selected publications
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Effect of Osimertinib and Bevacizumab on Progression-Free Survival for Patients With Metastatic EGFR-Mutant Lung Cancers: A Phase 1/2 Single-Group Open-Label Trial.
JAMA oncology.
2020
Academic Article
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Times cited: 107 -
COVID-19 in patients with lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology.
2020
Academic Article
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Times cited: 199 -
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers.
Cancer discovery.
2020
Academic Article
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Times cited: 185 -
The Evolving Landscape of Resistance to Osimertinib.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2020
Editorial Article
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Times cited: 12 -
Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2019
Academic Article
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Times cited: 252 -
A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers.
Journal of the National Cancer Institute.
2019
Academic Article
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Times cited: 98 -
Severe immune-related adverse events are common with sequential PD-(L)1 blockade and osimertinib.
Annals of oncology : official journal of the European Society for Medical Oncology.
2019
Academic Article
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Times cited: 303 -
Exceptional responders with invasive mucinous adenocarcinomas: a phase 2 trial of bortezomib in patients with KRAS G12D-mutant lung cancers.
Cold Spring Harbor molecular case studies.
2019
Academic Article
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Times cited: 24 -
YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.
Proceedings of the National Academy of Sciences of the United States of America.
2018
Academic Article
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Times cited: 42 -
Sequencing Therapy for Genetically Defined Subgroups of Non-Small Cell Lung Cancer.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.
2018
Information Resource
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Times cited: 9 -
Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 205 -
Effects of Co-occurring Genomic Alterations on Outcomes in Patients with KRAS-Mutant Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
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Times cited: 327 -
A Phase I, Dose Escalation Study of Oral ASP8273 in Patients with Non-small Cell Lung Cancers with Epidermal Growth Factor Receptor Mutations.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
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Times cited: 20 -
Twice weekly pulse and daily continuous-dose erlotinib as initial treatment for patients with epidermal growth factor receptor-mutant lung cancers and brain metastases.
Cancer.
2017
Academic Article
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Times cited: 28 -
Phase 2 study of intermittent pulse dacomitinib in patients with advanced non-small cell lung cancers.
Lung cancer (Amsterdam, Netherlands).
2017
Academic Article
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Times cited: 7 -
Patterns of initial and intracranial failure in metastatic EGFR-mutant non-small cell lung cancer treated with erlotinib.
Lung cancer (Amsterdam, Netherlands).
2017
Academic Article
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Times cited: 43 -
Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies.
Cancer discovery.
2017
Academic Article
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Times cited: 498 -
Phase 1 study of twice weekly pulse dose and daily low-dose erlotinib as initial treatment for patients with EGFR-mutant lung cancers.
Annals of oncology : official journal of the European Society for Medical Oncology.
2017
Academic Article
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Times cited: 40 -
Serum Biomarkers Associated with Clinical Outcomes Fail to Predict Brain Metastases in Patients with Stage IV Non-Small Cell Lung Cancers.
PloS one.
2016
Academic Article
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Times cited: 17 -
Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Academic Article
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Times cited: 321 -
Epidermal growth factor receptor exon 20 insertions in advanced lung adenocarcinomas: Clinical outcomes and response to erlotinib.
Cancer.
2015
Academic Article
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Times cited: 186 -
EGFR: The Paradigm of an Oncogene-Driven Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Academic Article
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Times cited: 74 -
Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping.
Cancer discovery.
2015
Academic Article
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Times cited: 492 -
Phase I/II Study of HSP90 Inhibitor AUY922 and Erlotinib for EGFR-Mutant Lung Cancer With Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2015
Academic Article
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Times cited: 90 -
Differences in the survival of patients with recurrent versus de novo metastatic KRAS-mutant and EGFR-mutant lung adenocarcinomas.
Cancer.
2015
Academic Article
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Times cited: 14 -
Prognostic impact of KRAS mutation subtypes in 677 patients with metastatic lung adenocarcinomas.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2015
Academic Article
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Times cited: 115 -
Small-cell lung cancers in patients who never smoked cigarettes.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2014
Academic Article
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Times cited: 112 -
Erlotinib versus radiation therapy for brain metastases in patients with EGFR-mutant lung adenocarcinoma.
International journal of radiation oncology, biology, physics.
2014
Academic Article
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Times cited: 85 -
Poor response to erlotinib in patients with tumors containing baseline EGFR T790M mutations found by routine clinical molecular testing.
Annals of oncology : official journal of the European Society for Medical Oncology.
2014
Academic Article
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Times cited: 178 -
Targeted therapies: Afatinib--new therapy option for EGFR-mutant lung cancer.
Nature reviews. Clinical oncology.
2013
Article
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Times cited: 81 -
Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2013
Academic Article
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Times cited: 2103 -
Local therapy with continued EGFR tyrosine kinase inhibitor therapy as a treatment strategy in EGFR-mutant advanced lung cancers that have developed acquired resistance to EGFR tyrosine kinase inhibitors.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2013
Academic Article
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Times cited: 292 -
Second-generation epidermal growth factor receptor tyrosine kinase inhibitors in lung cancers.
Journal of the National Comprehensive Cancer Network : JNCCN.
2013
Academic Article
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Times cited: 68 - Who should receive EGFR tyrosine-kinase inhibitors?. The Lancet. Oncology. 2012 Article GET IT