selected publications
- Pre-treatment metastatic biopsy: a step towards precision oncology for urothelial cancer. Nature reviews. Urology. 2024 Review GET IT
- The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution. Nature. 2024 Academic Article GET IT
- FGFR Inhibition in Urothelial Carcinoma. European urology. 2024 Review GET IT
- Urine Biopsy as Dynamic Biomarker to Enhance Clinical Staging of Bladder Cancer in Radical Cystectomy Candidates. JCO precision oncology. 2024 Academic Article GET IT
- The evolution of metastatic upper tract urothelial carcinoma through genomic-transcriptomic and single-cell protein markers analysis. Nature communications. 2024 Academic Article GET IT
- A combinatorial genetic strategy for exploring complex genotype-phenotype associations in cancer. Nature genetics. 2024 Academic Article GET IT
- A new era in the treatment of urothelial carcinoma. Urologic oncology. 2023 Review GET IT
- Novel Use of Circulating Tumor DNA to Identify Muscle-invasive and Non-organ-confined Upper Tract Urothelial Carcinoma. European urology. 2023 Academic Article GET IT
- Immunotherapy in the Treatment of Localized Genitourinary Cancers. JAMA oncology. 2023 Academic Article GET IT
- A Pilot Study on Hyperthermic Intraperitoneal Chemotherapy after Radical or Partial Cystectomy with Pelvic Lymph Node Dissection for High-risk Muscle-invasive Bladder Cancer. European urology. 2023 Letter GET IT
- Combinatorial genetic strategy accelerates the discovery of cancer genotype-phenotype associations. 2023 GET IT
- Immune Checkpoint Inhibitors and Long-term Survival of Patients With Metastatic Urothelial Cancer. JAMA network open. 2023 Academic Article GET IT
- Circulating and urinary tumour DNA in urothelial carcinoma - upper tract, lower tract and metastatic disease. Nature reviews. Urology. 2023 Review GET IT
- The cytidine deaminase APOBEC3G contributes to cancer mutagenesis and clonal evolution in bladder cancer. Cancer research. 2022 Academic Article GET IT
- Tumor Infiltrating Myeloid Cells Confer de novo Resistance to PD-L1 Blockade through EMT-stromal and Tgf-beta Dependent Mechanisms. Molecular cancer therapeutics. 2022 Academic Article GET IT
- Recurrent exon-deleting activating mutations in AHR act as drivers of urinary tract cancer. Scientific reports. 2022 Academic Article GET IT
- Loss of function mutations in CDKN1A are permissive for APOBEC3-induced mutagenesis in urothelial carcinoma. American journal of cancer research. 2022 Editorial Article GET IT
- The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy. Molecular oncology. 2022 Academic Article GET IT
- Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma. British journal of cancer. 2022 Academic Article GET IT
- Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors. NPJ genomic medicine. 2021 Academic Article GET IT
- Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing. The oncologist. 2021 Academic Article GET IT
- Impact of Use of Antibiotics on Response to Immune Checkpoint Inhibitors and Tumor Microenvironment. American journal of clinical oncology. 2021 Academic Article GET IT
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Spectrum of FGFR2/3 Alterations in Cell-Free DNA of Patients with Advanced Urothelial Carcinoma.
Bladder cancer (Amsterdam, Netherlands).
2021
Academic Article
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Times cited: 5 -
Common germline-somatic variant interactions in advanced urothelial cancer.
Nature communications.
2020
Academic Article
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Times cited: 23 -
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.
Translational oncology.
2020
Academic Article
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Times cited: 9 -
Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers.
Nature communications.
2020
Academic Article
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Times cited: 42 -
Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomes.
Nature reviews. Urology.
2020
Information Resource
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Times cited: 117 -
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
Nature communications.
2020
Academic Article
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Times cited: 129 -
Pan-cancer analysis of whole genomes.
Nature.
2020
Academic Article
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Times cited: 1741 -
The emerging landscape of germline variants in urothelial carcinoma: Implications for genetic testing.
Cancer treatment and research communications.
2020
Academic Article
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Times cited: 2 -
Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer.
JCO precision oncology.
2019
Academic Article
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Times cited: 33 -
Clinical features of neuroendocrine prostate cancer.
European journal of cancer.
