Cooke, John P.

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TNIK regulation of interferon signaling and endothelial cell response to virus infection. Frontiers in cardiovascular medicine. 2024 Academic Article GET IT
Is Cardiovascular Regeneration Possible?. Methodist DeBakey cardiovascular journal. 2023 Editorial Article GET IT
Transflammation in tissue regeneration and response to injury: How cell-autonomous inflammatory signaling mediates cell plasticity. Advanced drug delivery reviews. 2023 Review GET IT
Premature senescence and cardiovascular disease following cancer treatments: mechanistic insights. Frontiers in cardiovascular medicine. 2023 Review GET IT
Reassessing withholding of statins during Paxlovid therapy: Is it worth risking loss of the pleiotropic effects of statins and cardiovascular protection?. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2023 Academic Article GET IT
Disrupted Stiffness Ratio Alters Nuclear Mechanosensing. Matter. 2023 Academic Article GET IT
Endothelial activation and fibrotic changes are impeded by laminar flow-induced CHK1-SENP2 activity through mechanisms distinct from endothelial-to-mesenchymal cell transition. Frontiers in cardiovascular medicine. 2023 Academic Article GET IT
Telomerase mRNA Enhances Human Skin Engraftment for Wound Healing. Advanced healthcare materials. 2023 Academic Article GET IT
A2AR-mediated lymphangiogenesis via VEGFR2 signaling prevents salt-sensitive hypertension. European heart journal. 2023 Academic Article GET IT
Times cited: 4
An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis. Circulation research. 2023 Academic Article GET IT
Times cited: 4
Possible molecular mechanisms underlying the development of atherosclerosis in cancer survivors. Frontiers in cardiovascular medicine. 2023 Review GET IT
Times cited: 4
Coronary microvascular health in symptomatic patients with prior COVID-19 infection: an updated analysis. European heart journal. Cardiovascular Imaging. 2023 Academic Article GET IT
Publisher Correction: Epigenetic landscape reveals MECOM as an endothelial lineage regulator. 2023 GET IT
Electrically stimulated gene expression under exogenously applied electric fields. Frontiers in molecular biosciences. 2023 Academic Article GET IT
Role of angiogenic transdifferentiation in vascular recovery. Frontiers in cardiovascular medicine. 2023 Review GET IT
Epigenetic landscape reveals MECOM as an endothelial lineage regulator. Nature communications. 2023 Academic Article GET IT
A relay velocity model infers cell-dependent RNA velocity. Nature biotechnology. 2023 Academic Article GET IT
Times cited: 10
Design and rationale of re-energize fontan: Randomized exercise intervention designed to maximize fitness in fontan patients. American heart journal. 2023 Academic Article GET IT
Times cited: 3
Long noncoding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models. The Journal of clinical investigation. 2023 Academic Article GET IT
Times cited: 9
Future Impact of mRNA Therapy on Cardiovascular Diseases. Methodist DeBakey cardiovascular journal. 2022 Review GET IT
Radiation therapy induces immunosenescence mediated by p90RSK. Frontiers in cardiovascular medicine. 2022 Academic Article GET IT
Times cited: 3
MAGI1 inhibits interferon signaling to promote influenza A infection. Frontiers in cardiovascular medicine. 2022 Academic Article GET IT
Coronary Microvascular Health in Patients With Prior COVID-19 Infection. JACC. Cardiovascular imaging. 2022 Letter GET IT
Times cited: 8
Vascular senescence in progeria: role of endothelial dysfunction. European heart journal open. 2022 Academic Article GET IT
Times cited: 8
At the nexus of science, engineering, and medicine: Pasteur's quadrant reconsidered. PNAS nexus. 2022 Academic Article GET IT
Endothelial thioredoxin interacting protein (TXNIP) modulates endothelium-dependent vasorelaxation in hyperglycemia. Microvascular research. 2022 Academic Article GET IT
Times cited: 2
Cardiac Shockwave Therapy - A Novel Therapy for Ischemic Cardiomyopathy?. Frontiers in cardiovascular medicine. 2022 Review GET IT
Times cited: 3
Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications. The journal of cardiovascular aging. 2022 Academic Article GET IT
Times cited: 5
Free Cholesterol Bioavailability and Atherosclerosis. Current atherosclerosis reports. 2022 Review GET IT
Times cited: 7
RBFOX2 is required for establishing RNA regulatory networks essential for heart development. Nucleic acids research. 2022 Academic Article GET IT
Times cited: 18
Acute and Chronic Cardiovascular Manifestations of COVID-19: Role for Endotheliopathy. Methodist DeBakey cardiovascular journal. 2021 Review GET IT
Times cited: 9
Unsupervised Learning for Automated Detection of Coronary Artery Disease Subgroups. Journal of the American Heart Association. 2021 Academic Article GET IT
Times cited: 17
Telomerase therapy reverses vascular senescence and extends lifespan in progeria mice. European heart journal. 2021 Academic Article GET IT
Times cited: 34
Nuclear S-nitrosylation impacts tissue regeneration in zebrafish. Nature communications. 2021 Academic Article GET IT
Times cited: 9
Emerging nanotechnologies in cardiovascular medicine. Nanomedicine : nanotechnology, biology, and medicine. 2021 Editorial Article GET IT
Senescence-Associated Secretory Phenotype as a Hinge Between Cardiovascular Diseases and Cancer. Frontiers in cardiovascular medicine. 2021 Review GET IT
Times cited: 28
Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation. Redox biology. 2021 Academic Article GET IT
Times cited: 17
Induced endothelial cells from peripheral arterial disease patients and neonatal fibroblasts have comparable angiogenic properties. PloS one. 2021 Academic Article GET IT
Times cited: 1
Fli1⁺ cells transcriptional analysis reveals an Lmo2-Prdm16 axis in angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2021 Academic Article GET IT
Times cited: 6
3D Bioprinted Multicellular Vascular Models. Advanced healthcare materials. 2021 Academic Article GET IT
Times cited: 33
New Directions in Therapeutic Angiogenesis and Arteriogenesis in Peripheral Arterial Disease. Circulation research. 2021 Review GET IT
Times cited: 71
Mechanotransduction-on-chip: vessel-chip model of endothelial YAP mechanobiology reveals matrix stiffness impedes shear response. Lab on a chip. 2021 Academic Article GET IT
Times cited: 17
Endothelial Dysfunction-related Neurological Bleeds with Continuous Flow-Left Ventricular Assist Devices Measured by Digital Thermal Monitor. ASAIO journal (American Society for Artificial Internal Organs : 1992). 2021 Academic Article GET IT
Times cited: 1
RNA therapeutics for cardiovascular disease. Current opinion in cardiology. 2021 Review GET IT
Times cited: 11
Biomimetic and immunomodulatory therapeutics as an alternative to natural exosomes for vascular and cardiac applications. Nanomedicine : nanotechnology, biology, and medicine. 2021 Review GET IT
Times cited: 9
The Limitless Future of RNA Therapeutics. Frontiers in bioengineering and biotechnology. 2021 Review GET IT
Times cited: 238
MACMIC Reveals A Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes. Genomics, proteomics & bioinformatics. 2021 Academic Article GET IT
Times cited: 4
mRNA-Enhanced Cell Therapy and Cardiovascular Regeneration. Cells. 2021 Review GET IT
Times cited: 13
Biomimetic nano drug delivery carriers for treating cardiovascular diseases. Nanomedicine : nanotechnology, biology, and medicine. 2021 Review GET IT
Times cited: 13
Role of Endothelial and Mesenchymal Cell Transitions in Heart Failure and Recovery Thereafter. Frontiers in genetics. 2021 Academic Article GET IT
Times cited: 5
On Our Doorstep, A Precious Cargo From MSCs: The Role of Extracellular Vesicles in Stem Cell Therapy. JACC. Basic to translational science. 2020 Editorial Article GET IT
Microengineered Human Vein-Chip Recreates Venous Valve Architecture and Its Contribution to Thrombosis. Small (Weinheim an der Bergstrasse, Germany). 2020 Academic Article GET IT
Times cited: 25
Broad genic repression domains signify enhanced silencing of oncogenes. Nature communications. 2020 Academic Article GET IT
Times cited: 9
Caveats on modeling of nuclear biomechanics. Molecular biology of the cell. 2020 Letter GET IT
