selected publications
- Cell-Autonomous AR Dependence in Luminal Prostatic Epithelium Governs Survival and Lineage Plasticity. 2026 GET IT
- BPTF regulates androgen receptor activity by enhancing chromatin accessibility and stabilizing the AR-FOXA1 interaction. Nature communications. 2025 Academic Article GET IT
- Repertoire and clinical hierarchy of AR locus alterations in castration-resistant prostate cancer. Annals of oncology : official journal of the European Society for Medical Oncology. 2025 Academic Article GET IT
- Germline-somatic liaison dictates cancer subtype via de novo steroid biosynthesis. Cancer discovery. 2025 Academic Article GET IT
- A Randomized Controlled Phase 2 Trial Comparing Salvage Radiotherapy for Prostate Cancer Delivered in 4 Versus 2 Weeks (SHORTER): Acute Genitourinary and Gastrointestinal Patient-reported Outcomes at a Single Institution. European urology oncology. 2025 Academic Article GET IT
- Chemotherapy and the somatic mutation burden of sperm. JCI insight. 2025 Academic Article GET IT
- Direct measurement of the male germline mutation rate in individuals using sequential sperm samples. Nature communications. 2025 Academic Article GET IT
- Ascertaining provider-level implicit bias in electronic health records with rules-based natural language processing: A pilot study in the case of prostate cancer. PloS one. 2024 Academic Article GET IT
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Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate.
Nature communications.
2024
Academic Article
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Times cited: 8 -
Clonal Lineage Tracing with Somatic Delivery of Recordable Barcodes Reveals Migration Histories of Metastatic Prostate Cancer.
Cancer discovery.
2024
Academic Article
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Times cited: 7 -
Trends in Active Surveillance for Men With Intermediate-Risk Prostate Cancer.
JAMA network open.
2024
Academic Article
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Times cited: 15 - USP11 promotes prostate cancer progression by up-regulating AR and c-Myc activity. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT
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Transcriptomic Profiling of Primary Prostate Cancers and Nonlocalized Disease on Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography: A Multicenter Retrospective Study.
JCO precision oncology.
2024
Academic Article
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Times cited: 3 - Genomic Determinants Associated with Modes of Progression and Patterns of Failure in Metachronous Oligometastatic Castration-sensitive Prostate Cancer. European urology oncology. 2024 Academic Article GET IT
- Canonical AREs are tumor suppressive regulatory elements in the prostate. 2024 GET IT
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Distinct mesenchymal cell states mediate prostate cancer progression.
Nature communications.
2024
Academic Article
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Times cited: 25 -
Plasma metabolomics profiling of 580 patients from an Early Detection Research Network prostate cancer cohort.
Scientific data.
2023
Academic Article
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Times cited: 12 -
SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor-Induced Growth Suppression.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2023
Academic Article
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Times cited: 22 -
Differential Use of Radiotherapy Fractionation Regimens in Prostate Cancer.
JAMA network open.
2023
Academic Article
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Times cited: 11 -
Randomized phase II trial of MRI-guided salvage radiotherapy for prostate cancer in 4 weeks versus 2 weeks (SHORTER).
BMC cancer.
2023
Academic Article
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Times cited: 7 - Prostate cancer genetic alterations in Hispanic men. The Prostate. 2023 Academic Article GET IT
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Impact of Magnetic Resonance Imaging Targeting on Pathologic Upgrading and Downgrading at Prostatectomy: A Systematic Review and Meta-analysis.
European urology oncology.
2023
Review
GET IT
Times cited: 23 - Distinct mesenchymal cell states mediate prostate cancer progression. 2023 GET IT
- SMAD3 promotes expression and activity of the androgen receptor in prostate cancer. Nucleic acids research. 2023 Academic Article GET IT
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JAK inhibition shows two faces in prostate cancer.
Nature cancer.
2022
Comment
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Times cited: 3 -
Race and prostate cancer: genomic landscape.
Nature reviews. Urology.
2022
Review
GET IT
Times cited: 23 - Impact of Left-digit Age Bias in the Treatment of Localized Prostate Cancer. The Journal of urology. 2022 Academic Article GET IT
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Identifying synergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing.
Nature biotechnology.
2022
Academic Article
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Times cited: 85 -
Harm-to-Benefit of Three Decades of Prostate Cancer Screening in Black Men.