2019
Academic Article
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Times cited: 207 -
Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
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Times cited: 12 -
Cancer-Specific Thresholds Adjust for Whole Exome Sequencing-based Tumor Mutational Burden Distribution.
JCO precision oncology.
2019
Academic Article
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Times cited: 27 -
Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling.
Nature communications.
2019
Academic Article
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Times cited: 144 -
Circulating Tumor DNA Alterations in Advanced Urothelial Carcinoma and Association with Clinical Outcomes: A Pilot Study.
European urology oncology.
2019
Academic Article
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Times cited: 13 -
Treatment resistance in urothelial carcinoma: an evolutionary perspective.
Nature reviews. Clinical oncology.
2018
Information Resource
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Times cited: 18 -
Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA.
Cancer.
2018
Academic Article
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Times cited: 78 -
Metastasectomy in older adults with urothelial carcinoma: Population-based analysis of use and outcomes.
Urologic oncology.
2017
Academic Article
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Times cited: 18 -
Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.
JCO precision oncology.
2017
Academic Article
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Times cited: 43 -
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
Cancer discovery.
2017
Academic Article
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Times cited: 723 - Immune-checkpoint blockade in cisplatin-ineligible patients with urothelial cancer. Lancet (London, England). 2016 Article GET IT
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Clonal evolution of chemotherapy-resistant urothelial carcinoma.
Nature genetics.
2016
Academic Article
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Times cited: 230 -
Effect of tumor location on survival in urinary bladder adenocarcinoma: A population-based analysis.
Urologic oncology.
2016
Academic Article
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Times cited: 16 -
Blocking immune checkpoints in prostate, kidney, and urothelial cancer: An overview.
Urologic oncology.
2016
Information Resource
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Times cited: 43 -
Application of next-generation sequencing in gastrointestinal and liver tumors.
Cancer letters.
2016
Information Resource
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Times cited: 3 -
Sacituzumab Govitecan, a Novel Antibody--Drug Conjugate, in Patients With Metastatic Platinum-Resistant Urothelial Carcinoma.
Clinical genitourinary cancer.
2015
Academic Article
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Times cited: 45 -
Radical Cystectomy for Bladder Cancer in Patients With and Without a History of Pelvic Irradiation: Survival Outcomes and Diversion-related Complications.
Urology.
2015
Academic Article
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Times cited: 10 -
Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.
JAMA oncology.
2015
Academic Article
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Times cited: 230 -
Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.
The New England journal of medicine.
2015
Academic Article
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Times cited: 898 -
Recurrence patterns after open and robot-assisted radical cystectomy for bladder cancer.
European urology.
2015
Academic Article
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Times cited: 157 -
Novel molecular targets for urothelial carcinoma.
Expert opinion on therapeutic targets.
2015
Information Resource
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Times cited: 9 -
Myelodysplastic syndromes: toward a risk-adapted treatment approach.
Expert review of hematology.
2013
Information Resource
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Times cited: 19 -
Sustained remission in a patient with myelodysplastic syndrome and a complex karyotype after erythropoiesis-stimulating therapy followed by colonic T-cell lymphoblastic lymphoma.
Leukemia & lymphoma.
2012
Article
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Times cited: 2 -
Dabigatran etexilate: what do hospitalists need to know?.
Journal of hospital medicine.
2011
Information Resource
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Times cited: 5 -
Identifying circulating tumor stem cells that matter: the key to prognostication and therapeutic targeting.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2011
Article
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Times cited: 16 -
Cancer is an ancient disease: the case for better palaeoepidemiological and molecular studies.
Nature reviews. Cancer.
2011
Article
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Times cited: 10 -
Mental nerve neuropathy: frequently overlooked clinical sign of hematologic malignancies.
The American journal of medicine.
2011
Article
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Times cited: 6 -
Targeting hematogenous spread of circulating tumor cells by a chemotactic drug-eluting IVC filter to prevent pulmonary and systemic metastasis.
Medical hypotheses.
2009
Academic Article
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Times cited: 5 -
Update on perioperative bridging in patients on chronic oral anticoagulation.
Expert review of cardiovascular therapy.
2009
Information Resource
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Times cited: 6 -
Gastric Burkitt lymphoma associated with Efalizumab and Helicobacter pylori.
Leukemia & lymphoma.
2009
Article
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Times cited: 1