selected publications
- Integration of dose surface maps and genetic data identifies the lower posterior rectum as a key region for toxicity after prostate cancer radiotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025 Academic Article GET IT
- Sensitivity analysis of dose-response model parameters for the bladder in prostate cancer radiotherapy. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 2025 Academic Article GET IT
- Dose-response mapping of bladder and rectum in prostate cancer patients undergoing radiotherapy with and without baseline toxicity correction. Physics and imaging in radiation oncology. 2025 Academic Article GET IT
- Integrating genetic polymorphisms and clinical data to develop predictive models for skin toxicity in breast cancer radiation therapy. Breast (Edinburgh, Scotland). 2025 Academic Article GET IT
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A Polygenic Risk Score for Late Bladder Toxicity Following Radiotherapy for Non-Metastatic Prostate Cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2025
Academic Article
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Times cited: 2 -
Association of radiation-induced normal tissue toxicity with a high genetic risk for rheumatoid arthritis.
Journal of the National Cancer Institute.
2025
Academic Article
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Times cited: 1 -
Differential Effects of Endocrine Therapy Type on Quality of Life in Older (≥70 Years) Women with Early-Stage Breast Cancer.
Annals of surgical oncology.
2025
Academic Article
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Times cited: 1 -
Age-stratified analysis of health-related quality of life in patients with early-stage breast cancer receiving adjuvant radiation therapy and endocrine therapy.
Journal of geriatric oncology.
2025
Academic Article
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Times cited: 1 - New rectum dose surface mapping methodology to identify rectal subregions associated with toxicities following prostate cancer radiotherapy. Physics and imaging in radiation oncology. 2025 Academic Article GET IT
- Professional-patient discrepancies in assessing lung cancer radiotherapy symptoms: An international multicentre study. Lung cancer (Amsterdam, Netherlands). 2024 Academic Article GET IT
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The Need to Enrich Population Diversity in Radiogenomic Research.
International journal of radiation oncology, biology, physics.
2024
Editorial Article
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Times cited: 1 -
Optimising inter-patient image registration for image-based data mining in breast radiotherapy.
Physics and imaging in radiation oncology.
2024
Academic Article
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Times cited: 1 -
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.
Nature genetics.
2023
Academic Article
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Times cited: 71 -
Large-scale meta-genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types.
JNCI cancer spectrum.
2023
Review
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Times cited: 9 -
Contouring variation affects estimates of normal tissue complication probability for breast fibrosis after radiotherapy.
Breast (Edinburgh, Scotland).
2023
Academic Article
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Times cited: 4 -
Genome-wide association study of treatment-related toxicity two years following radiotherapy for breast cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2023
Academic Article
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Times cited: 7 -
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.
American journal of human genetics.
2023
Academic Article
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Times cited: 11 -
Predicting the germline dependence of hematuria risk in prostate cancer radiotherapy patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2023
Academic Article
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Times cited: 6 -
Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry.
2023
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Times cited: 6 -
Comparing symptom reporting by prostate cancer patients and healthcare professionals in the international multicentre REQUITE study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2022
Academic Article
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Times cited: 3 -
The correlation between pre-treatment symptoms, acute and late toxicity and patient-reported health-related quality of life in non-small cell lung cancer patients: Results of the REQUITE study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2022
Academic Article
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Times cited: 10 -
Treatment time and circadian genotype interact to influence radiotherapy side-effects. A prospective European validation study using the REQUITE cohort.
EBioMedicine.
2022
Academic Article
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Times cited: 13 -
No Association Between Polygenic Risk Scores for Cancer and Development of Radiation Therapy Toxicity.
International journal of radiation oncology, biology, physics.
2022
Academic Article
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Times cited: 3 -
Ocular complications with the use of radium-223: a case series.
Radiation oncology (London, England).
2022
Academic Article
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Times cited: 2 -
Overview of health-related quality of life and toxicity of non-small cell lung cancer patients receiving curative-intent radiotherapy in a real-life setting (the REQUITE study).
Lung cancer (Amsterdam, Netherlands).
2022
Academic Article
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Times cited: 10 -
Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score.
Prostate cancer and prostatic diseases.
2022
Academic Article
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Times cited: 22 -
Factors associated with late local failure and its influence on survival in men undergoing prostate brachytherapy.
Brachytherapy.
2022
Academic Article
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Times cited: 7 -
Use of angiotensin converting enzyme inhibitors is associated with reduced risk of late bladder toxicity following radiotherapy for prostate cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2022
Academic Article
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Times cited: 16 -
Development and Optimization of a Machine-Learning Prediction Model for Acute Desquamation After Breast Radiation Therapy in the Multicenter REQUITE Cohort.
Advances in radiation oncology.
2022
Academic Article
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Times cited: 11 -
A data science approach for early-stage prediction of Patient's susceptibility to acute side effects of advanced radiotherapy.
Computers in biology and medicine.
2021
Academic Article
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Times cited: 6 -
Development of a method for generating SNP interaction-aware polygenic risk scores for radiotherapy toxicity.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2021
Academic Article
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Times cited: 17 -
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
2021
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Times cited: 10 -
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations.
Nature communications.
2021
Academic Article
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Times cited: 44 -
ATM Variants in Breast Cancer: Implications for Breast Radiation Therapy Treatment Recommendations.
International journal of radiation oncology, biology, physics.
2021
Review
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Times cited: 15 -
Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer.
Prostate cancer and prostatic diseases.
2021
Academic Article
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Times cited: 15 -
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
Nature genetics.
2021
Review
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Times cited: 318 -
The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor.
Cancers.
2020
Academic Article
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Times cited: 21 -
External Validation of a Predictive Model for Acute Skin Radiation Toxicity in the REQUITE Breast Cohort.
Frontiers in oncology.
2020
Academic Article
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Times cited: 17 -
A Deep Learning Approach Validates Genetic Risk Factors for Late Toxicity After Prostate Cancer Radiotherapy in a REQUITE Multi-National Cohort.
Frontiers in oncology.
2020
Academic Article
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Times cited: 27 -
I-125 or Pd-103 for brachytherapy boost in men with high-risk prostate cancer: A comparison of survival and morbidity outcomes.
Brachytherapy.
2020
Academic Article
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Times cited: 3 -
Genomics models in radiotherapy: From mechanistic to machine learning.
Medical physics.
2020
Review
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Times cited: 18 -
Survey of Radiation Oncologists to Assess Interest and Potential Use of a Genetic Test Predicting Susceptibility for the Development of Toxicities After Prostate Cancer Radiation Therapy.
Advances in radiation oncology.
2020
Academic Article
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Times cited: 2 -
Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy.
Journal of the National Cancer Institute.
2020
Academic Article
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Times cited: 88 - Use of genomics to balance cure and complications. Nature reviews. Clinical oncology. 2020 Comment GET IT
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Response to Letter to the Editor: Regarding "Teaching Radiation and Cancer Biology to Radiation Oncology Residents: A 40-Year Perspective".
Practical radiation oncology.
2019
Letter
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Times cited: 1 -
Publisher Correction: Shared heritability and functional enrichment across six solid cancers.
2019
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Times cited: 3 -
Teaching Radiation and Cancer Biology to Radiation Oncology Residents: A 40-Year Perspective.
Practical radiation oncology.
2019
Editorial Article
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Times cited: 3 -
The Implications of Genetic Testing on Radiation Therapy Decisions: A Guide for Radiation Oncologists.
International journal of radiation oncology, biology, physics.
2019
Review
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Times cited: 74 -
REQUITE: A prospective multicentre cohort study of patients undergoing radiotherapy for breast, lung or prostate cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2019
Academic Article
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Times cited: 72 -
Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
2019
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Times cited: 10 -
Shared heritability and functional enrichment across six solid cancers.
Nature communications.
2019
Academic Article
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Times cited: 84 -
Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2018
Academic Article
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Times cited: 30 -
Radiogenomic Predictors of Adverse Effects following Charged Particle Therapy.
International journal of particle therapy.
2018
Academic Article
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Times cited: 6 -
Genomics, bio specimens, and other biological data: Current status and future directions.
Medical physics.
2018
Review
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Times cited: 3 -
Machine Learning and Radiogenomics: Lessons Learned and Future Directions.
Frontiers in oncology.
2018
Review
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Times cited: 61 -
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Nature genetics.
2018
Academic Article
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Times cited: 640 -
Radiogenomics: Identification of Genomic Predictors for Radiation Toxicity.
Seminars in radiation oncology.
2017
Review
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Times cited: 43 -
Radiogenomics and radiotherapy response modeling.
Physics in medicine and biology.
2017
Review
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Times cited: 46 -
Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era.
Frontiers in oncology.
2017
Review
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Times cited: 38 -
Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer.
EBioMedicine.
2016
Review
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Times cited: 76 -
Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2016
Review
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Times cited: 105 -
Overview of the American Society for Radiation Oncology-National Institutes of Health-American Association of Physicists in Medicine Workshop 2015: Exploring Opportunities for Radiation Oncology in the Era of Big Data.
International journal of radiation oncology, biology, physics.
2016
Editorial Article
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Times cited: 27 -
Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.
British journal of cancer.
2016
Academic Article
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Times cited: 20 -
Radiogenomics: A systems biology approach to understanding genetic risk factors for radiotherapy toxicity?.
Cancer letters.
2016
Review
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Times cited: 68 -
Prospective Randomized Trial of Prone Accelerated Intensity Modulated Breast Radiation Therapy With a Daily Versus Weekly Boost to the Tumor Bed.
International journal of radiation oncology, biology, physics.
2015
Academic Article
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Times cited: 13 -
How Will Big Data Improve Clinical and Basic Research in Radiation Therapy?.
International journal of radiation oncology, biology, physics.
2015
Editorial Article
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Times cited: 27 -
Lhermitte's Sign following VMAT-Based Head and Neck Radiation-Insights into Mechanism.
PloS one.
2015
Academic Article
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Times cited: 6 -
The Prediction of Radiotherapy Toxicity Using Single Nucleotide Polymorphism-Based Models: A Step Toward Prevention.
Seminars in radiation oncology.
2015
Review
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Times cited: 51 -
XRCC1 Polymorphism Associated With Late Toxicity After Radiation Therapy in Breast Cancer Patients.
International journal of radiation oncology, biology, physics.
2015
Academic Article
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Times cited: 64 -
Radiogenomics: radiobiology enters the era of big data and team science.
International journal of radiation oncology, biology, physics.
2014
Editorial Article
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Times cited: 94 -
Identification of SNPs associated with susceptibility for development of adverse reactions to radiotherapy.
Pharmacogenomics.
2011
Academic Article
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Times cited: 31 -
American Society for Radiation Oncology (ASTRO) survey of radiation biology educators in U.S. and Canadian radiation oncology residency programs.
International journal of radiation oncology, biology, physics.
2009
Academic Article
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Times cited: 18