Rodriguez Alcazar, Juan

Publications

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NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Academic Article GET IT
Times cited: 11
Type I IFN drives unconventional IL-1β secretion in lupus monocytes. Immunity. 2024 Academic Article GET IT
Times cited: 22
Ragas: integration and enhanced visualization for single cell subcluster analysis. Bioinformatics (Oxford, England). 2024 Academic Article GET IT
Times cited: 2
Peroxisome deficiency underlies failures in hepatic immune cell development and antigen presentation in a severe Zellweger disease model. Cell reports. 2024 Academic Article GET IT
Times cited: 6
An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes. 2023 GET IT
ATP-binding and hydrolysis of human NLRP3. Communications biology. 2022 Academic Article GET IT
Times cited: 44
Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation. Science advances. 2022 Academic Article GET IT
Times cited: 50
Alternative splicing regulates stochastic NLRP3 activity. Nature communications. 2019 Academic Article GET IT
Times cited: 56
Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1β Inflammation in Human Macrophages. Journal of immunology (Baltimore, Md. : 1950). 2018 Academic Article GET IT
Times cited: 61
Assembly and regulation of ASC specks. Cellular and molecular life sciences : CMLS. 2016 Review GET IT
Times cited: 118

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Co-investigator Network

Immune Cells and Secretory Pathways Leading to Human Systemic Autoimmunity awarded by National Institute of Allergy & Infectious Diseases Key Personnel 2024 - 2029
Molecular Fingerprinting of Lupus in Children awarded by Lupus Research Alliance Key Personnel 2022 - 2026