NEJM evidence.
2022
Academic Article
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Times cited: 125 -
A multidisciplinary approach to optimize primary prostate cancer biobanking.
Urologic oncology.
2022
Academic Article
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Times cited: 4 -
Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci.
JCI insight.
2022
Academic Article
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Times cited: 9 -
Trends in Androgen Deprivation Use in Men With Intermediate-Risk Prostate Cancer Who Underwent Radiation Therapy.
Advances in radiation oncology.
2022
Academic Article
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Times cited: 12 - Elevated expression of the colony-stimulating factor 1 (CSF1) induces prostatic intraepithelial neoplasia dependent of epithelial-Gp130. Oncogene. 2022 Academic Article GET IT
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G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer.
Nature communications.
2021
Academic Article
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Times cited: 31 -
Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity.
Cell reports.
2021
Academic Article
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Times cited: 30 - Re: Early Results of Unilateral Prostatic Artery Embolization as a Focal Therapy in Patients with Prostate Cancer under Active Surveillance: Cancer Prostate Embolization, a Pilot Study. Journal of vascular and interventional radiology : JVIR. 2021 Letter GET IT
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Tissue-Based Biomarkers for the Risk Stratification of Men With Clinically Localized Prostate Cancer.
Frontiers in oncology.
2021
Review
GET IT
Times cited: 29 - Tumor subtype defines distinct pathways of molecular and clinical progression in primary prostate cancer. The Journal of clinical investigation. 2021 Academic Article GET IT
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Three-dimensional prostate CT segmentation through fine-tuning of a pre-trained neural network using no reference labeling.
Proceedings of SPIE--the International Society for Optical Engineering.
2021
Academic Article
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Times cited: 2 -
Tumor size and genomic risk in localized prostate cancer.
Urologic oncology.
2021
Academic Article
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Times cited: 5 - Understanding the True Prevalence of Prostate Cancer Genomic Subtypes: Use of Inverse Probability Weighting to Correct for Biases in Molecularly Profiled Cohorts. The Journal of urology. 2021 Editorial Article GET IT
- Diversity in Androgen Receptor Action Among Treatment-naïve Prostate Cancers Is Reflected in Treatment Response Predictions and Molecular Subtypes. European urology open science. 2020 Academic Article GET IT
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Trends in Diagnosis and Disparities in Initial Management of High-Risk Prostate Cancer in the US.
JAMA network open.
2020
Academic Article
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Times cited: 20 -
Active Surveillance for Men with Intermediate Risk Prostate Cancer.
The Journal of urology.
2020
Academic Article
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Times cited: 2 -
Patient injuries and malfunctions associated with robotic prostatectomy: review of the manufacturer and user facility device experience database.
Journal of robotic surgery.
2020
Academic Article
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Times cited: 1 -
CDK12 Gene Alterations in Prostate Cancer: Present, but Clinically Actionable?.
European urology.
2020
Editorial Article
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Times cited: 1 -
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes.
Nature communications.
2020
Academic Article
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Times cited: 57 -
Prognostic value of the SPOP mutant genomic subclass in prostate cancer.
Urologic oncology.
2020
Academic Article
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Times cited: 6 -
Trends in the Use of Stereotactic Body Radiotherapy for Treatment of Prostate Cancer in the United States.
JAMA network open.
2020
Academic Article
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Times cited: 65 -
Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma.
Translational oncology.
2019
Academic Article
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Times cited: 30 -
The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation.
Nature immunology.
2019
Academic Article
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Times cited: 56 -
N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
The Journal of clinical investigation.
2019
Academic Article
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Times cited: 141 -
FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes.
Nature.
2019
Academic Article
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Times cited: 221 -
The Clinical Utility of the Genomic Prostate Score in Men with Very Low to Intermediate Risk Prostate Cancer.
The Journal of urology.
2019
Academic Article
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Times cited: 2 -
Intraductal carcinoma of the prostate in the absence of high-grade invasive carcinoma represents a molecularly distinct type of in situ carcinoma enriched with oncogenic driver mutations.
The Journal of pathology.
2019
Academic Article
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Times cited: 15 -
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
2019
GET IT
Times cited: 10 -
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Cancer cell.
2019
Academic Article
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Times cited: 83 -
Unraveling Prostate Cancer Genomics, Pathology, and Magnetic Resonance Imaging Visibility.
