Rice, Charles M.

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Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells. Journal of virology. 2019 Academic Article GET IT
Times cited: 13
Characterization of Novel Splice Variants of Zinc Finger Antiviral Protein (ZAP). Journal of virology. 2019 Academic Article GET IT
Times cited: 67
ZAP's stress granule localization is correlated with its antiviral activity and induced by virus replication. PLoS pathogens. 2019 Academic Article GET IT
Times cited: 38
Identification and transcriptome analysis of erythroblastic island macrophages. Blood. 2019 Academic Article GET IT
Times cited: 103
Taming a beast: lessons from the domestication of hepatitis C virus. Current opinion in virology. 2019 Information Resource GET IT
Times cited: 9
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape. Nature immunology. 2019 Academic Article GET IT
Times cited: 43
IFITM3 directly engages and shuttles incoming virus particles to lysosomes. Nature chemical biology. 2019 Academic Article GET IT
Times cited: 149
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids. Cell. 2018 Academic Article GET IT
Times cited: 173
Identification of a Small Interface between the Methyltransferase and RNA Polymerase of NS5 that is Essential for Zika Virus Replication. Scientific reports. 2018 Academic Article GET IT
Times cited: 14
T time for ADAR: ADAR1 is required for T cell self-tolerance. EMBO reports. 2018 Article GET IT
Times cited: 8
A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell reports. 2018 Academic Article GET IT
Times cited: 53
Friend and foe, HNRNPC takes on immunostimulatory RNAs in breast cancer cells. The EMBO journal. 2018 Article GET IT
Times cited: 13
NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus. Cell reports. 2018 Academic Article GET IT
Times cited: 18
Antiviral resistance of stem cells. Current opinion in immunology. 2018 Information Resource GET IT
Times cited: 20
Longitudinal transcriptomic characterization of the immune response to acute hepatitis C virus infection in patients with spontaneous viral clearance. PLoS pathogens. 2018 Academic Article GET IT
Times cited: 33
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20. Journal of virology. 2018 Academic Article GET IT
Times cited: 40
Male germ cells support long-term propagation of Zika virus. Nature communications. 2018 Academic Article GET IT
Times cited: 62
Viral persistence, liver disease, and host response in a hepatitis C-like virus rat model. Hepatology (Baltimore, Md.). 2018 Academic Article GET IT
Times cited: 54
Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies. Virus research. 2018 Information Resource GET IT
Times cited: 81
New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product. Emerging infectious diseases. 2018 Academic Article GET IT
Times cited: 79
Genetic Variation at IFNL4 Influences Extrahepatic Interferon-Stimulated Gene Expression in Chronic HCV Patients. The Journal of infectious diseases. 2018 Academic Article GET IT
Times cited: 16
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown. Cell. 2018 Academic Article GET IT
Times cited: 342
A research agenda for curing chronic hepatitis B virus infection. Hepatology (Baltimore, Md.). 2018 Academic Article GET IT
Times cited: 70
Pan-Genotype Hepatitis E Virus Replication in Stem Cell-Derived Hepatocellular Systems. Gastroenterology. 2017 Academic Article GET IT
Times cited: 44
Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2017 Academic Article GET IT
Times cited: 248
Research priorities for the discovery of a cure for chronic hepatitis B: Report of a workshop. Antiviral research. 2017 Conference Paper GET IT
Times cited: 23
A robust cell culture system supporting the complete life cycle of hepatitis B virus. Scientific reports. 2017 Academic Article GET IT
Times cited: 60
miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS pathogens. 2017 Academic Article GET IT
Times cited: 24
Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread. Cell host & microbe. 2017 Academic Article GET IT
Times cited: 44
Differential Regulation of Lipoprotein and Hepatitis C Virus Secretion by Rab1b. Cell reports. 2017 Academic Article GET IT
Times cited: 28
Development of a recombinant yellow fever vector expressing a HIV clade C founder envelope gp120. Journal of virological methods. 2017 Academic Article GET IT
Times cited: 2
Global mapping of miRNA-target interactions in cattle (Bos taurus). Scientific reports. 2017 Academic Article GET IT
Times cited: 16
Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer. Molecular cell. 2017 Academic Article GET IT
Times cited: 68
Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- Mice. Cellular and molecular gastroenterology and hepatology. 2017 Academic Article GET IT
Times cited: 7
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease. Science translational medicine. 2017 Academic Article GET IT
Times cited: 129
Mouse models of acute and chronic hepacivirus infection. Science (New York, N.Y.). 2017 Academic Article GET IT
Times cited: 102
Loss of Sendai virus C protein leads to accumulation of RIG-I immunostimulatory defective interfering RNA. The Journal of general virology. 2017 Academic Article GET IT
Times cited: 23
Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell. 2017 Academic Article GET IT
Times cited: 245
Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment. Journal of virology. 2017 Academic Article GET IT
Times cited: 36
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons. Gastroenterology. 2017 Academic Article GET IT
Times cited: 23
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity. Immunity. 2017 Academic Article GET IT
Times cited: 83
