Gardner, Eric

Publications

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selected publications

Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.). 2024 Academic Article GET IT
LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase. 2023 GET IT
FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS. 2023 GET IT
Generation of precision preclinical cancer models using regulated in vivo base editing. Nature biotechnology. 2023 Academic Article GET IT
LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma. Cancer discovery. 2023 Academic Article GET IT
Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis. Cancer research. 2022 Academic Article GET IT
Role of mTOR As an Essential Kinase in SCLC. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2020 Academic Article GET IT
Times cited: 14
Structural and Functional Consequences of the Weak Binding of Chlorin e6 to Bovine Rhodopsin. Photochemistry and photobiology. 2019 Academic Article GET IT
Times cited: 3
Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 56
Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer. Cancer research. 2017 Academic Article GET IT
Times cited: 86
Histone Code Aberrancies in Small Cell Lung Cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2017 Editorial Article GET IT
Times cited: 2
Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis. Cancer cell. 2017 Academic Article GET IT
Times cited: 373
Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies. Cell reports. 2016 Academic Article GET IT
Times cited: 426
Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis. PloS one. 2016 Academic Article GET IT
Times cited: 47
PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 263
P-selectin is a nanotherapeutic delivery target in the tumor microenvironment. Science translational medicine. 2016 Academic Article GET IT
Times cited: 158
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. The Journal of clinical investigation. 2016 Academic Article GET IT
Times cited: 338
DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2. Oncogene. 2015 Academic Article GET IT
Times cited: 185
Differential dynamics of extracellular and cytoplasmic domains in denatured States of rhodopsin. Biochemistry. 2014 Academic Article GET IT
Times cited: 5
Rapamycin rescues ABT-737 efficacy in small cell lung cancer. Cancer research. 2014 Academic Article GET IT
Times cited: 50
ERK phosphorylation is predictive of resistance to IGF-1R inhibition in small cell lung cancer. Molecular cancer therapeutics. 2013 Academic Article GET IT
Times cited: 31
Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Molecular cancer. 2013 Academic Article GET IT
Times cited: 43
Differential coupling of the human cannabinoid receptors hCB1R and hCB2R to the G-protein G(alpha)i2beta1gamma2. Neuroscience letters. 2008 Academic Article GET IT
Times cited: 11

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Research

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Funding awarded

Studies of the initiation and progression of small cell lung cancer using cells derived by differentiation from human pluripotent stem cells awarded by National Cancer Institute Key Personnel 2018 - 2025

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Background

education and training

Ph.D., The Johns Hopkins University School of Medicine 2017
Pharm.D., University of Pittsburgh School of Medicine 2011

Contact

full name

Eric Gardner

primary email

eeg2001@med.cornell.edu

webpage

https://vivo.med.cornell.edu/individual/n7336 (no url provided for link)

phone

6469626966
6469626966
6469626966

Identity

eRA Commons ID

GARDNEREE

VIVO Weill Cornell Medical College

Eric Gardner Postdoctoral Associate in Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

phone

Identity

eRA Commons ID

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

phone

Identity

eRA Commons ID