Reservoir of Fibroblasts Promotes Recovery From Limb Ischemia. Circulation. 2020 Academic Article GET IT
Times cited: 28
Endotheliopathy of Obesity. Circulation. 2020 Editorial Article GET IT
Times cited: 13
Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson-Gilford Progeria Syndrome. Aging cell. 2020 Academic Article GET IT
Times cited: 39
Machine learning uncovers cell identity regulator by histone code. Nature communications. 2020 Academic Article GET IT
Times cited: 22
Vascular Regeneration in Peripheral Artery Disease. Arteriosclerosis, thrombosis, and vascular biology. 2020 Review GET IT
Times cited: 54
TADsplimer reveals splits and mergers of topologically associating domains for epigenetic regulation of transcription. Genome biology. 2020 Academic Article GET IT
Times cited: 4
aYAP modRNA reduces cardiac inflammation and hypertrophy in a murine ischemia-reperfusion model. Life science alliance. 2019 Academic Article GET IT
Times cited: 22
A Rare Presentation of Paraneoplastic Striatal Encephalitis Associated with Nonsmall Cell Lung Cancer. 2019 GET IT
Times cited: 1
Rapamycin-Loaded Biomimetic Nanoparticles Reverse Vascular Inflammation. Circulation research. 2019 Academic Article GET IT
Times cited: 88
Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. Metabolism: clinical and experimental. 2019 Academic Article GET IT
Times cited: 16
Nuclear S-Nitrosylation Defines an Optimal Zone for Inducing Pluripotency. Circulation. 2019 Academic Article GET IT
Times cited: 16
Dysfunction of iPSC-derived endothelial cells in human Hutchinson-Gilford progeria syndrome. Cell cycle (Georgetown, Tex.). 2019 Academic Article GET IT
Times cited: 15
Asymmetric dimethylarginine predicts impaired epicardial coronary vasomotion in patients with angina in the absence of obstructive coronary artery disease. International journal of cardiology. 2019 Academic Article GET IT
Times cited: 1
Transient introduction of human telomerase mRNA improves hallmarks of progeria cells. Aging cell. 2019 Academic Article GET IT
Times cited: 29
Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein. JCI insight. 2019 Academic Article GET IT
Times cited: 27
Inflammation and Its Role in Regeneration and Repair. Circulation research. 2019 Review GET IT
Times cited: 105
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis. JCI insight. 2019 Academic Article GET IT
Times cited: 32
AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science (New York, N.Y.). 2019 Academic Article GET IT
Times cited: 84
Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure. Circulation research. 2019 Conference Paper GET IT
Times cited: 14
Glycolytic Switch Is Required for Transdifferentiation to Endothelial Lineage. Circulation. 2019 Academic Article GET IT
Times cited: 25
Cardiovascular Risk of Proton Pump Inhibitors. Methodist DeBakey cardiovascular journal. 2019 Review GET IT
Times cited: 19
Dietary Supplements: Facts and Fallacies. Methodist DeBakey cardiovascular journal. 2019 Editorial Article GET IT
Times cited: 2
TBX20 Regulates Angiogenesis Through the Prokineticin 2-Prokineticin Receptor 1 Pathway. Circulation. 2018 Academic Article GET IT
Times cited: 31
Novel Markers for Adverse Events in Atrial Fibrillation. Journal of the American College of Cardiology. 2018 Editorial Article GET IT
Times cited: 1
Induced pluripotent stem cell-derived endothelial cells promote angiogenesis and accelerate wound closure in a murine excisional wound healing model. Bioscience reports. 2018 Academic Article GET IT
Times cited: 51
Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association. Circulation. Genomic and precision medicine. 2018 Review GET IT
Times cited: 18
Arachidonic acid as a target for treating hypertriglyceridemia reproduced by a causal network analysis and an intervention study. Metabolomics : Official journal of the Metabolomic Society. 2018 Letter GET IT
Times cited: 8
Inflammation-targeted vascular nanomedicine. Nature biomedical engineering. 2018 Academic Article GET IT
Times cited: 6
Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming. Antioxidants & redox signaling. 2018 Information Resource GET IT
Times cited: 11
Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. Stem cells (Dayton, Ohio). 2018 Academic Article GET IT
Times cited: 29
Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes. Molecular cancer research : MCR. 2018 Information Resource GET IT
Times cited: 6
Integration of induced pluripotent stem cell-derived endothelial cells with polycaprolactone/gelatin-based electrospun scaffolds for enhanced therapeutic angiogenesis. Stem cell research & therapy. 2018 Academic Article GET IT
Times cited: 45
Biomimetic nanoparticles with enhanced affinity towards activated endothelium as versatile tools for theranostic drug delivery. Theranostics. 2018 Academic Article GET IT
Times cited: 84
Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis. The Journal of biological chemistry. 2017 Academic Article GET IT
Times cited: 6
Transflammation: Innate immune signaling in nuclear reprogramming. Advanced drug delivery reviews. 2017 Information Resource GET IT
Times cited: 12
Telomerase mRNA Reverses Senescence in Progeria Cells. Journal of the American College of Cardiology. 2017 Letter GET IT
Times cited: 10
A Missing LNC in Vascular Diseases. Circulation research. 2017 Editorial Article GET IT
Times cited: 2
Lmo2 (LIM-Domain-Only 2) Modulates Sphk1 (Sphingosine Kinase) and Promotes Endothelial Cell Migration. Arteriosclerosis, thrombosis, and vascular biology. 2017 Academic Article GET IT
Times cited: 20
Peripheral Blood Cytokine Levels After Acute Myocardial Infarction: IL-1β- and IL-6-Related Impairment of Bone Marrow Function. Circulation research. 2017 Academic Article GET IT
Times cited: 33
Retinoic Acid Inducible Gene 1 Protein (RIG1)-Like Receptor Pathway Is Required for Efficient Nuclear Reprogramming. Stem cells (Dayton, Ohio). 2017 Academic Article GET IT
Times cited: 24
AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling. Circulation research. 2017 Academic Article GET IT
Times cited: 39
Discovery of novel determinants of endothelial lineage using chimeric heterokaryons. eLife. 2017 Academic Article GET IT
Times cited: 6
The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity. Investigative ophthalmology & visual science. 2017 Academic Article GET IT
Times cited: 8
A comparison of the pro-angiogenic potential of human induced pluripotent stem cell derived endothelial cells and induced endothelial cells in a murine model of peripheral arterial disease. International journal of cardiology. 2017 Academic Article GET IT
Times cited: 19
Identification of cardiovascular risk factors associated with bone marrow cell subsets in patients with STEMI: a biorepository evaluation from the CCTRN TIME and LateTIME clinical trials. Basic research in cardiology. 2016 Academic Article GET IT
Times cited: 15
The senescence accelerated mouse prone 8 (SAMP8): A novel murine model for cardiac aging. Ageing research reviews. 2016 Information Resource GET IT
Times cited: 19
LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration. Journal of the American Heart Association. 2016 Academic Article GET IT
Times cited: 17
Dynamic measures of skeletal muscle dialysate and plasma amino acid concentration in response to exercise and nutrient ingestion in healthy adult males. Amino acids. 2016 Academic Article GET IT
Times cited: 5
Angina and Future Cardiovascular Events in Stable Patients With Coronary Artery Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry. Journal of the American Heart Association. 2016 Academic Article GET IT
Times cited: 48
Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation. Circulation research. 2016 Academic Article GET IT
Times cited: 27
Enhancing Stent Effectiveness with Nanofeatures. Methodist DeBakey cardiovascular journal. 2016 Review GET IT
Times cited: 14
Nanotherapeutic Solutions for Cardiovascular Disease. Methodist DeBakey cardiovascular journal. 2016 Editorial Article GET IT
Times cited: 5
Vascular Inflammation: A Novel Access Route for Nanomedicine. Methodist DeBakey cardiovascular journal. 2016 Review GET IT
Times cited: 24