Single-molecule imaging reveals the translocation and DNA looping dynamics of hepatitis C virus NS3 helicase. Protein science : a publication of the Protein Society. 2017 Academic Article GET IT
Times cited: 16
Green fluorescent protein-tagged apolipoprotein E: A useful marker for the study of hepatic lipoprotein egress. Traffic (Copenhagen, Denmark). 2017 Academic Article GET IT
Times cited: 6
TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP). PLoS pathogens. 2017 Academic Article GET IT
Times cited: 138
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. The Journal of experimental medicine. 2016 Academic Article GET IT
Times cited: 13
Present and not reporting for duty: dsRNAi in mammalian cells. The EMBO journal. 2016 Article GET IT
Times cited: 6
Expanding the Host Range of Hepatitis C Virus through Viral Adaptation. mBio. 2016 Academic Article GET IT
Times cited: 15
Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance. Journal of virology. 2016 Academic Article GET IT
Times cited: 17
Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir. PloS one. 2016 Academic Article GET IT
Times cited: 59
Hepatitis C Virus-From Discovery to Cure: The 2016 Lasker-DeBakey Clinical Medical Research Award. JAMA. 2016 Article GET IT
Times cited: 2
Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA. Journal of hepatology. 2016 Academic Article GET IT
Times cited: 66
Identification of Interferon-Stimulated Genes with Antiretroviral Activity. Cell host & microbe. 2016 Academic Article GET IT
Times cited: 173
Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus. Antimicrobial agents and chemotherapy. 2016 Academic Article GET IT
Times cited: 36
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action. The Journal of biological chemistry. 2016 Academic Article GET IT
Times cited: 13
Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells. Journal of hepatology. 2016 Academic Article GET IT
Times cited: 68
Reply. Gastroenterology. 2016 Article GET IT
Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies. Virology. 2016 Academic Article GET IT
Times cited: 14
Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid. Molecular therapy : the journal of the American Society of Gene Therapy. 2016 Academic Article GET IT
Times cited: 89
A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration. Cell host & microbe. 2016 Academic Article GET IT
Times cited: 106
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2016 Academic Article GET IT
Times cited: 58
Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication. Journal of virology. 2016 Academic Article GET IT
Times cited: 23
miRNA-target chimeras reveal miRNA 3'-end pairing as a major determinant of Argonaute target specificity. Nature communications. 2015 Academic Article GET IT
Times cited: 228
The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production. PLoS pathogens. 2015 Academic Article GET IT
Times cited: 17
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens. Nature protocols. 2015 Academic Article GET IT
Times cited: 116
Mopping up miRNA: An integrated HBV transcript disrupts liver homeostasis by sequestering miR-122. Journal of hepatology. 2015 Editorial Article GET IT
Times cited: 10
Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin. Gastroenterology. 2015 Academic Article GET IT
Times cited: 109
SEC14L2 enables pan-genotype HCV replication in cell culture. Nature. 2015 Academic Article GET IT
Times cited: 107
Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry. Cell reports. 2015 Academic Article GET IT
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation. Nature immunology. 2015 Academic Article GET IT
Times cited: 216
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus. Scientific reports. 2015 Academic Article GET IT
Times cited: 248
Hepatitis B virus induces RNR-R2 expression via DNA damage response activation. Journal of hepatology. 2015 Academic Article GET IT
Times cited: 19
ATP-dependent effector-like functions of RIG-I-like receptors. Molecular cell. 2015 Academic Article GET IT
Times cited: 55
Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice. Hepatology (Baltimore, Md.). 2015 Academic Article GET IT
Times cited: 21
Fast hepatitis C virus RNA elimination and NS5A redistribution by NS5A inhibitors studied by a multiplex assay approach. Antimicrobial agents and chemotherapy. 2015 Academic Article GET IT
Times cited: 19
Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors. PloS one. 2015 Academic Article GET IT
Times cited: 38
Hepatitis C virus RNA functionally sequesters miR-122. Cell. 2015 Academic Article GET IT
Times cited: 278
To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes. Trends in cell biology. 2015 Information Resource GET IT
Times cited: 60
Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4. mBio. 2015 Academic Article GET IT
Times cited: 16
Interferons and viruses: an evolutionary arms race of molecular interactions. Trends in immunology. 2015 Information Resource GET IT
Times cited: 316
A serpin shapes the extracellular environment to prevent influenza A virus maturation. Cell. 2015 Academic Article GET IT
Times cited: 119
Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus. Hepatology (Baltimore, Md.). 2015 Academic Article GET IT
Times cited: 30
The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus. Immunity. 2014 Academic Article GET IT
Times cited: 251
New Methods in Tissue Engineering: Improved Models for Viral Infection. Annual review of virology. 2014 Academic Article GET IT
Times cited: 20
Insufficient interleukin-12 signalling favours differentiation of human CD4(+) and CD8(+) T cells into GATA-3(+) and GATA-3(+) T-bet(+) subsets in humanized mice. Immunology. 2014 Academic Article GET IT
Times cited: 22
