Dr. Pascual's laboratory research has been mostly funded by the National Institutes of Health and generous patient advocacy organizations and virtually spans the entire field of neuroscience: from molecular structure and function (including drug action) or neural physiology and metabolism at the cellular, circuit and whole-brain level, to neurogenetics, all of which is complemented with human studies and clinical trials. Laboratory research greatly influences Dr. Pascual's clinical activities, while patient observations guide his research. The laboratory is home to scientists from very diverse backgrounds and levels of training who devote their efforts to endow both neurology and developmental medicine with a strong scientific basis.

Unusual, large scale projects have included the study of thousands of mice to discover mutants that exceed the limits of biological performance, laying the groundwork for the isolation of the brain from the rest of the body, or following metabolic activity as it crosses biological domains from neural circuits to persons to be leveraged as treatment for certain diseases.

A related area of inquiry uses other methods to provide conceptual clarification and dissolve confusions in two of the least self-critical practical disciplines: neuroscience and medicine.   

Recent clinical research studies 

Recent NIH-funded research projects 

Journal publications (PubMed)

Research Areas: