selected publications
- Protocol for analysis of intracellular conversion of artezomib molecules into new proteasome inhibitors in Plasmodium falciparum parasites. STAR protocols. 2024 Academic Article GET IT
- Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors. Nature communications. 2023 Academic Article GET IT
- Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance. Cell chemical biology. 2023 Academic Article GET IT
- Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell chemical biology. 2023 Academic Article GET IT
- Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II. Journal of medicinal chemistry. 2023 Academic Article GET IT
- Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors. Antimicrobial agents and chemotherapy. 2022 Academic Article GET IT
- Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors. Journal of medicinal chemistry. 2022 Academic Article GET IT
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Can repurposing drugs play a role in malaria control?.
The Journal of experimental medicine.
2021
Academic Article
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Times cited: 3 -
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.
Angewandte Chemie (International ed. in English).
2021
Academic Article
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Times cited: 17 - Telomere length dynamics in response to DNA damage in malaria parasites. iScience. 2021 Academic Article GET IT
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A Histone Methyltransferase Inhibitor Can Reverse Epigenetically Acquired Drug Resistance in the Malaria Parasite Plasmodium falciparum.
Antimicrobial agents and chemotherapy.
2020
Academic Article
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Times cited: 9 -
Vive la Différence: Exploiting the Differences between Rodent and Human Malarias.
Trends in parasitology.
2020
Information Resource
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Times cited: 8 -
Evolution of Host Specificity by Malaria Parasites through Altered Mechanisms Controlling Genome Maintenance.
mBio.
2020
Academic Article
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Times cited: 11 -
Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors.
Journal of medicinal chemistry.
2019
Academic Article
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Times cited: 26 -
Rapid antigen diversification through mitotic recombination in the human malaria parasite Plasmodium falciparum.
PLoS biology.
2019
Academic Article
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Times cited: 32 -
Chromosome End Repair and Genome Stability in Plasmodium falciparum.
mBio.
2017
Academic Article
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Times cited: 19 -
Babesia microti: from Mice to Ticks to an Increasing Number of Highly Susceptible Humans.
Journal of clinical microbiology.
2017
Information Resource
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Times cited: 49 -
Plasmodium falciparum K76T pfcrt Gene Mutations and Parasite Population Structure, Haiti, 2006-2009.
Emerging infectious diseases.
2016
Academic Article
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Times cited: 9 - Cutaneous Leishmaniasis: Current Treatment Practices in the USA for Returning Travelers. Current treatment options in infectious diseases. 2015 Academic Article GET IT
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Origin of robustness in generating drug-resistant malaria parasites.
Molecular biology and evolution.
2014
Academic Article
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Times cited: 34 -
Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity.
Nucleic acids research.
2013
Academic Article
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Times cited: 74 -
Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum.
Molecular microbiology.
2013
Academic Article
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Times cited: 44 -
Antigenic variation and the generation of diversity in malaria parasites.
Current opinion in microbiology.
2012
Information Resource
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Times cited: 36 -
Frequent recombination events generate diversity within the multi-copy variant antigen gene families of Plasmodium falciparum.
International journal for parasitology.
2008
Academic Article
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Times cited: 50 -
[In vitro cultivation of fields isolates of Plasmodium falciparum in Mali].
Bulletin de la Societe de pathologie exotique (1990).
2007
Academic Article
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Times cited: 4 -
A large outbreak of histoplasmosis among American travelers associated with a hotel in Acapulco, Mexico, spring 2001.
The American journal of tropical medicine and hygiene.
2003
Academic Article
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Times cited: 49 -
Cyclic nucleotide signaling in Toxoplasma gondii bradyzoite differentiation.
Infection and immunity.
2001
Academic Article
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Times cited: 63 -
Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa.
Cell.
1997
Academic Article
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Times cited: 324 -
Plasmodium falciparum: isolation of large numbers of parasite clones from infected blood samples.
Experimental parasitology.
1996
Academic Article
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Times cited: 32 -
Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine.
Proceedings of the National Academy of Sciences of the United States of America.
1996
Academic Article
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Times cited: 342 -
An analysis of vincristine-resistance in BHK cells pretreated with 1-beta-D-arabinofuranosylcytosine.
Anticancer research.
1993
Academic Article
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Times cited: 2