Broadly neutralizing antibodies abrogate established hepatitis C virus infection. Science translational medicine. 2014 Academic Article GET IT
Times cited: 193
Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus. Journal of virology. 2014 Academic Article GET IT
Times cited: 65
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 212
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents. Hepatology (Baltimore, Md.). 2014 Academic Article GET IT
Times cited: 50
Seed sequence-matched controls reveal limitations of small interfering RNA knockdown in functional and structural studies of hepatitis C virus NS5A-MOBKL1B interaction. Journal of virology. 2014 Academic Article GET IT
Times cited: 19
Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut. 2014 Academic Article GET IT
Times cited: 104
Hepatitis C virus genotype 5a subgenomic replicons for evaluation of direct-acting antiviral agents. Antimicrobial agents and chemotherapy. 2014 Academic Article GET IT
Times cited: 31
Hepatitis C: Treatment triumphs. Nature. 2014 Article GET IT
Times cited: 28
Multifaceted activities of type I interferon are revealed by a receptor antagonist. Science signaling. 2014 Academic Article GET IT
Times cited: 88
Identification of AP80978, a novel small-molecule inhibitor of hepatitis C virus replication that targets NS4B. Antimicrobial agents and chemotherapy. 2014 Academic Article GET IT
Times cited: 20
Interferon lambda alleles predict innate antiviral immune responses and hepatitis C virus permissiveness. Cell host & microbe. 2014 Academic Article GET IT
Times cited: 82
Interferon-stimulated genes: a complex web of host defenses. Annual review of immunology. 2014 Information Resource GET IT
Times cited: 2174
Virus associated malignancies: the role of viral hepatitis in hepatocellular carcinoma. Seminars in cancer biology. 2014 Information Resource GET IT
Times cited: 137
Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource. Hepatology (Baltimore, Md.). 2014 Academic Article GET IT
Times cited: 1101
Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection. Nature medicine. 2013 Academic Article GET IT
Times cited: 220
Utility of humanized BLT mice for analysis of dengue virus infection and antiviral drug testing. Journal of virology. 2013 Academic Article GET IT
Times cited: 50
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature. 2013 Academic Article GET IT
Times cited: 718
Single cell analysis of HCV-infected patient hepatocytes: the science is no longer science fiction. Gastroenterology. 2013 Editorial Article GET IT
Times cited: 4
MX2 is an interferon-induced inhibitor of HIV-1 infection. Nature. 2013 Academic Article GET IT
Times cited: 395
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage. The EMBO journal. 2013 Academic Article GET IT
Times cited: 260
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 224
The ins and outs of hepatitis C virus entry and assembly. Nature reviews. Microbiology. 2013 Information Resource GET IT
Times cited: 305
Somatic hypermutations confer rheumatoid factor activity in hepatitis C virus-associated mixed cryoglobulinemia. Arthritis and rheumatism. 2013 Academic Article GET IT
Times cited: 40
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1). Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 149
Completion of the entire hepatitis C virus life cycle in genetically humanized mice. Nature. 2013 Academic Article GET IT
Times cited: 192
Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice. Journal of immunology (Baltimore, Md. : 1950). 2013 Academic Article GET IT
Times cited: 56
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies. Nature medicine. 2013 Information Resource GET IT
Times cited: 461
Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines. Virology. 2013 Academic Article GET IT
Times cited: 46
Different requirements for scavenger receptor class B type I in hepatitis C virus cell-free versus cell-to-cell transmission. Journal of virology. 2013 Academic Article GET IT
Times cited: 67
Ultrastructural analysis of hepatitis C virus particles. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 233
Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection. Nature medicine. 2013 Academic Article GET IT
Times cited: 124
Development of a multiplex phenotypic cell-based high throughput screening assay to identify novel hepatitis C virus antivirals. Antiviral research. 2013 Academic Article GET IT
Times cited: 14
Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype. Journal of virology. 2013 Academic Article GET IT
Times cited: 68
Identification of a pegivirus (GB virus-like virus) that infects horses. Journal of virology. 2013 Academic Article GET IT
Times cited: 79
Structures of hepatitis C virus nonstructural proteins required for replicase assembly and function. Current opinion in virology. 2013 Information Resource GET IT
Times cited: 45
Identification of rodent homologs of hepatitis C virus and pegiviruses. mBio. 2013 Academic Article GET IT
Times cited: 167
A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans. PloS one. 2013 Academic Article GET IT
Times cited: 153
Expression of heterologous proteins flanked by NS3-4A cleavage sites within the hepatitis C virus polyprotein. Virology. 2013 Academic Article GET IT
Times cited: 17
Genetic and functional characterization of the N-terminal region of the hepatitis C virus NS2 protein. Journal of virology. 2013 Academic Article GET IT
Times cited: 18
The frequency of CD127(+) hepatitis C virus (HCV)-specific T cells but not the expression of exhaustion markers predicts the outcome of acute HCV infection. Journal of virology. 2013 Academic Article GET IT
Times cited: 44
Inhibition of HIV-1 particle assembly by 2',3'-cyclic-nucleotide 3'-phosphodiesterase. Cell host & microbe. 2012 Academic Article GET IT