Erratum: Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA. 2016 GET IT
Bone marrow cell characteristics associated with patient profile and cardiac performance outcomes in the LateTIME-Cardiovascular Cell Therapy Research Network (CCTRN) trial. American heart journal. 2016 Academic Article GET IT
Times cited: 16
Aligned nanofibrillar collagen scaffolds - Guiding lymphangiogenesis for treatment of acquired lymphedema. Biomaterials. 2016 Academic Article GET IT
Times cited: 54
The use of machine learning for the identification of peripheral artery disease and future mortality risk. Journal of vascular surgery. 2016 Academic Article GET IT
Times cited: 94
Polymer-DNA Nanoparticle-Induced CXCR4 Overexpression Improves Stem Cell Engraftment and Tissue Regeneration in a Mouse Hindlimb Ischemia Model. Theranostics. 2016 Academic Article GET IT
Times cited: 20
Proton Pump Inhibitors Accelerate Endothelial Senescence. Circulation research. 2016 Academic Article GET IT
Times cited: 109
Optimal ROS Signaling Is Critical for Nuclear Reprogramming. Cell reports. 2016 Academic Article GET IT
Times cited: 98
Therapeutic transdifferentiation of human fibroblasts into endothelial cells using forced expression of lineage-specific transcription factors. Journal of tissue engineering. 2016 Academic Article GET IT
Times cited: 28
Erratum: Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA. 2016 GET IT
Targeted delivery of human iPS-ECs overexpressing IL-8 receptors inhibits neointimal and inflammatory responses to vascular injury in the rat. American journal of physiology. Heart and circulatory physiology. 2016 Academic Article GET IT
Times cited: 13
Reply. Gastroenterology. 2015 Article GET IT
Times cited: 1
Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA. Cell discovery. 2015 Academic Article GET IT
Times cited: 44
Identification of Bone Marrow Cell Subpopulations Associated With Improved Functional Outcomes in Patients With Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial. Cell transplantation. 2015 Academic Article GET IT
Times cited: 29
Response to Letter Regarding Article "Transdifferentiation of Human Fibroblasts to Endothelial Cells: Role of Innate Immunity". Circulation. 2015 Article GET IT
Times cited: 1
Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis. Journal of translational medicine. 2015 Academic Article GET IT
Times cited: 98
Lansoprazole worsens asthma control in poor metabolizers: is nitric oxide involved?. Annals of the American Thoracic Society. 2015 Article GET IT
Times cited: 1
Aligned-Braided Nanofibrillar Scaffold with Endothelial Cells Enhances Arteriogenesis. ACS nano. 2015 Academic Article GET IT
Times cited: 57
Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population. PloS one. 2015 Academic Article GET IT
Times cited: 257
The Society for Vascular Medicine: the first quarter century. Vascular medicine (London, England). 2015 Academic Article GET IT
Times cited: 4
Effect of physical activity assessment on prognostication for peripheral artery disease and mortality. Mayo Clinic proceedings. 2015 Academic Article GET IT
Times cited: 18
Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2015 Academic Article GET IT
Times cited: 68
Guest Editor John Cooke Lends Expertise on Special Cardiovascular Regeneration Issue. Methodist DeBakey cardiovascular journal. 2015 Article GET IT
Mechanisms of Atherosclerosis: New Insights and Novel Therapeutic Approaches. Methodist DeBakey cardiovascular journal. 2015 Article GET IT
Times cited: 6
New Insights Into Tobacco-Induced Vascular Disease: Clinical Ramifications. Methodist DeBakey cardiovascular journal. 2015 Review GET IT
Times cited: 5
Telomerase Therapy to Reverse Cardiovascular Senescence. Methodist DeBakey cardiovascular journal. 2015 Review GET IT
Times cited: 19
Therapeutic Transdifferentiation: A Novel Approach for Ischemic Syndromes. Methodist DeBakey cardiovascular journal. 2015 Review GET IT
Times cited: 2
Bone marrow characteristics associated with changes in infarct size after STEMI: a biorepository evaluation from the CCTRN TIME trial. Circulation research. 2014 Academic Article GET IT
Times cited: 39
Fatal herpes simplex virus hepatitis following neoadjuvant chemoradiotherapy and anterior resection for rectal cancer. 2014 GET IT
Times cited: 3
Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity. Circulation. 2014 Academic Article GET IT
Times cited: 126
Innate immunity and epigenetic plasticity in cellular reprogramming. Current opinion in genetics & development. 2014 Information Resource GET IT
Times cited: 10
Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes. Circulation research. 2014 Academic Article GET IT
Times cited: 62
Rationale and design for PACE: patients with intermittent claudication injected with ALDH bright cells. American heart journal. 2014 Academic Article GET IT
Times cited: 23
Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators. Nature communications. 2014 Academic Article GET IT
Times cited: 134
β2-microglobulin, cystatin C, and creatinine and risk of symptomatic peripheral artery disease. Journal of the American Heart Association. 2014 Academic Article GET IT
Times cited: 23
Clinical and socioeconomic factors associated with unrecognized peripheral artery disease. Vascular medicine (London, England). 2014 Academic Article GET IT
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease. Atherosclerosis. 2014 Academic Article GET IT
Times cited: 47
Near-infrared II fluorescence for imaging hindlimb vessel regeneration with dynamic tissue perfusion measurement. Circulation. Cardiovascular imaging. 2014 Academic Article GET IT
Times cited: 84
Self-reported history of childhood smoking is associated with an increased risk for peripheral arterial disease independent of lifetime smoking burden. PloS one. 2014 Academic Article GET IT
Times cited: 5
Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 87
Microvascular endothelial cells migrate upstream and align against the shear stress field created by impinging flow. Biophysical journal. 2014 Academic Article GET IT
Times cited: 90
Characterization of a fluorescent probe for imaging nitric oxide. Journal of vascular research. 2013 Academic Article GET IT
Times cited: 8
The combination of 9p21.3 genotype and biomarker profile improves a peripheral artery disease risk prediction model. Vascular medicine (London, England). 2013 Academic Article GET IT
Times cited: 6
Concurrent generation of functional smooth muscle and endothelial cells via a vascular progenitor. Stem cells translational medicine. 2013 Academic Article GET IT
Times cited: 41
A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis. Diabetes. 2013 Academic Article GET IT
Times cited: 55
Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature. Circulation. 2013 Academic Article GET IT
Times cited: 70
A novel and potent inhibitor of dimethylarginine dimethylaminohydrolase: a modulator of cardiovascular nitric oxide. The Journal of pharmacology and experimental therapeutics. 2013 Academic Article GET IT
Times cited: 29
Clinical trials of adult stem cell therapy for peripheral artery disease. Methodist DeBakey cardiovascular journal. 2013 Information Resource GET IT
Times cited: 27
Induced pluripotent stem cells: how they will change the practice of cardiovascular medicine. Methodist DeBakey cardiovascular journal. 2013 Information Resource GET IT
Times cited: 9
Therapeutic transdifferentiation: can we generate cardiac tissue rather than scar after myocardial injury?. Methodist DeBakey cardiovascular journal. 2013 Information Resource GET IT
Times cited: 5
Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia. American journal of respiratory cell and molecular biology. 2013 Academic Article GET IT
Times cited: 15
Chemotaxis of human induced pluripotent stem cell-derived endothelial cells. American journal of translational research. 2013 Academic Article GET IT
Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Circulation. 2013 Academic Article GET IT
Times cited: 198
Alternative ankle-brachial index method identifies additional at-risk individuals. Journal of the American College of Cardiology. 2013 Academic Article GET IT
Times cited: 44
