selected publications
- Stress response regulation of mRNA translation: Implications for antioxidant enzyme expression in cancer. Proceedings of the National Academy of Sciences of the United States of America. 2024 Review GET IT
- Selenocysteine tRNA methylation promotes oxidative stress resistance in melanoma metastasis. Nature cancer. 2024 Academic Article GET IT
- Decoding the role of tRNA modifications in cancer progression. Current opinion in genetics & development. 2024 Review GET IT
- Transcriptional Isoforms of NAD+ kinase regulate oxidative stress resistance and melanoma metastasis. Redox biology. 2024 Academic Article GET IT
- Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication. Science signaling. 2022 Academic Article GET IT
- A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation. Cell reports. 2022 Academic Article GET IT
- The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage. Cell metabolism. 2021 Academic Article GET IT
- NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell reports. 2021 Academic Article GET IT
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An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants.
Cancer discovery.
2020
Academic Article
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Times cited: 67 -
Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.
Nature.
2017
Academic Article
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Times cited: 397 -
Oxidative stress inhibits distant metastasis by human melanoma cells.
Nature.
2015
Academic Article
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Times cited: 938 -
Human melanoma metastasis in NSG mice correlates with clinical outcome in patients.
Science translational medicine.
2012
Academic Article
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Times cited: 84 -
Absence of functional LIN28B mutations in a large cohort of patients with idiopathic central precocious puberty.
Hormone research in paediatrics.
2012
Academic Article
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Times cited: 31 -
Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7).
RNA (New York, N.Y.).
2012
Academic Article
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Times cited: 174 -
Cancer stem cells: impact, heterogeneity, and uncertainty.
Cancer cell.
2012
Information Resource
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Times cited: 957 -
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.
Cell.
2011
Academic Article
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Times cited: 511 -
Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells.
Nature structural & molecular biology.
2009
Academic Article
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Times cited: 425 -
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.
The Journal of biological chemistry.
2008
Academic Article
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Times cited: 274