Dittman, Jeremy

Publications

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selected publications

Complexin gains effective access to the assembling SNAREs via its membrane-binding C-terminal domain. The Journal of physiology. 2025 Academic Article GET IT
Strength in numbers: vesicle priming states and the math of plasticity. The Journal of physiology. 2025 Academic Article GET IT
Taking a closer look at the synapse. Proceedings of the National Academy of Sciences of the United States of America. 2024 Comment GET IT
Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase. Nature communications. 2023 Academic Article GET IT
Membrane-mediated protein interactions drive membrane protein organization. Nature communications. 2022 Academic Article GET IT
Control of Gα_q signaling dynamics and GPCR cross-talk by GRKs. Science advances. 2022 Academic Article GET IT
Perforin-2 clockwise hand-over-hand pre-pore to pore transition mechanism. Nature communications. 2022 Academic Article GET IT
Complexin membrane interactions: implications for synapse evolution and function. Journal of molecular biology. 2022 Review GET IT
A unique C2 domain at the C terminus of Munc13 promotes synaptic vesicle priming. Proceedings of the National Academy of Sciences of the United States of America. 2021 Academic Article GET IT
Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors. Cell reports. 2020 Academic Article GET IT
Times cited: 51
The control of release probability at nerve terminals. Nature reviews. Neuroscience. 2019 Information Resource GET IT
Times cited: 24
Unc13: a multifunctional synaptic marvel. Current opinion in neurobiology. 2019 Information Resource GET IT
Times cited: 39
Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones. Nature communications. 2018 Academic Article GET IT
Times cited: 65
Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation. PLoS biology. 2018 Academic Article GET IT
Times cited: 107
A C1-C2 Module in Munc13 Inhibits Calcium-Dependent Neurotransmitter Release. Neuron. 2017 Academic Article GET IT
Times cited: 50
Evolutionary Divergence of the C-terminal Domain of Complexin Accounts for Functional Disparities between Vertebrate and Invertebrate Complexins. Frontiers in molecular neuroscience. 2017 Academic Article GET IT
Times cited: 23
Unique Structural Features of Membrane-Bound C-Terminal Domain Motifs Modulate Complexin Inhibitory Function. Frontiers in molecular neuroscience. 2017 Academic Article GET IT
Times cited: 24
Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 80
Downregulation of a GPCR by β-Arrestin2-Mediated Switch from an Endosomal to a TGN Recycling Pathway. Cell reports. 2016 Academic Article GET IT
Times cited: 41
Speed Limits for Nonvesicular Intracellular Sterol Transport. Trends in biochemical sciences. 2016 Information Resource GET IT
Times cited: 51
Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants. Nature communications. 2016 Academic Article GET IT
Times cited: 51
Synaptic activity regulates the abundance and binding of complexin. Biophysical journal. 2015 Academic Article GET IT
Times cited: 8
The accessory helix of complexin functions by stabilizing central helix secondary structure. eLife. 2014 Academic Article GET IT
Times cited: 34
Constitutive phospholipid scramblase activity of a G protein-coupled receptor. Nature communications. 2014 Academic Article GET IT
Times cited: 99
Membrane curvature sensing by the C-terminal domain of complexin. Nature communications. 2014 Academic Article GET IT
Times cited: 66
Synaptic vesicles position complexin to block spontaneous fusion. Neuron. 2013 Academic Article GET IT
Times cited: 73
Osh proteins regulate membrane sterol organization but are not required for sterol movement between the ER and PM. Traffic (Copenhagen, Denmark). 2011 Academic Article GET IT
Times cited: 110
Complexin has opposite effects on two modes of synaptic vesicle fusion. Current biology : CB. 2011 Academic Article GET IT
Times cited: 118
Endophilin functions as a membrane-bending molecule and is delivered to endocytic zones by exocytosis. Cell. 2010 Academic Article GET IT
Times cited: 100
Molecular circuitry of endocytosis at nerve terminals. Annual review of cell and developmental biology. 2009 Information Resource GET IT
Times cited: 176
Worm watching: imaging nervous system structure and function in Caenorhabditis elegans. Advances in genetics. 2009 Information Resource GET IT
Times cited: 5
Behavioral impact of neurotransmitter-activated G-protein-coupled receptors: muscarinic and GABAB receptors regulate Caenorhabditis elegans locomotion. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Academic Article GET IT
Times cited: 66
Factors regulating the abundance and localization of synaptobrevin in the plasma membrane. Proceedings of the National Academy of Sciences of the United States of America. 2006 Academic Article GET IT
Times cited: 117
Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans. Neuron. 2002 Academic Article GET IT
Times cited: 224
Interplay between facilitation, depression, and residual calcium at three presynaptic terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2000 Academic Article GET IT
Times cited: 425
Calcium dependence and recovery kinetics of presynaptic depression at the climbing fiber to Purkinje cell synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1998 Academic Article GET IT
Times cited: 335
Mechanism and kinetics of heterosynaptic depression at a cerebellar synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1997 Academic Article GET IT
Times cited: 122
Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1996 Academic Article GET IT
Times cited: 258
Shaker potassium channel gating. II: Transitions in the activation pathway. The Journal of general physiology. 1994 Academic Article GET IT
Times cited: 286

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Research

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missing activity Principal Investigator 2020 - 2026

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Background

education and training

M.D., Ph.D., Harvard Medical School 2000
B.S., Stanford University 1992

Contact

full name

Jeremy Dittman

primary email

jed2019@med.cornell.edu

webpage

https://vivo.med.cornell.edu/individual/n22671 (no url provided for link)

VIVO Weill Cornell Medical College

Jeremy Dittman Associate Professor

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage