Rosenstein, Barry

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selected publications

Integration of dose surface maps and genetic data identifies the lower posterior rectum as a key region for toxicity after prostate cancer radiotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025 Academic Article GET IT
Sensitivity analysis of dose-response model parameters for the bladder in prostate cancer radiotherapy. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 2025 Academic Article GET IT
Dose-response mapping of bladder and rectum in prostate cancer patients undergoing radiotherapy with and without baseline toxicity correction. Physics and imaging in radiation oncology. 2025 Academic Article GET IT
Integrating genetic polymorphisms and clinical data to develop predictive models for skin toxicity in breast cancer radiation therapy. Breast (Edinburgh, Scotland). 2025 Academic Article GET IT
A Polygenic Risk Score for Late Bladder Toxicity Following Radiotherapy for Non-Metastatic Prostate Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2025 Academic Article GET IT
Times cited: 2
Association of radiation-induced normal tissue toxicity with a high genetic risk for rheumatoid arthritis. Journal of the National Cancer Institute. 2025 Academic Article GET IT
Times cited: 1
Differential Effects of Endocrine Therapy Type on Quality of Life in Older (≥70 Years) Women with Early-Stage Breast Cancer. Annals of surgical oncology. 2025 Academic Article GET IT
Times cited: 1
Age-stratified analysis of health-related quality of life in patients with early-stage breast cancer receiving adjuvant radiation therapy and endocrine therapy. Journal of geriatric oncology. 2025 Academic Article GET IT
Times cited: 1
New rectum dose surface mapping methodology to identify rectal subregions associated with toxicities following prostate cancer radiotherapy. Physics and imaging in radiation oncology. 2025 Academic Article GET IT
Professional-patient discrepancies in assessing lung cancer radiotherapy symptoms: An international multicentre study. Lung cancer (Amsterdam, Netherlands). 2024 Academic Article GET IT
The Need to Enrich Population Diversity in Radiogenomic Research. International journal of radiation oncology, biology, physics. 2024 Editorial Article GET IT
Times cited: 1
Optimising inter-patient image registration for image-based data mining in breast radiotherapy. Physics and imaging in radiation oncology. 2024 Academic Article GET IT
Times cited: 1
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants. Nature genetics. 2023 Academic Article GET IT
Times cited: 71
Large-scale meta-genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types. JNCI cancer spectrum. 2023 Review GET IT
Times cited: 9
Contouring variation affects estimates of normal tissue complication probability for breast fibrosis after radiotherapy. Breast (Edinburgh, Scotland). 2023 Academic Article GET IT
Times cited: 4
Genome-wide association study of treatment-related toxicity two years following radiotherapy for breast cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2023 Academic Article GET IT
Times cited: 7
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry. American journal of human genetics. 2023 Academic Article GET IT
Times cited: 11
Predicting the germline dependence of hematuria risk in prostate cancer radiotherapy patients. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2023 Academic Article GET IT
Times cited: 6
Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry. 2023 GET IT
Times cited: 6
Comparing symptom reporting by prostate cancer patients and healthcare professionals in the international multicentre REQUITE study. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2022 Academic Article GET IT
Times cited: 3
The correlation between pre-treatment symptoms, acute and late toxicity and patient-reported health-related quality of life in non-small cell lung cancer patients: Results of the REQUITE study. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2022 Academic Article GET IT
Times cited: 10
Treatment time and circadian genotype interact to influence radiotherapy side-effects. A prospective European validation study using the REQUITE cohort. EBioMedicine. 2022 Academic Article GET IT
Times cited: 13
No Association Between Polygenic Risk Scores for Cancer and Development of Radiation Therapy Toxicity. International journal of radiation oncology, biology, physics. 2022 Academic Article GET IT
Times cited: 3
Ocular complications with the use of radium-223: a case series. Radiation oncology (London, England). 2022 Academic Article GET IT
Times cited: 2
Overview of health-related quality of life and toxicity of non-small cell lung cancer patients receiving curative-intent radiotherapy in a real-life setting (the REQUITE study). Lung cancer (Amsterdam, Netherlands). 2022 Academic Article GET IT
Times cited: 10
Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score. Prostate cancer and prostatic diseases. 2022 Academic Article GET IT
Times cited: 22
Factors associated with late local failure and its influence on survival in men undergoing prostate brachytherapy. Brachytherapy. 2022 Academic Article GET IT
Times cited: 7
Use of angiotensin converting enzyme inhibitors is associated with reduced risk of late bladder toxicity following radiotherapy for prostate cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2022 Academic Article GET IT
Times cited: 16
Development and Optimization of a Machine-Learning Prediction Model for Acute Desquamation After Breast Radiation Therapy in the Multicenter REQUITE Cohort. Advances in radiation oncology. 2022 Academic Article GET IT
Times cited: 11
A data science approach for early-stage prediction of Patient's susceptibility to acute side effects of advanced radiotherapy. Computers in biology and medicine. 2021 Academic Article GET IT
Times cited: 6
Development of a method for generating SNP interaction-aware polygenic risk scores for radiotherapy toxicity. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2021 Academic Article GET IT
Times cited: 17
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. 2021 GET IT
Times cited: 10
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. Nature communications. 2021 Academic Article GET IT
Times cited: 44
ATM Variants in Breast Cancer: Implications for Breast Radiation Therapy Treatment Recommendations. International journal of radiation oncology, biology, physics. 2021 Review GET IT
Times cited: 15
Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer. Prostate cancer and prostatic diseases. 2021 Academic Article GET IT
Times cited: 15
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nature genetics. 2021 Review GET IT
Times cited: 318
The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor. Cancers. 2020 Academic Article GET IT
Times cited: 21
External Validation of a Predictive Model for Acute Skin Radiation Toxicity in the REQUITE Breast Cohort. Frontiers in oncology. 2020 Academic Article GET IT
Times cited: 17
A Deep Learning Approach Validates Genetic Risk Factors for Late Toxicity After Prostate Cancer Radiotherapy in a REQUITE Multi-National Cohort. Frontiers in oncology. 2020 Academic Article GET IT
Times cited: 27
I-125 or Pd-103 for brachytherapy boost in men with high-risk prostate cancer: A comparison of survival and morbidity outcomes. Brachytherapy. 2020 Academic Article GET IT
Times cited: 3
Genomics models in radiotherapy: From mechanistic to machine learning. Medical physics. 2020 Review GET IT
Times cited: 18
Survey of Radiation Oncologists to Assess Interest and Potential Use of a Genetic Test Predicting Susceptibility for the Development of Toxicities After Prostate Cancer Radiation Therapy. Advances in radiation oncology. 2020 Academic Article GET IT
Times cited: 2
Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy. Journal of the National Cancer Institute. 2020 Academic Article GET IT
Times cited: 88
Use of genomics to balance cure and complications. Nature reviews. Clinical oncology. 2020 Comment GET IT
Response to Letter to the Editor: Regarding "Teaching Radiation and Cancer Biology to Radiation Oncology Residents: A 40-Year Perspective". Practical radiation oncology. 2019 Letter GET IT
Times cited: 1
Publisher Correction: Shared heritability and functional enrichment across six solid cancers. 2019 GET IT
Times cited: 3
Teaching Radiation and Cancer Biology to Radiation Oncology Residents: A 40-Year Perspective. Practical radiation oncology. 2019 Editorial Article GET IT
Times cited: 3
The Implications of Genetic Testing on Radiation Therapy Decisions: A Guide for Radiation Oncologists. International journal of radiation oncology, biology, physics. 2019 Review GET IT
Times cited: 74
REQUITE: A prospective multicentre cohort study of patients undergoing radiotherapy for breast, lung or prostate cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2019 Academic Article GET IT
Times cited: 72
Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 2019 GET IT
Times cited: 10
Shared heritability and functional enrichment across six solid cancers. Nature communications. 2019 Academic Article GET IT
Times cited: 84
Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2018 Academic Article GET IT
Times cited: 30
Radiogenomic Predictors of Adverse Effects following Charged Particle Therapy. International journal of particle therapy. 2018 Academic Article GET IT
Times cited: 6
Genomics, bio specimens, and other biological data: Current status and future directions. Medical physics. 2018 Review GET IT
Times cited: 3
Machine Learning and Radiogenomics: Lessons Learned and Future Directions. Frontiers in oncology. 2018 Review GET IT
Times cited: 61
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nature genetics. 2018 Academic Article GET IT
Times cited: 640
Radiogenomics: Identification of Genomic Predictors for Radiation Toxicity. Seminars in radiation oncology. 2017 Review GET IT
Times cited: 43
Radiogenomics and radiotherapy response modeling. Physics in medicine and biology. 2017 Review GET IT
Times cited: 46
Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era. Frontiers in oncology. 2017 Review GET IT
Times cited: 38
Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer. EBioMedicine. 2016 Review GET IT
Times cited: 76
Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2016 Review GET IT
Times cited: 105
Overview of the American Society for Radiation Oncology-National Institutes of Health-American Association of Physicists in Medicine Workshop 2015: Exploring Opportunities for Radiation Oncology in the Era of Big Data. International journal of radiation oncology, biology, physics. 2016 Editorial Article GET IT
Times cited: 27
Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity. British journal of cancer. 2016 Academic Article GET IT
Times cited: 20
Radiogenomics: A systems biology approach to understanding genetic risk factors for radiotherapy toxicity?. Cancer letters. 2016 Review GET IT
Times cited: 68
Prospective Randomized Trial of Prone Accelerated Intensity Modulated Breast Radiation Therapy With a Daily Versus Weekly Boost to the Tumor Bed. International journal of radiation oncology, biology, physics. 2015 Academic Article GET IT
Times cited: 13
How Will Big Data Improve Clinical and Basic Research in Radiation Therapy?. International journal of radiation oncology, biology, physics. 2015 Editorial Article GET IT
Times cited: 27
Lhermitte's Sign following VMAT-Based Head and Neck Radiation-Insights into Mechanism. PloS one. 2015 Academic Article GET IT
Times cited: 6
The Prediction of Radiotherapy Toxicity Using Single Nucleotide Polymorphism-Based Models: A Step Toward Prevention. Seminars in radiation oncology. 2015 Review GET IT
Times cited: 51
XRCC1 Polymorphism Associated With Late Toxicity After Radiation Therapy in Breast Cancer Patients. International journal of radiation oncology, biology, physics. 2015 Academic Article GET IT
Times cited: 64
Radiogenomics: radiobiology enters the era of big data and team science. International journal of radiation oncology, biology, physics. 2014 Editorial Article GET IT
Times cited: 94
Identification of SNPs associated with susceptibility for development of adverse reactions to radiotherapy. Pharmacogenomics. 2011 Academic Article GET IT
Times cited: 31
American Society for Radiation Oncology (ASTRO) survey of radiation biology educators in U.S. and Canadian radiation oncology residency programs. International journal of radiation oncology, biology, physics. 2009 Academic Article GET IT
Times cited: 18

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Background

education and training

Ph.D., University of Rochester 78
B.A., University of Rochester 73
M.S., University of Rochester 1976

Contact

full name

Barry Rosenstein

VIVO Weill Cornell Medical College

Barry Rosenstein Adjunct Professor of Radiation Biology in Radiation Oncology (Pending Appointment at Rank)

Publications

selected publications

Background

education and training

Contact

full name