Times cited: 45
Flavivirus replication complex assembly revealed by DNAJC14 functional mapping. Journal of virology. 2012 Academic Article GET IT
Times cited: 43
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 153
Broadly neutralizing immune responses against hepatitis C virus induced by vectored measles viruses and a recombinant envelope protein booster. Journal of virology. 2012 Academic Article GET IT
Times cited: 36
Efficient replication of genotype 3a and 4a hepatitis C virus replicons in human hepatoma cells. Antimicrobial agents and chemotherapy. 2012 Academic Article GET IT
Times cited: 112
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology. 2012 Academic Article GET IT
Times cited: 140
Study of hepatitis C virus entry in genetically humanized mice. Methods (San Diego, Calif.). 2012 Academic Article GET IT
Times cited: 15
Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity. PloS one. 2012 Academic Article GET IT
Times cited: 61
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 290
Serology-enabled discovery of genetically diverse hepaciviruses in a new host. Journal of virology. 2012 Academic Article GET IT
Times cited: 205
Interferon α-stimulated natural killer cells from patients with acute hepatitis C virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX accessory molecule-1. The Journal of infectious diseases. 2012 Academic Article GET IT
Times cited: 38
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response. The Journal of experimental medicine. 2012 Academic Article GET IT
Times cited: 134
C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1. Journal of virology. 2012 Academic Article GET IT
Times cited: 37
Modeling hepatitis C virus infection using human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 196
A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo. Hepatology (Baltimore, Md.). 2011 Academic Article GET IT
Times cited: 111
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells. Hepatology (Baltimore, Md.). 2011 Academic Article GET IT
Times cited: 75
Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures. Hepatology (Baltimore, Md.). 2011 Academic Article GET IT
Times cited: 162
Interferon-stimulated genes and their antiviral effector functions. Current opinion in virology. 2011 Information Resource GET IT
Times cited: 954
Innate immunity: trolling, responding and protecting against viral infections. Current opinion in virology. 2011 Editorial Article GET IT
A genetically humanized mouse model for hepatitis C virus infection. Nature. 2011 Academic Article GET IT
Times cited: 310
Characterization of a canine homolog of hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 2011 Academic Article GET IT
Times cited: 227
Delayed induction, not impaired recruitment, of specific CD8⁺ T cells causes the late onset of acute hepatitis C. Gastroenterology. 2011 Academic Article GET IT
Times cited: 56
Hepatitis C virus co-opts Ras-GTPase-activating protein-binding protein 1 for its genome replication. Journal of virology. 2011 Academic Article GET IT
Times cited: 54
Locking out hepatitis C. Nature medicine. 2011 Article GET IT
Times cited: 6
A diverse range of gene products are effectors of the type I interferon antiviral response. Nature. 2011 Academic Article GET IT
Times cited: 1863
Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset. Blood. 2011 Academic Article GET IT
Times cited: 162
End game: getting the most out of microRNAs. Proceedings of the National Academy of Sciences of the United States of America. 2011 Article GET IT
Times cited: 1
Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2Rγ(null) humanized mice. Blood. 2011 Academic Article GET IT
Times cited: 235
A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease. Gastroenterology. 2011 Academic Article GET IT
Times cited: 255
Identification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulator. PLoS pathogens. 2011 Academic Article GET IT
Times cited: 61
Turning hepatitis C into a real virus. Annual review of microbiology. 2011 Information Resource GET IT
Times cited: 50
Suppression of inflammation by a synthetic histone mimic. Nature. 2010 Academic Article GET IT
Times cited: 1304
Cross-genotypic polyclonal anti-HCV antibodies from human ascitic fluid. Journal of virological methods. 2010 Academic Article GET IT
Times cited: 2
Evaluation of combination therapy against hepatitis C virus infection in human liver chimeric mice. Journal of hepatology. 2010 Editorial Article GET IT
Times cited: 4
Evaluation of yellow fever virus 17D strain as a new vector for HIV-1 vaccine development. Vaccine. 2010 Academic Article GET IT
Times cited: 19
A big role for small RNAs in influenza virus replication. Proceedings of the National Academy of Sciences of the United States of America. 2010 Article GET IT
Times cited: 9
Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry. Journal of virology. 2010 Academic Article GET IT
Times cited: 35
Immunogenicity and protective efficacy of a recombinant yellow fever vaccine against the murine malarial parasite Plasmodium yoelii. Vaccine. 2010 Academic Article GET IT
Times cited: 21
Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication. Journal of virology. 2010 Academic Article GET IT
Times cited: 95
Creation and characterization of a cell-death reporter cell line for hepatitis C virus infection. Antiviral research. 2010 Academic Article GET IT
Times cited: 8
Identification of a dominant negative inhibitor of human zinc finger antiviral protein reveals a functional endogenous pool and critical homotypic interactions. Journal of virology. 2010 Academic Article GET IT
Times cited: 28
New horizons for studying human hepatotropic infections. The Journal of clinical investigation. 2010 Article GET IT