Walking impairment questionnaire improves mortality risk prediction models in a high-risk cohort independent of peripheral arterial disease status. Circulation. Cardiovascular quality and outcomes. 2013 Academic Article GET IT
Times cited: 16
FXR agonist INT-747 upregulates DDAH expression and enhances insulin sensitivity in high-salt fed Dahl rats. PloS one. 2013 Academic Article GET IT
Times cited: 25
Conversion of human fibroblasts to functional endothelial cells by defined factors. Arteriosclerosis, thrombosis, and vascular biology. 2013 Academic Article GET IT
Times cited: 102
Pharmacovigilance using Clinical Text. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science. 2013 Academic Article GET IT
The modulation of endothelial cell morphology, function, and survival using anisotropic nanofibrillar collagen scaffolds. Biomaterials. 2013 Academic Article GET IT
Times cited: 79
Therapeutic transdifferentiation: a novel approach for vascular disease. Circulation research. 2013 Article GET IT
Times cited: 16
Spatial patterning of endothelium modulates cell morphology, adhesiveness and transcriptional signature. Biomaterials. 2013 Academic Article GET IT
Times cited: 57
Human induced pluripotent stem cell-derived endothelial cells exhibit functional heterogeneity. American journal of translational research. 2013 Academic Article GET IT
Guest editors Paolo Decuzzi & John P. Cooke lend expertise on special regenerative medicine issue. Methodist DeBakey cardiovascular journal. 2013 Editorial Article GET IT
Times cited: 1
Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem cells (Dayton, Ohio). 2013 Academic Article GET IT
Times cited: 96
The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis. The Journal of pathology. 2013 Information Resource GET IT
Times cited: 30
Usefulness of the addition of beta-2-microglobulin, cystatin C and C-reactive protein to an established risk factors model to improve mortality risk prediction in patients undergoing coronary angiography. The American journal of cardiology. 2013 Academic Article GET IT
Times cited: 20
Multifunctional in vivo vascular imaging using near-infrared II fluorescence. Nature medicine. 2012 Academic Article GET IT
Times cited: 794
Activation of innate immunity is required for efficient nuclear reprogramming. Cell. 2012 Academic Article GET IT
Times cited: 274
Endothelial cells derived from nuclear reprogramming. Circulation research. 2012 Information Resource GET IT
Times cited: 39
A validated biomarker panel to identify peripheral artery disease. Vascular medicine (London, England). 2012 Academic Article GET IT
Times cited: 10
Exercise capacity is the strongest predictor of mortality in patients with peripheral arterial disease. Journal of vascular surgery. 2012 Academic Article GET IT
Times cited: 81
Aligned nanofibrillar collagen regulates endothelial organization and migration. Regenerative medicine. 2012 Academic Article GET IT
Times cited: 53
PPARδ activation protects endothelial function in diabetic mice. Diabetes. 2012 Academic Article GET IT
Times cited: 58
Imaging vascular nicotine receptors: a new window onto vascular disease. JACC. Cardiovascular imaging. 2012 Editorial Article GET IT
Times cited: 3
Endovascular correction of cerebrovenous anomalies in multiple sclerosis: a retrospective review of an uncontrolled case series. Vascular medicine (London, England). 2012 Academic Article GET IT
Times cited: 8
Development of a dimethylarginine dimethylaminohydrolase (DDAH) assay for high-throughput chemical screening. Journal of biomolecular screening. 2012 Academic Article GET IT
Times cited: 21
Development of pluripotent stem cells for vascular therapy. Vascular pharmacology. 2012 Information Resource GET IT
Times cited: 33
In Memoriam of John T. Shepherd, MD, DSc. Circulation. 2012 Academic Article GET IT
Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats. Antioxidants & redox signaling. 2011 Academic Article GET IT
Times cited: 70
Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arteriosclerosis, thrombosis, and vascular biology. 2011 Academic Article GET IT
Times cited: 235
Meal-induced increases in C-reactive protein, interleukin-6 and tumour necrosis factor α are attenuated by prandial + basal insulin in patients with Type 2 diabetes. Diabetic medicine : a journal of the British Diabetic Association. 2011 Academic Article GET IT
Times cited: 18
Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance. Cardiovascular diabetology. 2011 Academic Article GET IT
Times cited: 38
Solubility partner IF2 Domain I enables high yield synthesis of transducible transcription factors in Escherichia coli. Protein expression and purification. 2011 Academic Article GET IT
Times cited: 9
DDAH says NO to ADMA. Arteriosclerosis, thrombosis, and vascular biology. 2011 Editorial Article GET IT
Times cited: 46
Low lifetime recreational activity is a risk factor for peripheral arterial disease. Journal of vascular surgery. 2011 Academic Article GET IT
Times cited: 36
Identification and classification of acute cardiac rejection by intragraft transcriptional profiling. Circulation. 2011 Academic Article GET IT
Times cited: 27
Dietary nitrate, nitric oxide, and restenosis. The Journal of clinical investigation. 2011 Article GET IT
Times cited: 16
The role of nicotine in the pathogenesis of atherosclerosis. Atherosclerosis. 2011 Article GET IT
Times cited: 84
Sex differences in the prevalence of peripheral artery disease in patients undergoing coronary catheterization. Vascular medicine (London, England). 2010 Academic Article GET IT
Times cited: 19
Assessing endothelial vasodilator function with the Endo-PAT 2000. Journal of visualized experiments : JoVE. 2010 Academic Article GET IT
Times cited: 124
Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease?. Vascular medicine (London, England). 2010 Academic Article GET IT
Times cited: 22
Role of nitric oxide signaling in endothelial differentiation of embryonic stem cells. Stem cells and development. 2010 Academic Article GET IT
Times cited: 36
Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells. Circulation. 2010 Information Resource GET IT
Times cited: 162
A matrix micropatterning platform for cell localization and stem cell fate determination. Acta biomaterialia. 2010 Academic Article GET IT
Times cited: 48
Relationship of asymmetric dimethylarginine and homocysteine to vascular aging in systemic lupus erythematosus patients. Arthritis and rheumatism. 2010 Academic Article GET IT
Times cited: 30
Asymmetric dimethylarginine correlates with measures of disease severity, major adverse cardiovascular events and all-cause mortality in patients with peripheral arterial disease. Vascular medicine (London, England). 2010 Academic Article GET IT
Times cited: 51
Biomarkers of peripheral arterial disease. Journal of the American College of Cardiology. 2010 Information Resource GET IT
Times cited: 81
DDAH: a target for vascular therapy?. Vascular medicine (London, England). 2010 Editorial Article GET IT
Times cited: 15
Topical mecamylamine for diabetic macular edema. American journal of ophthalmology. 2010 Academic Article GET IT
Times cited: 24
Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion. Arteriosclerosis, thrombosis, and vascular biology. 2010 Academic Article GET IT
Times cited: 122
Cerebral autoregulation in the vertebral and middle cerebral arteries during combine head upright tilt and lower body negative pressure in healthy humans. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2010 Academic Article GET IT
Times cited: 22
Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. Circulation research. 2009 Academic Article GET IT
Times cited: 37
Cholinergic modulation of angiogenesis: role of the 7 nicotinic acetylcholine receptor. Journal of cellular biochemistry. 2009 Academic Article GET IT
Times cited: 56
Chronic exposure to nicotine impairs cholinergic angiogenesis. Vascular medicine (London, England). 2009 Academic Article GET IT
Times cited: 45
nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis. PloS one. 2009 Academic Article GET IT
Times cited: 57
Hypercholesterolemia impairs exercise capacity in mice. Vascular medicine (London, England). 2009 Academic Article GET IT
Times cited: 13
