Nuclear magnetic resonance: principles and applications to pathology.

Overview

Nuclear magnetic resonance is a valuable tool in the analytical chemistry laboratory. Recent technological advances have increased its sensitivity so that it can be used to detect millimolar and submillimolar quantities. It can be used to analyze body fluids for different metabolites and drugs. The technique is not destructive; therefore, it can be used as an initial screening tool, which can guide the subsequent selection of more sensitive analytical techniques for more definitive quantitation.