Times cited: 44
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle. Proceedings of the National Academy of Sciences of the United States of America. 2010 Academic Article GET IT
Times cited: 67
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures. Proceedings of the National Academy of Sciences of the United States of America. 2010 Academic Article GET IT
Times cited: 182
Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system. Nature biotechnology. 2010 Academic Article GET IT
Times cited: 217
Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics. PLoS pathogens. 2010 Academic Article GET IT
Times cited: 347
Antisense gets a grip on miR-122 in chimpanzees. Science translational medicine. 2010 Article GET IT
Times cited: 14
Role of scavenger receptor class B type I in hepatitis C virus entry: kinetics and molecular determinants. Journal of virology. 2010 Academic Article GET IT
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism. Proceedings of the National Academy of Sciences of the United States of America. 2009 Academic Article GET IT
Times cited: 195
The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 264
Genetic analysis of the carboxy-terminal region of the hepatitis C virus core protein. Journal of virology. 2009 Academic Article GET IT
Times cited: 35
Towards a small animal model for hepatitis C. EMBO reports. 2009 Information Resource GET IT
Times cited: 66
Determinants of the hepatitis C virus nonstructural protein 2 protease domain required for production of infectious virus. Journal of virology. 2009 Academic Article GET IT
Times cited: 48
Genetic variation in CLDN1 and susceptibility to hepatitis C virus infection. Journal of viral hepatitis. 2009 Academic Article GET IT
Times cited: 20
Priming of protective T cell responses against virus-induced tumors in mice with human immune system components. The Journal of experimental medicine. 2009 Academic Article GET IT
Times cited: 248
Mutations in hepatitis C virus E2 located outside the CD81 binding sites lead to escape from broadly neutralizing antibodies but compromise virus infectivity. Journal of virology. 2009 Academic Article GET IT
Times cited: 83
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells. Nature. 2009 Academic Article GET IT
Times cited: 780
Genomic analysis reveals a potential role for cell cycle perturbation in HCV-mediated apoptosis of cultured hepatocytes. PLoS pathogens. 2009 Academic Article GET IT
Times cited: 110
Internal initiation stimulates production of p8 minicore, a member of a newly discovered family of hepatitis C virus core protein isoforms. Journal of virology. 2009 Academic Article GET IT
Times cited: 40
CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells. The Journal of general virology. 2009 Academic Article GET IT
Times cited: 160
Predicting response to hepatitis C therapy. The Journal of clinical investigation. 2009 Article GET IT
Times cited: 4
Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells. Hepatology (Baltimore, Md.). 2008 Academic Article GET IT
Times cited: 217
Stable cytotoxic T cell escape mutation in hepatitis C virus is linked to maintenance of viral fitness. PLoS pathogens. 2008 Academic Article GET IT
Times cited: 77
A dynamic view of hepatitis C virus replication complexes. Journal of virology. 2008 Academic Article GET IT
Times cited: 120
Transdominant inhibition of bovine viral diarrhea virus entry. Journal of virology. 2007 Academic Article GET IT
Times cited: 16
Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type I interferon in the hepatitis C virus-infected liver. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. 2007 Academic Article GET IT
Times cited: 22
Bovine viral diarrhea virus core is an intrinsically disordered protein that binds RNA. Journal of virology. 2007 Academic Article GET IT
Times cited: 36
Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein. Journal of virology. 2007 Academic Article GET IT
Times cited: 173
3' RNA elements in hepatitis C virus replication: kissing partners and long poly(U). Journal of virology. 2007 Academic Article GET IT
Times cited: 108
Clonal expansion of immunoglobulin M+CD27+ B cells in HCV-associated mixed cryoglobulinemia. Blood. 2007 Academic Article GET IT
Times cited: 142
Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients. The Journal of experimental medicine. 2007 Academic Article GET IT
Times cited: 104
Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies. Vaccine. 2007 Academic Article GET IT
Times cited: 76
Alanine scanning of the hepatitis C virus core protein reveals numerous residues essential for production of infectious virus. Journal of virology. 2007 Academic Article GET IT
Times cited: 100
Cellular cofactors affecting hepatitis C virus infection and replication. Proceedings of the National Academy of Sciences of the United States of America. 2007 Academic Article GET IT
Times cited: 486
The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication. Journal of virology. 2007 Academic Article GET IT
Times cited: 91
Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus. Journal of virology. 2007 Academic Article GET IT
Times cited: 376
High-avidity monoclonal antibodies against the human scavenger class B type I receptor efficiently block hepatitis C virus infection in the presence of high-density lipoprotein. Journal of virology. 2007 Academic Article GET IT
Times cited: 125
Replication of hepatitis C virus. Nature reviews. Microbiology. 2007 Information Resource GET IT
Times cited: 1055
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry. Nature. 2007 Academic Article GET IT
Times cited: 953