Does improving mood in depressed patients alter factors that may affect cardiovascular disease risk?. Journal of psychiatric research. 2009 Academic Article GET IT
Times cited: 39
What is the optimal duration of tilt testing for the assessment of patients with suspected postural tachycardia syndrome?. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2009 Academic Article GET IT
Times cited: 10
Embryonic stem cell-derived endothelial cells for treatment of hindlimb ischemia. Journal of visualized experiments : JoVE. 2009 Academic Article GET IT
Times cited: 15
Murine model of hindlimb ischemia. Journal of visualized experiments : JoVE. 2009 Academic Article GET IT
Times cited: 187
Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. The Journal of cell biology. 2009 Academic Article GET IT
Times cited: 164
A review of postural orthostatic tachycardia syndrome. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2009 Review GET IT
Times cited: 57
Endothelial nicotinic acetylcholine receptors and angiogenesis. Trends in cardiovascular medicine. 2008 Information Resource GET IT
Times cited: 82
Letter by Stuehlinger et al regarding article, "Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction". Circulation. 2008 Article GET IT
A biomarker panel for peripheral arterial disease. Vascular medicine (London, England). 2008 Academic Article GET IT
Times cited: 50
Critical determinants of limb ischemia. Journal of the American College of Cardiology. 2008 Editorial Article GET IT
Times cited: 2
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia. American journal of physiology. Heart and circulatory physiology. 2008 Academic Article GET IT
Times cited: 57
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. Investigative ophthalmology & visual science. 2008 Academic Article GET IT
Times cited: 55
Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus. Transplantation. 2008 Academic Article GET IT
Times cited: 21
Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity. Arteriosclerosis, thrombosis, and vascular biology. 2008 Academic Article GET IT
Times cited: 87
Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation. Stroke. 2007 Academic Article GET IT
Times cited: 64
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation. 2007 Academic Article GET IT
Times cited: 203
Beta2-microglobulin as a biomarker in peripheral arterial disease: proteomic profiling and clinical studies. Circulation. 2007 Academic Article GET IT
Times cited: 133
L-arginine supplementation in peripheral arterial disease: no benefit and possible harm. Circulation. 2007 Academic Article GET IT
Times cited: 151
A novel bioluminescent tumor model of human renal cancer cell lines: an in vitro and in vivo characterization. The Journal of urology. 2007 Academic Article GET IT
Times cited: 9
Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury. Cardiovascular research. 2007 Academic Article GET IT
Times cited: 47
Frequent occult infection with Cytomegalovirus in cardiac transplant recipients despite antiviral prophylaxis. Journal of clinical microbiology. 2007 Academic Article GET IT
Times cited: 25
Asymmetric dimethyl-arginine and coronary artery calcification in young adults entering middle age: the CARDIA Study. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. 2007 Academic Article GET IT
Times cited: 27
Changes in coronary arterial dimensions early after cardiac transplantation. Transplantation. 2007 Academic Article GET IT
Times cited: 41
NOx and ADMA changes with focal ischemia, amelioration with the chaperonin GroEL. Neuroscience letters. 2007 Academic Article GET IT
Times cited: 12
Dimethylarginine dimethylaminohydrolase promotes endothelial repair after vascular injury. Journal of the American College of Cardiology. 2007 Academic Article GET IT
Times cited: 65
Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia. Circulation research. 2007 Academic Article GET IT
Times cited: 198
Should we measure asymmetric dimethylarginine in patients with coronary artery disease?. Clinical chemistry. 2007 Editorial Article GET IT
Times cited: 8
[Coronary allograft vasculopathy: pathophysiological interaction between the immune system, infections and metabolic syndrome]. Giornale italiano di cardiologia (2006). 2007 Information Resource GET IT
Times cited: 3
A pilot study of ranolazine in patients with intermittent claudication. International angiology : a journal of the International Union of Angiology. 2006 Academic Article GET IT
Times cited: 8
Endothelial progenitor cells participate in nicotine-mediated angiogenesis. Journal of the American College of Cardiology. 2006 Academic Article GET IT
Times cited: 90
Microenvironmental VEGF distribution is critical for stable and functional vessel growth in ischemia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2006 Academic Article GET IT
Times cited: 101
A central role for nicotinic cholinergic regulation of growth factor-induced endothelial cell migration. Arteriosclerosis, thrombosis, and vascular biology. 2006 Academic Article GET IT
Times cited: 75
Limb hemodynamics are not predictive of functional capacity in patients with PAD. Vascular medicine (London, England). 2006 Academic Article GET IT
Times cited: 59
T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease. Circulation. 2006 Academic Article GET IT
Times cited: 77
Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. Transplantation. 2006 Academic Article GET IT
Times cited: 124
Letter by Kielstein et al regarding article, "Renal function as a predictor of outcome in a broad spectrum of patients with heart failure". Circulation. 2006 Article GET IT
Psychophysiological and cortisol responses to psychological stress in depressed and nondepressed older men and women with elevated cardiovascular disease risk. Psychosomatic medicine. 2006 Academic Article GET IT
Times cited: 70
ADMA increases arterial stiffness and decreases cerebral blood flow in humans. Stroke. 2006 Academic Article GET IT
Times cited: 177
Re: The American "board" of vascular medicine: questions and concerns. Journal of vascular and interventional radiology : JVIR. 2006 Letter GET IT
Abnormal cardiovascular response to exercise in patients with peripheral arterial disease: Implications for management. Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing. 2005 Academic Article GET IT
Times cited: 10
A pilot study of L-arginine supplementation on functional capacity in peripheral arterial disease. Vascular medicine (London, England). 2005 Academic Article GET IT
Times cited: 34
Mechanisms of Raynaud's disease. Vascular medicine (London, England). 2005 Information Resource GET IT
Times cited: 106
Vascular compliance versus flow-mediated vasodilation: correlation with cardiovascular risk factors. Vascular medicine (London, England). 2005 Academic Article GET IT
Times cited: 13
Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease. Circulation. 2005 Academic Article GET IT
Times cited: 78
Homocysteine-induced vascular dysregulation is mediated by the NMDA receptor. Vascular medicine (London, England). 2005 Academic Article GET IT
Times cited: 37
ADMA: an emerging cardiovascular risk factor. Vascular medicine (London, England). 2005 Editorial Article GET IT
Times cited: 30
Insulin resistance: potential role of the endogenous nitric oxide synthase inhibitor ADMA. Vascular medicine (London, England). 2005 Information Resource GET IT
Times cited: 89
Suboptimal intensity of risk factor modification in PAD. Vascular medicine (London, England). 2005 Academic Article GET IT
Times cited: 23
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Circulation. 2005 Academic Article GET IT
Times cited: 136
ADMA regulates angiogenesis: genetic and metabolic evidence. Vascular medicine (London, England). 2005 Academic Article GET IT
Times cited: 24
Lymphatic biology and the microcirculation: past, present and future. Microcirculation (New York, N.Y. : 1994). 2005 Information Resource GET IT
Times cited: 61
Capillary electrophoretic and micellar electrokinetic separations of asymmetric dimethyl-L-arginine and structurally related amino acids: quantitation in human plasma. Journal of separation science. 2004 Academic Article GET IT
Times cited: 31
Exercise patterns and cardiovascular fitness of patients with peripheral arterial disease. Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing. 2004 Academic Article GET IT
