selected publications
- In vivo brain estrogen receptor density by neuroendocrine aging and relationships with cognition and symptomatology. Scientific reports. 2024 Academic Article GET IT
- Safety and efficacy of cerliponase alfa in children with neuronal ceroid lipofuscinosis type 2 (CLN2 disease): an open-label extension study. The Lancet. Neurology. 2024 Academic Article GET IT
- Positron Emission Tomography Quantitative Assessment of Off-Target Whole-Body Biodistribution of I-124-labeled Adeno-associated Virus Capsids Administered to Cerebral Spinal Fluid. Human gene therapy. 2023 Academic Article GET IT
- A Novel Hands-on Approach Towards Teaching Diagnostic Radiology Residents MRI Scanning and Physics. Academic radiology. 2023 Academic Article GET IT
- A pathway towards a two-dimensional bore-mounted volume body coil concept for ultra-high field MRI. NMR in biomedicine. 2022 Academic Article GET IT
- Use of small animal PET-CT imaging for in vivo assessment of tendon-to-bone healing: A pilot study. Journal of orthopaedic surgery (Hong Kong). 2022 Academic Article GET IT
- A 2D High-Pass Ladder RF Coil Architecture for UHF MRI. 2021 Conference Paper
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Safety of Direct Intraparenchymal AAVrh.10-Mediated Central Nervous System Gene Therapy for Metachromatic Leukodystrophy.
Human gene therapy.
2021
Academic Article
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Times cited: 23 -
Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2.
Science translational medicine.
2020
Academic Article
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Times cited: 47 -
Quantitative Whole-Body Imaging of I-124-Labeled Adeno-Associated Viral Vector Biodistribution in Nonhuman Primates.
Human gene therapy.
2020
Academic Article
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Times cited: 23 -
Untargeted Metabolite Profiling of Cerebrospinal Fluid Uncovers Biomarkers for Severity of Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2, Batten Disease).
Scientific reports.
2018
Academic Article
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Times cited: 20 -
Safe and stable noninvasive focal gene delivery to the mammalian brain following focused ultrasound.
Journal of neurosurgery.
2018
Academic Article
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Times cited: 33 -
Study of Intraventricular Cerliponase Alfa for CLN2 Disease.
The New England journal of medicine.
2018
Academic Article
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Times cited: 161 -
AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease.
Human gene therapy. Clinical development.
2018
Academic Article
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Times cited: 113 -
Clinical improvement associated with targeted interruption of the cerebellothalamic tract following MR-guided focused ultrasound for essential tremor.
Journal of neurosurgery.
2017
Academic Article
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Times cited: 48 -
Detection of Botulinum Toxin Muscle Effect in Humans Using Magnetic Resonance Imaging: A Qualitative Case Series.
PM & R : the journal of injury, function, and rehabilitation.
2017
Academic Article
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Times cited: 4 -
Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors.
Scientific reports.
2017
Academic Article
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Times cited: 18 -
Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma.
PloS one.
2016
Academic Article
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Times cited: 18 -
Magnetic resonance microscopy may enable distinction between normal histomorphological features and prostate cancer in the resected prostate gland.
BJU international.
2016
Academic Article
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Times cited: 3 -
Brain Region-Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease).
AJNR. American journal of neuroradiology.
2016
Academic Article
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Times cited: 19 -
Magnetic resonance advection imaging of cerebrovascular pulse dynamics.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2016
Academic Article
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Times cited: 5 -
The Potential of High Resolution Magnetic Resonance Microscopy in the Pathologic Analysis of Resected Breast and Lymph Tissue.
Scientific reports.
2015
Academic Article
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Times cited: 16 -
Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma.
Cancer gene therapy.
2014
Academic Article
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Times cited: 18 -
Characterization of bone perfusion by dynamic contrast-enhanced magnetic resonance imaging and positron emission tomography in the Dunkin-Hartley guinea pig model of advanced osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
2014
Academic Article
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Times cited: 21 -
Intra-arterial delivery of AAV vectors to the mouse brain after mannitol mediated blood brain barrier disruption.
Journal of controlled release : official journal of the Controlled Release Society.
2014
Academic Article
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Times cited: 74 -
proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus.
Cell reports.
2014
Academic Article
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Times cited: 237 -
Assessment of intervertebral disc degeneration based on quantitative magnetic resonance imaging analysis: an in vivo study.
Spine.
2014
Academic Article
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Times cited: 31 -
Cannulation of the internal carotid artery in mice: a novel technique for intra-arterial delivery of therapeutics.
Journal of neuroscience methods.
2013
Academic Article
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Times cited: 8 -
Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2013
Academic Article
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Times cited: 41 -
Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis.
Human gene therapy methods.
2012
Academic Article
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Times cited: 84 -
Assessment of disease severity in late infantile neuronal ceroid lipofuscinosis using multiparametric MR imaging.
AJNR. American journal of neuroradiology.
