Altamirano, Francisco

Publications

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selected publications

Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response. 2024 GET IT
Folate as a potential treatment for lethal ventricular arrhythmias in TANGO2-deficiency disorder. JCI insight. 2024 Academic Article GET IT
IRE1α Mediates the Hypertrophic Growth of Cardiomyocytes Through Facilitating the Formation of Initiation Complex to Promote the Translation of TOP-Motif Transcripts. Circulation. 2024 Academic Article GET IT
Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization. Cardiovascular research. 2024 Academic Article GET IT
Bridging the Translational Gap in Heart Failure Research: Using Human iPSC-derived Cardiomyocytes to Accelerate Therapeutic Insights. Methodist DeBakey cardiovascular journal. 2023 Review GET IT
Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization. 2023 GET IT
Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy. PloS one. 2021 Academic Article GET IT
Polycystin-1 regulates cardiomyocyte mitophagy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021 Academic Article GET IT
Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury. Circulation research. 2021 Academic Article GET IT
Times cited: 31
NAD⁺ Repletion Reverses Heart Failure With Preserved Ejection Fraction. Circulation research. 2021 Academic Article GET IT
Times cited: 108
Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction. Nature communications. 2021 Academic Article GET IT
Times cited: 79
Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome to Regulate Cardiac Function. Circulation. 2020 Academic Article GET IT
Times cited: 51
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1. Autophagy. 2020 Academic Article GET IT
Times cited: 32
FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth. Nature communications. 2020 Academic Article GET IT
Times cited: 30
Remodeling of substrate consumption in the murine sTAC model of heart failure. Journal of molecular and cellular cardiology. 2019 Academic Article GET IT
Times cited: 13
Polycystin-1 Assembles With Kv Channels to Govern Cardiomyocyte Repolarization and Contractility. Circulation. 2019 Academic Article GET IT
Times cited: 27
Fibroblast Primary Cilia Are Required for Cardiac Fibrosis. Circulation. 2019 Academic Article GET IT
Times cited: 96
Nitrosative stress drives heart failure with preserved ejection fraction. Nature. 2019 Academic Article GET IT
Times cited: 525
Is malignant hyperthermia associated with hyperglycaemia?. British journal of anaesthesia. 2018 Letter GET IT
Times cited: 9
Polycystin-2-dependent control of cardiomyocyte autophagy. Journal of molecular and cellular cardiology. 2018 Academic Article GET IT
Times cited: 13
Down Syndrome Critical Region 1 Gene, Rcan1, Helps Maintain a More Fused Mitochondrial Network. Circulation research. 2018 Academic Article GET IT
Times cited: 52
Dysregulation of Intracellular Ca²⁺ in Dystrophic Cortical and Hippocampal Neurons. Molecular neurobiology. 2016 Academic Article GET IT
Times cited: 13
Whole Body Periodic Acceleration Improves Muscle Recovery after Eccentric Exercise. Medicine and science in sports and exercise. 2016 Academic Article GET IT
Times cited: 10
NOX2 Inhibition Impairs Early Muscle Gene Expression Induced by a Single Exercise Bout. Frontiers in physiology. 2016 Academic Article GET IT
Times cited: 45
Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death. Biochimica et biophysica acta. 2016 Review GET IT
Times cited: 25
Cardioprotection in ischaemia-reperfusion injury: novel mechanisms and clinical translation. The Journal of physiology. 2015 Review GET IT
Times cited: 38
Antioxidant Properties of Whole Body Periodic Acceleration (pGz). PloS one. 2015 Academic Article GET IT
Times cited: 19
Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells. Biochimica et biophysica acta. 2015 Academic Article GET IT
Times cited: 61
Non-invasive technology that improves cardiac function after experimental myocardial infarction: Whole Body Periodic Acceleration (pGz). PloS one. 2015 Academic Article GET IT
Times cited: 9
Age-dependent changes in diastolic Ca(2+) and Na(+) concentrations in dystrophic cardiomyopathy: Role of Ca(2+) entry and IP3. Biochemical and biophysical research communications. 2014 Academic Article GET IT
Times cited: 33
Whole body periodic acceleration is an effective therapy to ameliorate muscular dystrophy in mdx mice. PloS one. 2014 Academic Article GET IT
Times cited: 20
Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle. The Journal of biological chemistry. 2014 Academic Article GET IT
Times cited: 23
Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice. Molecular and cellular biology. 2014 Academic Article GET IT
Times cited: 30
Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice. PloS one. 2013 Academic Article GET IT
Times cited: 44
Testosterone signals through mTOR and androgen receptor to induce muscle hypertrophy. Medicine and science in sports and exercise. 2013 Academic Article GET IT
Times cited: 83
Cav1.1 controls frequency-dependent events regulating adult skeletal muscle plasticity. Journal of cell science. 2013 Academic Article GET IT
Times cited: 41
Electrical stimuli release ATP to increase GLUT4 translocation and glucose uptake via PI3Kγ-Akt-AS160 in skeletal muscle cells. Diabetes. 2012 Academic Article GET IT
Times cited: 101
Increased resting intracellular calcium modulates NF-κB-dependent inducible nitric-oxide synthase gene expression in dystrophic mdx skeletal myotubes. The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 72
Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 76
Measurement of calcium release due to inositol trisphosphate receptors in skeletal muscle. Methods in molecular biology (Clifton, N.J.). 2012 Academic Article GET IT
Times cited: 4
Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway. The Journal of endocrinology. 2009 Academic Article GET IT
Times cited: 75
RpoS and RpoN are involved in the growth-dependent regulation of rfaH transcription and O antigen expression in Salmonella enterica serovar Typhi. Microbial pathogenesis. 2004 Academic Article GET IT
Times cited: 23

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Background

education and training

Ph.D., University of Chile (Chile) 2012
B.S., University of Chile (Chile) 2007

Contact

full name

Francisco Altamirano

primary email

faltamirano@houstonmethodist.org
fra4004@med.cornell.edu

mailing address

6565 Fannin Street,

F7-064 (Office)

Houston, TX 77030

US

VIVO Weill Cornell Medical College

Francisco Altamirano Assistant Professor of Molecular Biology in Cardiothoracic Surgery

Publications

selected publications

Background

education and training

Contact

full name

primary email

mailing address