selected publications
- CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit. 2024 GET IT
- A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas. Developmental cell. 2023 Academic Article GET IT
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The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells.
JCI insight.
2023
Academic Article
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Times cited: 6 - Hallmarks of CD8+ T cell dysfunction are established within hours of tumor antigen encounter before cell division. Nature immunology. 2023 Academic Article GET IT
- A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes. Nature cell biology. 2023 Academic Article GET IT
- Cross-species single-cell comparison of systemic and cardiac inflammatory responses after cardiac injury. 2023 GET IT
- Epsilon toxin-producing Clostridium perfringens colonize the MS gut and epsilon toxin overcomes immune privilege. The Journal of clinical investigation. 2023 Academic Article GET IT
- Activation of a transient progenitor state in the epicardium is required for zebrafish heart regeneration. Nature communications. 2022 Academic Article GET IT
- Increased Primary Bile Acids with Ileocolonic Resection Impact Ileal Inflammation and Gut Microbiota in Inflammatory Bowel Disease. Journal of Crohn's & colitis. 2022 Academic Article GET IT
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SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells.
Nature communications.
2022
Academic Article
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Times cited: 20 - Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA. Nature medicine. 2022 Academic Article GET IT
- TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion. The Journal of experimental medicine. 2021 Academic Article GET IT
- An autoimmune stem-like CD8 T cell population drives type 1 diabetes. Nature. 2021 Academic Article GET IT
- Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids. Molecular psychiatry. 2021 Academic Article GET IT
- Hippocampal Transcriptome Changes After Subarachnoid Hemorrhage in Mice. Frontiers in neurology. 2021 Academic Article GET IT
- Selective BCL-XL Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from Ex Vivo Reservoirs. Journal of virology. 2021 Academic Article GET IT
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Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus.
Cell reports.
2020
Academic Article
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Times cited: 9 -
TOX is a critical regulator of tumour-specific T cell differentiation.
Nature.
2019
Academic Article
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Times cited: 710 -
Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.
Nature genetics.
2019
Academic Article
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Times cited: 80 -
Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation.
Nature structural & molecular biology.
2016
Academic Article
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Times cited: 10 -
deepTools2: a next generation web server for deep-sequencing data analysis.
Nucleic acids research.
2016
Academic Article
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Times cited: 4001 -
MOF-associated complexes ensure stem cell identity and Xist repression.
eLife.
2014
Academic Article
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Times cited: 75 -
deepTools: a flexible platform for exploring deep-sequencing data.
Nucleic acids research.
2014
Academic Article
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Times cited: 1943