selected publications
- Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT
- Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.). 2024 Academic Article GET IT
- LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase. 2023 GET IT
- FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS. 2023 GET IT
- Generation of precision preclinical cancer models using regulated in vivo base editing. Nature biotechnology. 2023 Academic Article GET IT
- LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma. Cancer discovery. 2023 Academic Article GET IT
- Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis. Cancer research. 2022 Academic Article GET IT
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Role of mTOR As an Essential Kinase in SCLC.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2020
Academic Article
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Times cited: 13 -
Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 55 -
Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer.
Cancer research.
2017
Academic Article
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Times cited: 85 -
Histone Code Aberrancies in Small Cell Lung Cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2017
Editorial Article
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Times cited: 2 -
Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.
Cancer cell.
2017
Academic Article
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Times cited: 369 -
Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies.
Cell reports.
2016
Academic Article
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Times cited: 419 -
Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis.
PloS one.
2016
Academic Article
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Times cited: 47 -
PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
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Times cited: 259 -
P-selectin is a nanotherapeutic delivery target in the tumor microenvironment.
Science translational medicine.
2016
Academic Article
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Times cited: 156 -
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer.
The Journal of clinical investigation.
2016
Academic Article
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Times cited: 338 -
DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.
Oncogene.
2015
Academic Article
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Times cited: 185 -
Differential dynamics of extracellular and cytoplasmic domains in denatured States of rhodopsin.
Biochemistry.
2014
Academic Article
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Times cited: 5 -
Rapamycin rescues ABT-737 efficacy in small cell lung cancer.
Cancer research.
2014
Academic Article
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Times cited: 50 -
ERK phosphorylation is predictive of resistance to IGF-1R inhibition in small cell lung cancer.
Molecular cancer therapeutics.
2013
Academic Article
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Times cited: 31 -
Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer.
Molecular cancer.
2013
Academic Article
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Times cited: 43 -
Differential coupling of the human cannabinoid receptors hCB1R and hCB2R to the G-protein G(alpha)i2beta1gamma2.
Neuroscience letters.
2008
Academic Article
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Times cited: 11