Times cited: 10
Adenoviral gene transfer with soluble vascular endothelial growth factor receptors impairs angiogenesis and perfusion in a murine model of hindlimb ischemia. Circulation. 2004 Academic Article GET IT
Times cited: 72
The pivotal role of nitric oxide for vascular health. The Canadian journal of cardiology. 2004 Information Resource GET IT
Times cited: 58
Asymmetrical dimethylarginine: the Uber marker?. Circulation. 2004 Information Resource GET IT
Times cited: 355
Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia. Circulation. 2004 Academic Article GET IT
Times cited: 57
Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis. Gene therapy. 2004 Academic Article GET IT
Times cited: 42
Isoflavones improve vascular reactivity in post-menopausal women with hypercholesterolemia. Vascular medicine (London, England). 2004 Academic Article GET IT
Times cited: 51
Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy. Vascular medicine (London, England). 2004 Academic Article GET IT
Times cited: 17
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis. Circulation. 2004 Academic Article GET IT
Times cited: 125
Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay. Clinical chemistry and laboratory medicine. 2004 Academic Article GET IT
Times cited: 215
Nicotine and angiogenesis: a new paradigm for tobacco-related diseases. Annals of medicine. 2004 Information Resource GET IT
Times cited: 98
Predictors of physical function in patients with peripherial arterial disease and claudication. Progress in cardiovascular nursing. 2004 Academic Article GET IT
Times cited: 6
Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase. Atherosclerosis. Supplements. 2003 Academic Article GET IT
Times cited: 89
Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Circulation. 2003 Academic Article GET IT
Times cited: 283
Second hand smoke stimulates tumor angiogenesis and growth. Cancer cell. 2003 Academic Article GET IT
Times cited: 111
Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial. Circulation. 2003 Academic Article GET IT
Times cited: 213
Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine. Circulation. 2003 Academic Article GET IT
Times cited: 283
Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women. Journal of hypertension. 2003 Academic Article GET IT
Times cited: 64
A peculiar result and a fanciful hypothesis regarding L-arginine. Arteriosclerosis, thrombosis, and vascular biology. 2003 Article GET IT
Times cited: 4
Flow-responsive remodeling after angioplasty is enhanced by high cholesterol diet. Prevention with pyrrolidine dithiocarbamate. Atherosclerosis. 2003 Academic Article GET IT
Times cited: 5
Gender differences in perception of PAD: a pilot study. Vascular medicine (London, England). 2003 Academic Article GET IT
Times cited: 32
Cardiac allograft vasculopathy and dysregulation of the NO synthase pathway. Arteriosclerosis, thrombosis, and vascular biology. 2003 Information Resource GET IT
Times cited: 65
NOS inhibition accelerates atherogenesis: reversal by exercise. American journal of physiology. Heart and circulatory physiology. 2003 Academic Article GET IT
Times cited: 46
Nicotine promotes arteriogenesis. Journal of the American College of Cardiology. 2003 Academic Article GET IT
Times cited: 109
Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions. Circulation. 2003 Academic Article GET IT
Times cited: 182
Flow, NO, and atherogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2003 Article GET IT
Times cited: 122
Short polymers of arginine rapidly translocate into vascular cells: effects on nitric oxide synthesis. Circulation journal : official journal of the Japanese Circulation Society. 2002 Academic Article GET IT
Times cited: 12
Endothelial determinants of dendritic cell adhesion and migration: new implications for vascular diseases. Arteriosclerosis, thrombosis, and vascular biology. 2002 Academic Article GET IT
Times cited: 97
Homocysteine impairs coronary microvascular dilator function in humans. Journal of the American College of Cardiology. 2002 Academic Article GET IT
Times cited: 81
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation. 2002 Academic Article GET IT
Times cited: 604
A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors. The Journal of clinical investigation. 2002 Academic Article GET IT
Times cited: 314
Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes. Metabolism: clinical and experimental. 2002 Academic Article GET IT
Times cited: 133
Nicotine accelerates angiogenesis and wound healing in genetically diabetic mice. The American journal of pathology. 2002 Academic Article GET IT
Times cited: 149
Nitric oxide and angiogenesis. Circulation. 2002 Editorial Article GET IT
Times cited: 210
Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA. 2002 Academic Article GET IT
Times cited: 534
Effect of local delivery of L-arginine on in-stent restenosis in humans. The American journal of cardiology. 2002 Academic Article GET IT
Times cited: 34
Statins have biphasic effects on angiogenesis. Circulation. 2002 Academic Article GET IT
Times cited: 566
Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation. 2001 Academic Article GET IT
Times cited: 584
Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus. The American journal of cardiology. 2001 Academic Article GET IT
Times cited: 310
Proteinuria in a placebo-controlled study of basic fibroblast growth factor for intermittent claudication. Vascular medicine (London, England). 2001 Academic Article GET IT
Times cited: 41
eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization. Circulation research. 2001 Academic Article GET IT
Times cited: 215
Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF. Cardiovascular research. 2001 Academic Article GET IT
Times cited: 138
Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine. Journal of the American College of Cardiology. 2001 Academic Article GET IT
Times cited: 212
Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis. Nature medicine. 2001 Academic Article GET IT
Times cited: 630
Go with the flow. Circulation. 2001 Editorial Article GET IT
Times cited: 19
Propionyl-L-carnitine improves exercise performance and functional status in patients with claudication. The American journal of medicine. 2001 Academic Article GET IT
Times cited: 100
Atherogenesis and the arginine hypothesis. Current atherosclerosis reports. 2001 Information Resource GET IT
Times cited: 51
L-arginine enhances aerobic exercise capacity in association with augmented nitric oxide production. Journal of applied physiology (Bethesda, Md. : 1985). 2001 Academic Article GET IT
Times cited: 58
Cholesterol-induced upregulation of angiotensin II and its effects on monocyte-endothelial interaction and superoxide production. Vascular medicine (London, England). 2001 Academic Article GET IT
Times cited: 7
Effects of stenting on adjacent vascular distensibility and neointima formation: role of nitric oxide. Vascular medicine (London, England). 2001 Academic Article GET IT
Times cited: 7
Maintaining the endothelium: preventive strategies for vessel integrity. Preventive cardiology. 2001 Academic Article GET IT
An endogenous inhibitor of nitric oxide synthase regulates endothelial adhesiveness for monocytes. Journal of the American College of Cardiology. 2000 Academic Article GET IT
Times cited: 217
Rapid and efficient vascular transport of arginine polymers inhibits myointimal hyperplasia. Circulation. 2000 Academic Article GET IT
Times cited: 17
Photoangioplasty for human peripheral atherosclerosis: results of a phase I trial of photodynamic therapy with motexafin lutetium (Antrin). Circulation. 2000 Academic Article GET IT
Times cited: 78
Executive Summary: Pivotal Research in Cardiovascular Syndromes in the Elderly. The American journal of geriatric cardiology. 2000 Academic Article GET IT
Angiogenesis is impaired by hypercholesterolemia: role of asymmetric dimethylarginine. Circulation. 2000 Academic Article GET IT
Times cited: 117
Decongestive lymphatic therapy for patients with cancer-related or primary lymphedema. The American journal of medicine. 2000 Academic Article GET IT
Times cited: 128