2012
Academic Article
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Times cited: 17 -
Orthotopic glioblastoma stem-like cell xenograft model in mice to evaluate intra-arterial delivery of bevacizumab: from bedside to bench.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.
2012
Academic Article
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Times cited: 29 -
High-resolution magnetic resonance imaging of prostatectomy specimens: a promising tool for virtual histology.
European urology.
2012
Article
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Times cited: 5 -
Intra-arterial bevacizumab with blood brain barrier disruption in a glioblastoma xenograft model.
Journal of experimental therapeutics & oncology.
2012
Academic Article
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Times cited: 4 -
Behavioral and neural properties of social reinforcement learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2011
Academic Article
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Times cited: 142 -
Image-based tissue engineering of a total intervertebral disc implant for restoration of function to the rat lumbar spine.
NMR in biomedicine.
2011
Academic Article
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Times cited: 34 -
Dissociations between behavioural and functional magnetic resonance imaging-based evaluations of cognitive function after brain injury.
Brain : a journal of neurology.
2011
Academic Article
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Times cited: 241 -
A genetic variant BDNF polymorphism alters extinction learning in both mouse and human.
Science (New York, N.Y.).
2010
Academic Article
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Times cited: 504 -
The development of stimulus-specific auditory responses requires song exposure in male but not female zebra finches.
Developmental neurobiology.
2010
Academic Article
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Times cited: 30 -
Enhanced antimyeloma cytotoxicity by the combination of arsenic trioxide and bortezomib is further potentiated by p38 MAPK inhibition.
Leukemia research.
2009
Academic Article
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Times cited: 38 -
Subchondral fluid dynamics in a model of osteoarthritis: use of dynamic contrast-enhanced magnetic resonance imaging.
Osteoarthritis and cartilage.
2009
Academic Article
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Times cited: 46 -
Novel microcatheters for selective intra-arterial injection of fluid in the rat brain.
AJNR. American journal of neuroradiology.
2009
Academic Article
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Times cited: 8 -
Quantitative intact specimen magnetic resonance microscopy at 3.0 T.
Magnetic resonance imaging.
2009
Academic Article
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Times cited: 6 - Classical Möbius-ring resonators exhibit fermion-boson rotational symmetry. Physical review letters. 2008 Academic Article GET IT
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The bivalent side of the nucleus accumbens.
NeuroImage.
2008
Academic Article
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Times cited: 96 -
Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA.
Human gene therapy.
2008
Academic Article
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Times cited: 295 -
P38 MAPK inhibition enhancing ATO-induced cytotoxicity against multiple myeloma cells.
British journal of haematology.
2008
Academic Article
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Times cited: 44 -
Neurological deterioration in late infantile neuronal ceroid lipofuscinosis.
Neurology.
2007
Academic Article
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Times cited: 69 -
Assessing disease severity in late infantile neuronal ceroid lipofuscinosis using quantitative MR diffusion-weighted imaging.
AJNR. American journal of neuroradiology.
2007
Academic Article
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Times cited: 25 -
Investigation of the role of the base in the synthesis of [18F]FLT.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.
2007
Academic Article
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Times cited: 28 -
Functional MRI of the zebra finch brain during song stimulation suggests a lateralized response topography.
Proceedings of the National Academy of Sciences of the United States of America.
2007
Academic Article
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Times cited: 69 -
High-pass two-dimensional ladder network resonators for magnetic resonance imaging.
IEEE transactions on bio-medical engineering.
2006
Academic Article
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Times cited: 6 -
Monitoring the effects of BCNU chemotherapy Wafers (Gliadel) in glioblastoma multiforme with proton magnetic resonance spectroscopic imaging at 3.0 Tesla.
Journal of neuro-oncology.
2006
Academic Article
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Times cited: 20 -
Possible axonal regrowth in late recovery from the minimally conscious state.
The Journal of clinical investigation.
2006
Academic Article
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Times cited: 288 -
In vivo 31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial.
NMR in biomedicine.
2006
Academic Article
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Times cited: 41 -
Fiber tracking in the cervical spine and inferior brain regions with reversed gradient diffusion tensor imaging.
Magnetic resonance imaging.
2006
Academic Article
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Times cited: 38 -
Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders.
Human gene therapy.
2005
Review
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Times cited: 27 -
Imaging therapeutic response in human bone marrow using rapid whole-body MRI.
Magnetic resonance in medicine.
2004
Academic Article
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Times cited: 63 -
Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis.
Human gene therapy.
2004
Academic Article
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Times cited: 100 -
A stereotactic method for the three-dimensional registration of multi-modality biologic images in animals: NMR, PET, histology, and autoradiography.
Medical physics.
2003
Academic Article
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Times cited: 47 -
MRI of occult breast carcinoma in a high-risk population.
AJR. American journal of roentgenology.
2003
Academic Article
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Times cited: 283 -
Osteogenic and Ewing sarcomas: estimation of necrotic fraction during induction chemotherapy with dynamic contrast-enhanced MR imaging.