European urology.
2019
Editorial Article
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Times cited: 2 -
Impact of Pelvic Radiation Therapy on Inflatable Penile Prosthesis Reoperation Rates.
The journal of sexual medicine.
2018
Academic Article
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Times cited: 1 -
Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate.
Molecular cancer research : MCR.
2018
Academic Article
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Times cited: 53 -
SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 122 - Introduction to "Molecular drivers of prostate cancer development, progression, and resistance to therapy". Urologic oncology. 2018 Information Resource GET IT
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Impact of the SPOP Mutant Subtype on the Interpretation of Clinical Parameters in Prostate Cancer.
JCO precision oncology.
2018
Academic Article
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Times cited: 36 -
Molecular Subtypes of Prostate Cancer.
Current oncology reports.
2018
Information Resource
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Times cited: 31 -
The long tail of oncogenic drivers in prostate cancer.
Nature genetics.
2018
Academic Article
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Times cited: 682 -
SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 30 -
The Role of Gut Microbiome in the Pathogenesis of Prostate Cancer: A Prospective, Pilot Study.
Urology.
2017
Academic Article
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Times cited: 185 -
Vasectomy and Risk of Prostate Cancer in a Screening Trial.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2017
Academic Article
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Times cited: 11 -
Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics.
Journal of translational medicine.
2017
Academic Article
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Times cited: 7 -
Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.
Nature medicine.
2017
Academic Article
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Times cited: 293 -
Molecular alterations in prostate cancer and association with MRI features.
Prostate cancer and prostatic diseases.
2017
Academic Article
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Times cited: 13 -
Co-clinical Analysis of a Genetically Engineered Mouse Model and Human Prostate Cancer Reveals Significance of NKX3.1 Expression for Response to 5α-reductase Inhibition.
European urology.
2017
Academic Article
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Times cited: 17 -
SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.
Cancer cell.
2017
Academic Article
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Times cited: 172 -
Racial Variation in the Utility of Urinary Biomarkers PCA3 and T2ERG in a Large Multicenter Study.
The Journal of urology.
2017
Academic Article
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Times cited: 19 -
Prognostic Significance of a Negative Prostate Biopsy: An Analysis of Subjects Enrolled in a Prostate Cancer Screening Trial.
The Journal of urology.
2016
Academic Article
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Times cited: 14 -
DNA Repair in Prostate Cancer: Biology and Clinical Implications.
European urology.
2016
Information Resource
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Times cited: 120 -
The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics.
European urology.
2016
Information Resource
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Times cited: 58 -
Prostate size, nocturia and the digital rectal examination: a cohort study of 30 500 men.
BJU international.
2016
Academic Article
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Times cited: 19 - Editorial Comment. The Journal of urology. 2016 Article GET IT
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Clinical variability and molecular heterogeneity in prostate cancer.
Asian journal of andrology.
2016
Information Resource
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Times cited: 113 -
Lethal Prostate Cancer in the PLCO Cancer Screening Trial.
European urology.
2016
Academic Article
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Times cited: 9 -
Molecular subtyping of prostate cancer.
Current opinion in urology.
2016
Information Resource
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Times cited: 45 -
Decline in Prostate Cancer Screening by Primary Care Physicians: An Analysis of Trends in the Use of Digital Rectal Examination and Prostate Specific Antigen Testing.
The Journal of urology.
2016
Academic Article
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Times cited: 35 -
Shifting Paradigms for High-grade Prostatic Intraepithelial Neoplasia.
European urology.
2015
Editorial Article
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Times cited: 4 -
The Molecular Taxonomy of Primary Prostate Cancer.
Cell.
2015
Academic Article
GET IT
Times cited: 2538 -
Efficacy of Prostate-Specific Antigen Screening: Use of Regression Discontinuity in the PLCO Cancer Screening Trial.
JAMA oncology.
2015
Letter
GET IT
Times cited: 10 -
SPOP mutation leads to genomic instability in prostate cancer.
eLife.
2015
Academic Article
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Times cited: 160 -
Reprint of: The prostate cancer genome: Perspectives and potential.
Urologic oncology.
2015
Information Resource
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Times cited: 7 -
Genomic rearrangements in prostate cancer.
Current opinion in urology.