Does ADMA cause endothelial dysfunction?. Arteriosclerosis, thrombosis, and vascular biology. 2000 Information Resource GET IT
Times cited: 523
Endothelial dysfunction in hypercholesterolemia is reversed by a nutritional product designed to enhance nitric oxide activity. Cardiovascular drugs and therapy. 2000 Academic Article GET IT
Times cited: 50
Phytoestrogens and cardiovascular health. Journal of the American College of Cardiology. 2000 Information Resource GET IT
Times cited: 253
Asymmetric dimethylarginine increases mononuclear cell adhesiveness in hypercholesterolemic humans. Arteriosclerosis, thrombosis, and vascular biology. 2000 Academic Article GET IT
Times cited: 128
Nitric oxide induces the synthesis of vascular endothelial growth factor by rat vascular smooth muscle cells. Arteriosclerosis, thrombosis, and vascular biology. 2000 Academic Article GET IT
Times cited: 277
Differential expression of nitric oxide by dermal microvascular endothelial cells from patients with scleroderma. Vascular medicine (London, England). 2000 Academic Article GET IT
Times cited: 56
Maintaining the endothelium: preventive strategies for vessel integrity. Preventive cardiology. 2000 Academic Article GET IT
Nutritional therapy for peripheral arterial disease: a double-blind, placebo-controlled, randomized trial of HeartBar. Vascular medicine (London, England). 2000 Academic Article GET IT
Times cited: 95
Vascular endothelial growth factor is efficiently synthesized in spite of low transfection efficiency of pSG5VEGF plasmids in vascular smooth muscle cells. Vascular medicine (London, England). 2000 Academic Article GET IT
Times cited: 17
Local L-arginine delivery after balloon angioplasty reduces monocyte binding and induces apoptosis. Circulation. 1999 Academic Article GET IT
Times cited: 37
Gene transfer of nitric oxide synthase: effects on endothelial biology. Journal of the American College of Cardiology. 1999 Academic Article GET IT
Times cited: 43
Mononuclear cell adherence to cultured endothelium is enhanced by hypertension and insulin resistance in healthy nondiabetic volunteers. Circulation. 1999 Academic Article GET IT
Times cited: 43
Effects of L-arginine on atherogenesis and endothelial dysfunction due to secondhand smoke. Hypertension (Dallas, Tex. : 1979). 1999 Academic Article GET IT
Times cited: 35
The role of nitric oxide in atherosclerosis. Coronary artery disease. 1999 Information Resource GET IT
Times cited: 28
Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase. Circulation. 1999 Academic Article GET IT
Times cited: 607
Impaired aerobic capacity in hypercholesterolemic mice: partial reversal by exercise training. The American journal of physiology. 1999 Academic Article GET IT
Times cited: 81
Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis. Circulation. 1999 Academic Article GET IT
Times cited: 703
Regression of atherosclerosis: role of nitric oxide and apoptosis. Circulation. 1999 Academic Article GET IT
Times cited: 127
[Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis]. Journal of cardiology. 1999 Academic Article GET IT
Times cited: 16
L-arginine and nitric oxide-related compounds in plasma: comparison of normal and arginine-free diets in a 24-h crossover study. Vascular medicine (London, England). 1999 Academic Article GET IT
Times cited: 25
The 1998 Nobel prize in Medicine: clinical implications for 1999 and beyond. Vascular medicine (London, England). 1999 Editorial Article GET IT
Times cited: 2
Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation. 1998 Academic Article GET IT
Times cited: 1061
Modulation of the nitric oxide synthase pathway in atherosclerosis. Experimental physiology. 1998 Information Resource GET IT
Times cited: 26
Limb blood flow during exercise is dependent on nitric oxide. Circulation. 1998 Academic Article GET IT
Times cited: 112
Interaction of diabetes and hypertension on determinants of endothelial adhesiveness. Arteriosclerosis, thrombosis, and vascular biology. 1998 Academic Article GET IT
Times cited: 54
Cardiovascular effects of L-arginine. Current opinion in nephrology and hypertension. 1998 Information Resource GET IT
Times cited: 63
Peripheral arterial insufficiency: mechanisms, natural history, and therapeutic options. Advances in internal medicine. 1998 Information Resource GET IT
Times cited: 26
Adhesiveness of mononuclear cells in hypercholesterolemic humans is normalized by dietary L-arginine. Arteriosclerosis, thrombosis, and vascular biology. 1997 Academic Article GET IT
Times cited: 67
Anti-CD43 inhibits monocyte-endothelial adhesion in inflammation and atherogenesis. Blood. 1997 Academic Article GET IT
Times cited: 39
Therapeutic interventions in endothelial dysfunction: endothelium as a target organ. Clinical cardiology. 1997 Information Resource GET IT
Times cited: 29
Adherence of mononuclear cells to endothelium in vitro is increased in patients with NIDDM. Diabetes care. 1997 Academic Article GET IT
Times cited: 45
Nitric oxide regulates monocyte chemotactic protein-1. Circulation. 1997 Academic Article GET IT
Times cited: 188
Derangements of the nitric oxide synthase pathway, L-arginine, and cardiovascular diseases. Circulation. 1997 Editorial Article GET IT
Times cited: 123
Novel vascular molecule involved in monocyte adhesion to aortic endothelium in models of atherogenesis. The Journal of experimental medicine. 1997 Academic Article GET IT
Times cited: 32
Local intramural delivery of L-arginine enhances nitric oxide generation and inhibits lesion formation after balloon angioplasty. Circulation. 1997 Academic Article GET IT
Times cited: 107
Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts. The Journal of clinical investigation. 1997 Academic Article GET IT
Times cited: 106
Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans. Journal of the American College of Cardiology. 1997 Academic Article GET IT
Times cited: 155
Arginine: a new therapy for atherosclerosis?. Circulation. 1997 Editorial Article GET IT
Times cited: 78
Nitric oxide synthase: role in the genesis of vascular disease. Annual review of medicine. 1997 Information Resource GET IT
Times cited: 634
Role of digital artery adrenoceptors in Raynaud's disease. Vascular medicine (London, England). 1997 Academic Article GET IT
Times cited: 27
Cardiovascular effects of exercise: role of endothelial shear stress. Journal of the American College of Cardiology. 1996 Academic Article GET IT
Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits. Journal of the American College of Cardiology. 1996 Academic Article GET IT
Times cited: 69
Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1. Circulation. 1996 Academic Article GET IT
Times cited: 254
News from the Society for Vascular Medicine and Biology. Vascular medicine (London, England). 1996 Academic Article GET IT
Role of nitric oxide in progression and regression of atherosclerosis. The Western journal of medicine. 1996 Information Resource GET IT
Times cited: 36
Hypertension-enhanced monocyte adhesion in experimental atherosclerosis. Journal of vascular surgery. 1996 Academic Article GET IT
Times cited: 37
Expression of inducible nitric oxide synthase in human heart failure. Circulation. 1996 Academic Article GET IT
Times cited: 431
Exercise rehabilitation for treatment of claudication. JAMA. 1996 Article GET IT
Times cited: 3
Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle. Circulation. 1996 Academic Article GET IT
Concern about safety of carotid angioplasty. Stroke. 1996 Editorial Article GET IT
Times cited: 70
Enhanced nitric oxide production induced by the administration of L-arginine does not inhibit arterial neointimal formation after overwhelming alloimmune injury. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 1996 Academic Article GET IT
Times cited: 3
Expression of interleukin-6 in osteoarthritic chondrocytes and effects of fluid-induced shear on this expression in normal human chondrocytes in vitro. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 1996 Academic Article GET IT
Times cited: 92
Felodipine inhibits intimal lesion formation in the hypercholesterolemic rabbit: differential effects on endothelial and monocyte determinants of atherogenesis. Vascular medicine (London, England). 1996 Academic Article GET IT
