Garcia Bonilla, Lidia

Publications

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selected publications

Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke. Nature immunology. 2024 Academic Article GET IT
Essential Role of Endothelial Sphingolipid Biosynthesis in Cerebrovascular Homeostasis. Circulation research. 2023 Academic Article GET IT
Immune compartments at the brain's borders in health and neurovascular diseases. Seminars in immunopathology. 2023 Review GET IT
A preclinical randomized controlled multi-centre trial of anti-interleukin-17A treatment for acute ischaemic stroke. Brain communications. 2023 Academic Article GET IT
Role of microglial and endothelial CD36 in post-ischemic inflammasome activation and interleukin-1β-induced endothelial activation. Brain, behavior, and immunity. 2021 Academic Article GET IT
Times cited: 14
Endothelial S1P₁ Signaling Counteracts Infarct Expansion in Ischemic Stroke. Circulation research. 2020 Academic Article GET IT
Times cited: 68
Endothelium-Macrophage Crosstalk Mediates Blood-Brain Barrier Dysfunction in Hypertension. Hypertension (Dallas, Tex. : 1979). 2020 Academic Article GET IT
Times cited: 89
Endogenous Protection from Ischemic Brain Injury by Preconditioned Monocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2018 Academic Article GET IT
Times cited: 50
Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response. Nature neuroscience. 2018 Academic Article GET IT
Times cited: 222
Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides. Circulation research. 2017 Academic Article GET IT
Times cited: 144
Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension. The Journal of clinical investigation. 2016 Academic Article GET IT
Times cited: 220
Spatio-temporal profile, phenotypic diversity, and fate of recruited monocytes into the post-ischemic brain. Journal of neuroinflammation. 2016 Academic Article GET IT
Times cited: 79
Endothelial CD36 Contributes to Postischemic Brain Injury by Promoting Neutrophil Activation via CSF3. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Academic Article GET IT
Times cited: 46
The role of microglia and myeloid immune cells in acute cerebral ischemia. Frontiers in cellular neuroscience. 2015 Review GET IT
Times cited: 204
Inducible nitric oxide synthase in neutrophils and endothelium contributes to ischemic brain injury in mice. Journal of immunology (Baltimore, Md. : 1950). 2014 Academic Article GET IT
Times cited: 102
Rat middle cerebral artery occlusion is not a suitable model for the study of stroke-induced spontaneous infections. PloS one. 2014 Academic Article GET IT
Times cited: 2
Brain proteomics identifies potential simvastatin targets in acute phase of stroke in a rat embolic model. Journal of neurochemistry. 2014 Academic Article GET IT
Times cited: 16
Immune mechanisms in cerebral ischemic tolerance. Frontiers in neuroscience. 2014 Review GET IT
Times cited: 57
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2013 Academic Article GET IT
Times cited: 75
Combining statins with tissue plasminogen activator treatment after experimental and human stroke: a safety study on hemorrhagic transformation. CNS neuroscience & therapeutics. 2013 Academic Article GET IT
Times cited: 14
Factors secreted by endothelial progenitor cells enhance neurorepair responses after cerebral ischemia in mice. PloS one. 2013 Academic Article GET IT
Times cited: 91
A new method for focal transient cerebral ischaemia by distal compression of the middle cerebral artery. Neuropathology and applied neurobiology. 2012 Academic Article GET IT
Times cited: 30
Citicoline in pre-clinical animal models of stroke: a meta-analysis shows the optimal neuroprotective profile and the missing steps for jumping into a stroke clinical trial. Journal of neurochemistry. 2012 Review GET IT
Times cited: 22
Peroxiredoxin sets the brain on fire after stroke. Nature medicine. 2012 Article GET IT
Times cited: 37
Evidence for the efficacy of statins in animal stroke models: a meta-analysis. Journal of neurochemistry. 2012 Review GET IT
Times cited: 51
VAP-1/SSAO plasma activity and brain expression in human hemorrhagic stroke. Cerebrovascular diseases (Basel, Switzerland). 2011 Academic Article GET IT
Times cited: 32
Effects of acute post-treatment with dipyridamole in a rat model of focal cerebral ischemia. Brain research. 2010 Academic Article GET IT
Times cited: 23
Recommendations guide for experimental animal models in stroke research. Neurologia (Barcelona, Spain). 2010 Academic Article GET IT
Times cited: 11
Plasma VAP-1/SSAO activity predicts intracranial hemorrhages and adverse neurological outcome after tissue plasminogen activator treatment in stroke. Stroke. 2010 Academic Article GET IT
Times cited: 56
Assessment of protein expression levels after transient global cerebral ischemia using an antibody microarray analysis. Neurochemical research. 2010 Academic Article GET IT
Times cited: 8
Triflusal and aspirin have different effects on inflammatory biomarkers measured in patients with acute ischemic stroke. Cerebrovascular diseases (Basel, Switzerland). 2009 Academic Article GET IT
Times cited: 3
Neuronal TIMP-1 release accompanies astrocytic MMP-9 secretion and enhances astrocyte proliferation induced by beta-amyloid 25-35 fragment. Journal of neuroscience research. 2009 Academic Article GET IT
Times cited: 32
Matrix metalloproteinase-13 is activated and is found in the nucleus of neural cells after cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2008 Academic Article GET IT
Times cited: 60
Proteomic characterization of protein phosphatase 1 complexes in ischemia-reperfusion and ischemic tolerance. Proteomics. 2007 Academic Article GET IT
Times cited: 32
Regulatory proteins of eukaryotic initiation factor 2-alpha subunit (eIF2 alpha) phosphatase, under ischemic reperfusion and tolerance. Journal of neurochemistry. 2007 Academic Article GET IT
Times cited: 18
Calpain-induced proteolysis after transient global cerebral ischemia and ischemic tolerance in a rat model. Neurochemical research. 2006 Academic Article GET IT
Times cited: 14
Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK. The Journal of cell biology. 2006 Academic Article GET IT
Times cited: 131
Evidence for a role of second pathophysiological stress in prevention of delayed neuronal death in the hippocampal CA1 region. Neurochemical research. 2005 Academic Article GET IT
Times cited: 57
Ischaemic preconditioning in the rat brain: effect on the activity of several initiation factors, Akt and extracellular signal-regulated protein kinase phosphorylation, and GRP78 and GADD34 expression. Journal of neurochemistry. 2004 Academic Article GET IT
Times cited: 61
Role of protein synthesis in the ischemic tolerance acquisition induced by transient forebrain ischemia in the rat. Neurochemical research. 2003 Academic Article GET IT
Times cited: 54

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Research

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Co-investigator Network

Funding awarded

Immune Privilege, CNS Autoimmunity, and Clostridium perfringens Epsilon Toxin awarded by National Institute of Allergy & Infectious Diseases Co-Investigator 2023 - 2028
The role of dendritic cells in regulating the gut-brain immune axis in ischemic stroke awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2023 - 2028
Dietary sodium, neurovascular dysfunction and cerebrovascular risk awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2021 - 2026
Endothelial Sphingolipid Signaling in Neurovascular Ischemic Injury awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2020 - 2025
Protective monocytes in cerebral ischemic tolerance awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2018 - 2024

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Background

education and training

Ph.D., University of Alcala (Spain) 2006
M.Sc., Universidad Complutense de Madrid (Spain) 2000

Contact

full name

Lidia Garcia Bonilla

primary email

lig2021@med.cornell.edu

VIVO Weill Cornell Medical College

Lidia Garcia Bonilla Assistant Professor of Research in Neuroscience

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email