Evidence for a functional RNA element in the hepatitis C virus core gene. Proceedings of the National Academy of Sciences of the United States of America. 2007 Academic Article GET IT
Times cited: 110
Superinfection exclusion in cells infected with hepatitis C virus. Journal of virology. 2007 Academic Article GET IT
Times cited: 126
Flying under the radar: the immunobiology of hepatitis C. Annual review of immunology. 2007 Information Resource GET IT
Times cited: 262
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection. The Journal of clinical investigation. 2006 Academic Article GET IT
Times cited: 137
Mathematical modeling of subgenomic hepatitis C virus replication in Huh-7 cells. Journal of virology. 2006 Academic Article GET IT
Times cited: 90
Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation. Blood. 2006 Academic Article GET IT
Times cited: 47
Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics. Gastroenterology. 2006 Academic Article GET IT
Times cited: 489
Diverse CD81 proteins support hepatitis C virus infection. Journal of virology. 2006 Academic Article GET IT
Times cited: 137
Silencing of USP18 potentiates the antiviral activity of interferon against hepatitis C virus infection. Gastroenterology. 2006 Academic Article GET IT
Times cited: 133
Tracking and elucidating alphavirus-host protein interactions. The Journal of biological chemistry. 2006 Academic Article GET IT
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The NS5A protein of bovine viral diarrhea virus contains an essential zinc-binding site similar to that of the hepatitis C virus NS5A protein. Journal of virology. 2006 Academic Article GET IT
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Structure of the catalytic domain of the hepatitis C virus NS2-3 protease. Nature. 2006 Academic Article GET IT
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Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells. Hepatology (Baltimore, Md.). 2006 Academic Article GET IT
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Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro. Proceedings of the National Academy of Sciences of the United States of America. 2006 Academic Article GET IT
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Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C. Blood. 2006 Academic Article GET IT
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Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry. Journal of virology. 2006 Academic Article GET IT
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Liver-directed gamma interferon gene delivery in chronic hepatitis C. Journal of virology. 2005 Academic Article GET IT
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Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes. The Journal of experimental medicine. 2005 Academic Article GET IT
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Unravelling hepatitis C virus replication from genome to function. Nature. 2005 Information Resource GET IT
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Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C. The Journal of infectious diseases. 2005 Academic Article GET IT
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Complete replication of hepatitis C virus in cell culture. Science (New York, N.Y.). 2005 Academic Article GET IT
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Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature. 2005 Academic Article GET IT
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Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C. Blood. 2005 Academic Article GET IT
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Mathematical modeling of primary hepatitis C infection: noncytolytic clearance and early blockage of virion production. Gastroenterology. 2005 Academic Article GET IT
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Requirements at the 3' end of the sindbis virus genome for efficient synthesis of minus-strand RNA. Journal of virology. 2005 Academic Article GET IT
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Dual mechanisms of pestiviral superinfection exclusion at entry and RNA replication. Journal of virology. 2005 Academic Article GET IT
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Identification of microRNAs of the herpesvirus family. Nature methods. 2005 Academic Article GET IT
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Yellow fever 17D as a vaccine vector for microbial CTL epitopes: protection in a rodent malaria model. The Journal of experimental medicine. 2005 Academic Article GET IT
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Genetic interactions between hepatitis C virus replicons. Journal of virology. 2004 Academic Article GET IT
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Hepatitis C virus core protein associates with detergent-resistant membranes distinct from classical plasma membrane rafts. Journal of virology. 2004 Academic Article GET IT
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An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication. Journal of virology. 2004 Academic Article GET IT
Times cited: 140
Long-term persistence of infection in chimpanzees inoculated with an infectious hepatitis C virus clone is associated with a decrease in the viral amino acid substitution rate and low levels of heterogeneity. Journal of virology. 2004 Academic Article GET IT
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The NS5A protein of hepatitis C virus is a zinc metalloprotein. The Journal of biological chemistry. 2004 Academic Article GET IT
Times cited: 274
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication. Proceedings of the National Academy of Sciences of the United States of America. 2004 Academic Article GET IT