Radiology.
2003
Academic Article
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Times cited: 107 -
In vivo multiple-mouse imaging at 1.5 T.
Magnetic resonance in medicine.
2003
Academic Article
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Times cited: 44 -
Breast lesions detected on MR imaging: features and positive predictive value.
AJR. American journal of roentgenology.
2002
Academic Article
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Times cited: 250 -
Preoperative MR imaging-guided needle localization of breast lesions.
AJR. American journal of roentgenology.
2002
Academic Article
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Times cited: 106 -
An apparatus for MR-guided breast lesion localization and core biopsy: design and preliminary results.
Journal of magnetic resonance imaging : JMRI.
2001
Academic Article
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Times cited: 23 -
Observer variability and applicability of BI-RADS terminology for breast MR imaging: invasive carcinomas as focal masses.
AJR. American journal of roentgenology.
2001
Academic Article
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Times cited: 55 -
Bone marrow segmentation in leukemia using diffusion and T (2) weighted echo planar magnetic resonance imaging.
NMR in biomedicine.
2000
Academic Article
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Times cited: 34 -
The in vivo effect of bryostatin-1 on paclitaxel-induced tumor growth, mitotic entry, and blood flow.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2000
Academic Article
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Times cited: 57 -
An automated iterative algorithm for water and fat decomposition in three-point Dixon magnetic resonance imaging.
Medical physics.
1999
Academic Article
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Times cited: 8 -
Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo.
Cancer research.
1999
Academic Article
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Times cited: 149 -
A dual-tuned resonator for proton-decoupled phosphorus-31 chemical shift imaging of the brain.
Magnetic resonance in medicine.
1999
Academic Article
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Times cited: 8 -
Quantitative assessment of bone marrow hematopoiesis using parametric magnetic resonance imaging.
Magnetic resonance in medicine.
1998
Academic Article
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Times cited: 19 -
Evaluation of chemotherapy and radiation enhancement and 31P NMR spectral changes induced by biochemical modulation.
Cancer investigation.
1997
Academic Article
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Times cited: 2 -
Sensitivity-enhanced echo-planar MRI at 1.5T using a 5 x 5 mesh dome resonator.
Magnetic resonance in medicine.
1996
Academic Article
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Times cited: 7 -
13C and 31P NMR investigation of effect of 6-aminonicotinamide on metabolism of RIF-1 tumor cells in vitro.
The Journal of biological chemistry.
1996
Academic Article
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Times cited: 33 -
Spatial mapping of the percentage cellularity in human bone marrow using magnetic resonance imaging.
Medical physics.
1996
Academic Article
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Times cited: 14 - Intracavitary birdcage resonator: applications to the human prostate. Journal of magnetic resonance imaging : JMRI. 1995 Academic Article GET IT
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A 3 x 3 mesh two-dimensional ladder network resonator for MRI of the human head.
Journal of magnetic resonance. Series B.
1995
Academic Article
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Times cited: 7 - In vitro and in vivo 31P nuclear magnetic resonance measurements of metabolic changes post radiation. Cancer research. 1995 Academic Article GET IT
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Resolution enhanced NMR spectroscopy in biological systems via magnetic susceptibility matched sample immersion chambers.
Magnetic resonance in medicine.
1993
Academic Article
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Times cited: 28 -
Iododeoxyuridine uptake and retention as a measure of tumor growth.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1993
Academic Article
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Times cited: 56 -
A birdcage resonator for intracavitary MR imaging.
Magnetic resonance imaging.
1993
Academic Article
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Times cited: 4 -
Quantitation of total metastatic tumor volume in the rat liver: correlation of MR and histologic measurements.
Journal of magnetic resonance imaging : JMRI.
1992
Academic Article
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Times cited: 12 -
In vivo measurements of bone marrow cellularity using volume-localized proton NMR spectroscopy.
Magnetic resonance in medicine.
1991
Academic Article
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Times cited: 62 -
An analysis of the intrinsic resonance offset dependence of magnetization generated by stimulated echo pulse sequences for noncoupled spins.
Magnetic resonance imaging.
1991
Academic Article
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Times cited: 8 -
Changes in radiation sensitization induced by Fluosol-DA as measured by 31P nuclear magnetic resonance spectroscopy.
Cancer research.
1990
Academic Article
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Times cited: 19 -
Doubly tuned solenoidal resonators for small animal imaging and spectroscopy at 1.5 Tesla.
Magnetic resonance imaging.
1989
Academic Article
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Times cited: 13 -
Nuclear magnetic resonance: principles and applications to pathology.
Clinics in laboratory medicine.
1988
Information Resource
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Times cited: 1 -
The effect of angular spread on the intensity distribution of arbitrarily shaped electron beams.
Medical physics.
1988
Academic Article
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Times cited: 4 - Magnetic moments of the (3/2)1- and (5/2)1- states in 107,109Ag. Physical review. C, Nuclear physics. 1986 Academic Article GET IT