria.
Free radical biology & medicine.
2014
Academic Article
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Times cited: 45 -
Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase.
PloS one.
2014
Academic Article
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Times cited: 44 -
Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening.
Free radical biology & medicine.
2013
Academic Article
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Times cited: 63 -
Sites of reactive oxygen species generation by mitochondria oxidizing different substrates.
Redox biology.
2013
Academic Article
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Times cited: 450 -
NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.
Neuroscience letters.
2013
Academic Article
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Times cited: 24 -
Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria.
Free radical biology & medicine.
2013
Academic Article
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Times cited: 97 -
A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase.
The Journal of biological chemistry.
2012
Academic Article
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Times cited: 135 -
Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters.
Free radical biology & medicine.
2012
Academic Article
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Times cited: 131 -
Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions.
The Journal of biological chemistry.
2012
Academic Article
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Times cited: 509 -
Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain.
Neuroscience letters.
2012
Academic Article
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Times cited: 18 -
Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling.
Journal of neuroinflammation.
2012
Academic Article
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Times cited: 15 -
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.
Journal of cell science.
2011
Academic Article
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Times cited: 144 -
Impaired mitochondrial trafficking in Huntington's disease.
Biochimica et biophysica acta.
2009
Information Resource
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Times cited: 53 -
Adenosine A(2A) receptor mediates microglial process retraction.
Nature neuroscience.
2009
Academic Article
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Times cited: 280 -
A FRET-based method to study protein thiol oxidation in histological preparations.
Free radical biology & medicine.
2008
Academic Article
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Times cited: 29 -
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.
Human molecular genetics.
2008
Academic Article
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Times cited: 131 -
Sex-dependent effect of BAG1 in ameliorating motor deficits of Huntington disease transgenic mice.
The Journal of biological chemistry.
2008
Academic Article
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Times cited: 25 -
Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice.
The Journal of cell biology.
2008
Academic Article
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Times cited: 146 -
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2008
Academic Article
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Times cited: 339