selected publications
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Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury.
Communications biology.
2024
Academic Article
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Times cited: 1 - CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit. 2024 GET IT
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A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.
Developmental cell.
2023
Academic Article
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Times cited: 15 -
The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells.
JCI insight.
2023
Academic Article
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Times cited: 8 -
Hallmarks of CD8+ T cell dysfunction are established within hours of tumor antigen encounter before cell division.
Nature immunology.
2023
Academic Article
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Times cited: 62 -
Increased Primary Bile Acids with Ileocolonic Resection Impact Ileal Inflammation and Gut Microbiota in Inflammatory Bowel Disease.
Journal of Crohn's & colitis.
2023
Academic Article
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Times cited: 13 -
Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege.
The Journal of clinical investigation.
2023
Academic Article
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Times cited: 31 -
A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.
Nature cell biology.
2023
Academic Article
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Times cited: 42 - Cross-species single-cell comparison of systemic and cardiac inflammatory responses after cardiac injury. 2023 GET IT
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Activation of a transient progenitor state in the epicardium is required for zebrafish heart regeneration.
Nature communications.
2022
Academic Article
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Times cited: 24 -
SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells.
Nature communications.
2022
Academic Article
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Times cited: 21 -
Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nature medicine.
2022
Academic Article
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Times cited: 77 -
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion.
The Journal of experimental medicine.
2021
Academic Article
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Times cited: 86 -
An autoimmune stem-like CD8 T cell population drives type 1 diabetes.
Nature.
2021
Academic Article
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Times cited: 148 -
Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids.
Molecular psychiatry.
2021
Academic Article
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Times cited: 75 -
Hippocampal Transcriptome Changes After Subarachnoid Hemorrhage in Mice.
Frontiers in neurology.
2021
Academic Article
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Times cited: 5 -
Selective BCL-XL Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from Ex Vivo Reservoirs.
Journal of virology.
2021
Academic Article
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Times cited: 13 -
Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus.
Cell reports.
2020
Academic Article
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Times cited: 9 -
TOX is a critical regulator of tumour-specific T cell differentiation.
Nature.
2019
Academic Article
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Times cited: 765 -
Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.
Nature genetics.
2019
Academic Article
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Times cited: 88 -
Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation.
Nature structural & molecular biology.
2016
Academic Article
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Times cited: 10 -
deepTools2: a next generation web server for deep-sequencing data analysis.
Nucleic acids research.
2016
Academic Article
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Times cited: 4544 -
MOF-associated complexes ensure stem cell identity and Xist repression.
eLife.
2014
Academic Article
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Times cited: 76 -
deepTools: a flexible platform for exploring deep-sequencing data.
Nucleic acids research.
2014
Academic Article
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Times cited: 2192