Times cited: 3
Regression or progression. Dependency on vascular nitric oxide. Arteriosclerosis, thrombosis, and vascular biology. 1996 Academic Article GET IT
Exposure to shear stress alters endothelial adhesiveness. Role of nitric oxide. Circulation. 1995 Academic Article GET IT
Times cited: 150
Effects of fluid-induced shear on articular chondrocyte morphology and metabolism in vitro. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 1995 Academic Article GET IT
Times cited: 206
Effects of growth factors and L-arginine on ischemic skin flaps in rats. Veterinary surgery : VS. 1995 Academic Article GET IT
Times cited: 6
Clinical trials for claudication. Assessment of exercise performance, functional status, and clinical end points. Vascular Clinical Trialists. Circulation. 1995 Information Resource GET IT
Times cited: 235
The role of coronary angiography and coronary revascularization before noncardiac vascular surgery. JAMA. 1995 Academic Article GET IT
Times cited: 132
Genetic engineering of vein grafts resistant to atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 1995 Academic Article GET IT
Times cited: 183
Discordant effects of dietary L-arginine on vascular structure and reactivity in hypercholesterolemic rabbits. Journal of cardiovascular pharmacology. 1995 Academic Article GET IT
Times cited: 35
Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production. Modulation by potassium channel blockade. The Journal of clinical investigation. 1995 Academic Article GET IT
Times cited: 308
Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. Proceedings of the National Academy of Sciences of the United States of America. 1995 Academic Article GET IT
Times cited: 683
L-arginine attenuates platelet reactivity in hypercholesterolemic rabbits. Arteriosclerosis and thrombosis : a journal of vascular biology. 1994 Academic Article GET IT
Times cited: 111
Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine. Circulation. 1994 Academic Article GET IT
Times cited: 291
Is NO an endogenous antiatherogenic molecule?. Arteriosclerosis and thrombosis : a journal of vascular biology. 1994 Editorial Article GET IT
Times cited: 219
Effect of L-arginine on coronary endothelial function in cardiac transplant recipients. Relation to vessel wall morphology. Circulation. 1994 Academic Article GET IT
Times cited: 121
Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbit. Journal of the American College of Cardiology. 1994 Academic Article GET IT
Times cited: 113
Vascular injury augments adrenergic neurotransmission. Circulation. 1994 Academic Article GET IT
Times cited: 34
Cytoprotective effects of nitric oxide. Circulation. 1993 Editorial Article GET IT
Times cited: 137
Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling. Circulation. 1993 Academic Article GET IT
Times cited: 229
Anti-atherogenic effect of nuts: is the answer NO?. Archives of internal medicine. 1993 Article GET IT
Times cited: 18
Lipid screening: is measuring cholesterol enough?. Cleveland Clinic journal of medicine. 1993 Editorial Article GET IT
Times cited: 1
Vascular biology and medicine in the 1990s: scope, concepts, potentials, and perspectives. Circulation. 1993 Information Resource GET IT
Times cited: 116
L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans. The Journal of clinical investigation. 1992 Academic Article GET IT
Times cited: 716
Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit. The Journal of clinical investigation. 1992 Academic Article GET IT
Times cited: 652
Working group on noncoronary cardiovascular disease and exercise in women. Medicine and science in sports and exercise. 1992 Conference Paper GET IT
Times cited: 4
Endothelium-derived factors and peripheral vascular disease. Cardiovascular clinics. 1992 Information Resource GET IT
Times cited: 9
The case for the speciality of medical angiology. European Working Group on Medical Angiology. VASA. Zeitschrift fur Gefasskrankheiten. 1992 Article GET IT
Times cited: 1
Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. The Journal of clinical investigation. 1991 Academic Article GET IT
Times cited: 451
The case for the specialty of medical angiology. European Working Group on Medical Angiology. International angiology : a journal of the International Union of Angiology. 1991 Article GET IT
Times cited: 3
Hypercholesterolemia enhances macrophage recruitment and dysfunction of regenerated endothelium after balloon injury of the rabbit iliac artery. Circulation. 1991 Academic Article GET IT
Times cited: 68
L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits. The Journal of clinical investigation. 1991 Academic Article GET IT
Times cited: 152
Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta. Circulation. 1991 Academic Article GET IT
Times cited: 306
The hemodynamic effects of S-nitrosocaptopril in anesthetized dogs. The Journal of pharmacology and experimental therapeutics. 1991 Academic Article GET IT
Times cited: 33
Endothelial dysfunction in hypercholesterolemia is corrected by L-arginine. Basic research in cardiology. 1991 Academic Article GET IT
Times cited: 32
L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits. Circulation research. 1990 Academic Article GET IT
Times cited: 234
Sex differences in control of cutaneous blood flow. Circulation. 1990 Academic Article GET IT
Times cited: 129
Flow stimulates endothelial cells to release a nitrovasodilator that is potentiated by reduced thiol. The American journal of physiology. 1990 Academic Article GET IT
Times cited: 222
Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. The Journal of clinical investigation. 1990 Academic Article GET IT
Times cited: 975
Persistent dysfunction of regenerated endothelium after balloon angioplasty of rabbit iliac artery. Circulation. 1990 Academic Article GET IT
Times cited: 151
N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor. Circulation research. 1989 Academic Article GET IT
Times cited: 207
S-nitrosocaptopril. I. Molecular characterization and effects on the vasculature and on platelets. The Journal of pharmacology and experimental therapeutics. 1989 Academic Article GET IT
Times cited: 60
S-nitrosocaptopril. II. Effects on vascular reactivity. The Journal of pharmacology and experimental therapeutics. 1989 Academic Article GET IT
Times cited: 26
Vascular response in diabetes with neuropathic foot lesions. The New England journal of medicine. 1988 Article GET IT
Vasoconstriction induced by ouabain in the canine coronary artery: contribution of adrenergic and nonadrenergic responses. Cardiovascular drugs and therapy. 1988 Academic Article GET IT
Times cited: 8
Endothelium-dependent relaxations in human arteries. Mayo Clinic proceedings. 1987 Academic Article GET IT
Human postjunctional alpha-1 and alpha-2 adrenoceptors: differential distribution in arteries of the limbs. The Journal of pharmacology and experimental therapeutics. 1987 Academic Article GET IT
Times cited: 73
Venous thromboembolism. Acute care. 1986 Information Resource GET IT
Nimodipine and inhibition of alpha adrenergic activation of the isolated canine saphenous vein. The Journal of pharmacology and experimental therapeutics. 1985 Academic Article GET IT
Times cited: 26
Modulation of postjunctional alpha-adrenergic responsiveness by local changes in temperature. Clinical science (London, England : 1979). 1985 Academic Article GET IT
Times cited: 45
Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein. The Journal of pharmacology and experimental therapeutics. 1984 Academic Article GET IT
Times cited: 95
The effect of warming on adrenergic neurotransmission in canine cutaneous vein. Circulation research. 1984 Academic Article GET IT
Times cited: 60

more ...

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Background

education and training

Ph.D., Mayo Graduate School 1985
M.D., Wayne State University School of Medicine 1980
B.A., Cornell University 1976

Contact

full name

John P. Cooke

primary email

jpc2003@med.cornell.edu

VIVO Weill Cornell Medical College

John P. Cooke Professor of Cardiovascular Medicine in Cardiothoracic Surgery

Publications

selected publications

Background

education and training

Contact

full name

primary email