Times cited: 287
Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner. Journal of virology. 2004 Academic Article GET IT
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PKR-dependent and -independent mechanisms are involved in translational shutoff during Sindbis virus infection. Journal of virology. 2004 Academic Article GET IT
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Characterization of infectious retroviral pseudotype particles bearing hepatitis C virus glycoproteins. Journal of virology. 2004 Academic Article GET IT
Times cited: 82
Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes. Journal of virology. 2004 Academic Article GET IT
Times cited: 223
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity. Proceedings of the National Academy of Sciences of the United States of America. 2004 Academic Article GET IT
Times cited: 187
Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees. Hepatology (Baltimore, Md.). 2004 Academic Article GET IT
Times cited: 124
Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus. Journal of virology. 2004 Academic Article GET IT
Times cited: 61
Uncleaved NS2-3 is required for production of infectious bovine viral diarrhea virus. Journal of virology. 2004 Academic Article GET IT
Times cited: 75
A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication. Journal of virology. 2004 Academic Article GET IT
Times cited: 193
CD81 is required for hepatitis C virus glycoprotein-mediated viral infection. Journal of virology. 2004 Academic Article GET IT
Times cited: 319
Selection of functional 5' cis-acting elements promoting efficient sindbis virus genome replication. Journal of virology. 2004 Academic Article GET IT
Times cited: 59
Hepatitis C virus replicons finally get to second base. Gastroenterology. 2003 Editorial Article GET IT
Times cited: 2
Expression of the zinc-finger antiviral protein inhibits alphavirus replication. Journal of virology. 2003 Academic Article GET IT
Times cited: 297
HCV persistence and immune evasion in the absence of memory T cell help. Science (New York, N.Y.). 2003 Academic Article GET IT
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Presence of functional dendritic cells in patients chronically infected with hepatitis C virus. Blood. 2003 Academic Article GET IT
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Evasive maneuvers by hepatitis C virus. Hepatology (Baltimore, Md.). 2003 Article GET IT
Development and application of a reverse genetics system for Japanese encephalitis virus. Journal of virology. 2003 Academic Article GET IT
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Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles. Proceedings of the National Academy of Sciences of the United States of America. 2003 Academic Article GET IT
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A stable full-length yellow fever virus cDNA clone and the role of conserved RNA elements in flavivirus replication. The Journal of general virology. 2003 Academic Article GET IT
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Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication. Journal of virology. 2003 Academic Article GET IT
Times cited: 156
Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR. Journal of virology. 2003 Academic Article GET IT
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Kinetics of CD4+ and CD8+ memory T-cell responses during hepatitis C virus rechallenge of previously recovered chimpanzees. Journal of virology. 2003 Academic Article GET IT
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Accumulation of B lymphocytes with a naive, resting phenotype in a subset of hepatitis C patients. Journal of immunology (Baltimore, Md. : 1950). 2003 Academic Article GET IT
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Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture. Journal of virology. 2003 Academic Article GET IT
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Hepatitis C virus RNA synthesis in a cell-free system isolated from replicon-containing hepatoma cells. Journal of virology. 2003 Academic Article GET IT
Times cited: 73
New therapies on the horizon for hepatitis C: are we close?. Clinics in liver disease. 2003 Information Resource GET IT
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Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proceedings of the National Academy of Sciences of the United States of America. 2002 Academic Article GET IT
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Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. Journal of virology. 2002 Academic Article GET IT
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Roles of nonstructural protein nsP2 and Alpha/Beta interferons in determining the outcome of Sindbis virus infection. Journal of virology. 2002 Academic Article GET IT
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Interaction between hepatitis C virus proteins and host cell factors. Current opinion in microbiology. 2002 Information Resource GET IT
Characterization of vesicular stomatitis virus recombinants that express and incorporate high levels of hepatitis C virus glycoproteins. Journal of virology. 2002 Academic Article GET IT
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Previously infected and recovered chimpanzees exhibit rapid responses that control hepatitis C virus replication upon rechallenge. Journal of virology. 2002 Academic Article GET IT
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Molecular and immunological significance of chimpanzee major histocompatibility complex haplotypes for hepatitis C virus immune response and vaccination studies. Journal of virology. 2002 Academic Article GET IT