2015
Information Resource
GET IT
Times cited: 27 - National Trends and Cost of Minimally Invasive Surgery in Urology. Urology Practice. 2015 Article GET IT
- National trends and cost of minimally invasive surgery in urology. Urology Practice. 2015 Article GET IT
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National Trends and Cost of Minimally Invasive Surgery in Urology.
Urology practice.
2014
Academic Article
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Times cited: 11 -
Unraveling the clonal hierarchy of somatic genomic aberrations.
Genome biology.
2014
Academic Article
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Times cited: 85 -
Evidence for molecular differences in prostate cancer between African American and Caucasian men.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2014
Academic Article
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Times cited: 140 -
Incidental prostate cancer in transurethral resection of the prostate specimens in the modern era.
Advances in urology.
2014
Academic Article
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Times cited: 33 -
Recurrent prostate cancer genomic alterations predict response to brachytherapy treatment.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2014
Academic Article
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Times cited: 25 -
SPOP mutations in prostate cancer across demographically diverse patient cohorts.
Neoplasia (New York, N.Y.).
2014
Academic Article
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Times cited: 133 -
TMPRSS2:ERG gene fusion predicts subsequent detection of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2013
Academic Article
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Times cited: 93 -
The prostate cancer genome: perspectives and potential.
Urologic oncology.
2013
Information Resource
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Times cited: 41 -
Re: Stoehr et al. Lack of evidence for frequent MED12 p.L1224F mutation in prostate tumours from Caucasian patients. J Pathol 2013; 230: 453-456.
The Journal of pathology.
2013
Article
GET IT
Times cited: 1 -
Evolution of novel biomarkers for detection of prostate cancer.
The Journal of urology.
2013
Editorial Article
GET IT
Times cited: 8 -
Molecular characterization of prostate cancer following androgen deprivation: the devil in the details.
European urology.
2013
Editorial Article
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Times cited: 3 -
The mutational landscape of prostate cancer.
European urology.
2013
Information Resource
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Times cited: 187 -
Punctuated evolution of prostate cancer genomes.
Cell.
2013
Academic Article
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Times cited: 1092 -
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
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Times cited: 220 -
Deletion or underexpression of the Y-chromosome genes CDY2 and HSFY is associated with maturation arrest in American men with nonobstructive azoospermia.
Asian journal of andrology.
2012
Academic Article
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Times cited: 32 -
Next-generation prostate cancer biobanking: toward a processing protocol amenable for the International Cancer Genome Consortium.
Diagnostic molecular pathology : the American journal of surgical pathology, part B.
2012
Academic Article
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Times cited: 25 -
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
Nature genetics.
2012
Academic Article
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Times cited: 1326 -
Molecular genetics of prostate cancer: emerging appreciation of genetic complexity.
Histopathology.
2012
Information Resource
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Times cited: 48 -
Ureteroileal anastomosis with intraluminal visualization: technique and outcomes.
Urology.
2010
Academic Article
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Times cited: 4 -
DeltaNp63 antagonizes p53 to regulate mesoderm induction in Xenopus laevis.
Developmental biology.
2009
Academic Article
GET IT
Times cited: 13 -
Association of procedure volume with radical cystectomy outcomes in a nationwide database.
The Journal of urology.
2007
Academic Article
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Times cited: 100 -
Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis.
Cancer research.
2006
Academic Article
GET IT
Times cited: 196 -
The DNA binding activity of p53 displays reaction-diffusion kinetics.
Biophysical journal.
2006
Academic Article
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Times cited: 65 -
p63 and epithelial biology.
Experimental cell research.
2006
Information Resource
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Times cited: 104 -
Ultraviolet radiation induces phosphorylation and ubiquitin-mediated degradation of DeltaNp63alpha.
Cell cycle (Georgetown, Tex.).
2005
Academic Article
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Times cited: 60 -
p53 family members: similar biochemistry, different biology.
Cancer biology & therapy.
2005
Article
GET IT
Times cited: 4 -
IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium.
Cancer research.
2005
Academic Article
GET IT
Times cited: 72 -
Delta Np63 alpha expression is regulated by the phosphoinositide 3-kinase pathway.
The Journal of biological chemistry.
2003
Academic Article
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Times cited: 65 -
Inhibition of epidermal growth factor receptor signaling decreases p63 expression in head and neck squamous carcinoma cells.
The Laryngoscope.
2003
Academic Article
GET IT
Times cited: 47