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Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles. Journal of virology. 2002 Academic Article GET IT
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RNAi targeting an animal virus: news from the front. Molecular cell. 2002 Information Resource GET IT
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Hepatitis C virus cell culture replication systems: their potential use for the development of antiviral therapies. Current opinion in infectious diseases. 2001 Information Resource GET IT
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Isolation and characterization of noncytopathic pestivirus mutants reveals a role for nonstructural protein NS4B in viral cytopathogenicity. Journal of virology. 2001 Academic Article GET IT
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Efficient translation initiation is required for replication of bovine viral diarrhea virus subgenomic replicons. Journal of virology. 2001 Academic Article GET IT
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Is CD81 the key to hepatitis C virus entry?. Hepatology (Baltimore, Md.). 1999 Information Resource GET IT
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Continuous human cell lines inducibly expressing hepatitis C virus structural and nonstructural proteins. Hepatology (Baltimore, Md.). 1998 Academic Article GET IT
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Expression of the structural proteins of dengue 2 virus and yellow fever virus by recombinant vaccinia viruses. Archives of virology. 1990 Academic Article GET IT
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Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions. Journal of virology. 1989 Academic Article GET IT
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Mapping of RNA- temperature-sensitive mutants of Sindbis virus: complementation group F mutants have lesions in nsP4. Journal of virology. 1989 Academic Article GET IT
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Nonstructural proteins nsP3 and nsP4 of Ross River and O'Nyong-nyong viruses: sequence and comparison with those of other alphaviruses. Virology. 1988 Academic Article GET IT
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Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences. Journal of molecular biology. 1987 Academic Article GET IT
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Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it. Proceedings of the National Academy of Sciences of the United States of America. 1987 Academic Article GET IT
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Partial N-terminal amino acid sequences of three nonstructural proteins of two flaviviruses. Virology. 1986 Academic Article GET IT
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Sindbis virus mutant ts20 of complementation group E contains a lesion in glycoprotein E2. Virology. 1986 Academic Article GET IT
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Partial nucleotide sequence of the Murray Valley encephalitis virus genome. Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins. Journal of molecular biology. 1986 Academic Article GET IT
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Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions. Journal of virology. 1985 Academic Article GET IT
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Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution. Science (New York, N.Y.). 1985 Academic Article GET IT
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Biochemical studies of the maturation of the small Sindbis virus glycoprotein E3. Virology. 1984 Academic Article GET IT
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Complete nucleotide sequence of the genomic RNA of Sindbis virus. Virology. 1984 Academic Article GET IT
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Ross River virus 26 s RNA: complete nucleotide sequence and deduced sequence of the encoded structural proteins. Virology. 1983 Academic Article GET IT
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Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA. Proceedings of the National Academy of Sciences of the United States of America. 1982 Academic Article GET IT
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The N-terminus of PE2 in Sindbis virus-infected cells. Virology. 1982 Academic Article GET IT
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Association of sindbis virion glycoproteins and their precursors. Journal of molecular biology. 1982 Academic Article GET IT
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Isolation and characterization of the hydrophobic COOH-terminal domains of the sindbis virion glycoproteins. Journal of molecular biology. 1982 Academic Article GET IT
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Synthesis, cleavage and sequence analysis of DNA complementary to the 26 S messenger RNA of Sindbis virus. Journal of molecular biology. 1981 Academic Article GET IT
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Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins. Proceedings of the National Academy of Sciences of the United States of America. 1981 Academic Article GET IT
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Background

education and training

Ph.D., California Institute of Technology 1981
B.S., University of California, Davis 1974

Contact

full name

Charles M. Rice

VIVO Weill Cornell Medical College

Charles M. Rice Adjunct Professor of Virology in Medicine

Publications

selected publications

Background

education and training

Contact

full name

Phone

Publications

selected publications

Background

education and training

Contact

full name