Zhou, Liangdong

Publications

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selected publications

Diffusion Tensor Imaging Along the Perivascular Space for Characterizing Cerebral Interstitial Fluid Dynamics in Alzheimer's Disease: A Systematic Review and Meta-Analysis. AJNR. American journal of neuroradiology. 2025 Review GET IT
Decreased quantitative transport mapping velocity in the middle cerebral artery-supplied temporal lobe in Alzheimer's disease. Alzheimer's & Dementia. 2025 Academic Article GET IT
Region-informed machine learning model for choroid plexus segmentation in Alzheimer's disease. Frontiers in aging neuroscience. 2025 Academic Article GET IT
PET Imaging of Neurofluids. PET clinics. 2025 Review GET IT
Brain glymphatic fluid mapping in Alzheimer's disease: a human MRI and PET study. Brain communications. 2025 Academic Article GET IT
Divergent neurodegeneration associations with choroid plexus volume and degree of calcification in cognitively normal APOE ε4 carriers and non-carriers. Scientific reports. 2025 Academic Article GET IT
Concordance between Centiloid quantification and visual interpretation of amyloid PET scans across the Alzheimer's disease continuum. AJNR. American journal of neuroradiology. 2025 Academic Article GET IT
Decreased brain interstitial fluid dynamics is associated with risk of Alzheimer's disease-related cognitive decline. Brain research bulletin. 2025 Academic Article GET IT
PET Imaging of Neurofluids. Neuroimaging clinics of North America. 2025 Review GET IT
Diagnostic accuracy of phosphorylated tau217 in detecting Alzheimer's disease pathology among cognitively impaired and unimpaired: A systematic review and meta-analysis. Alzheimer's & Dementia. 2024 Review GET IT
Quantitative transport mapping of multi-delay arterial spin labeling MRI detects early blood perfusion alterations in Alzheimer's disease. Alzheimer's research & therapy. 2024 Academic Article GET IT
Clinical Arterial Spin-Labeling MR Imaging to Screen for Typical and Atypical Neurodegenerative Disease in the New Era of Alzheimer Treatment. AJNR. American journal of neuroradiology. 2024 Academic Article GET IT
Times cited: 3
Brain Fluid Clearance After Traumatic Brain Injury Measured Using Dynamic Positron Emission Tomography. Neurotrauma reports. 2024 Academic Article GET IT
[1-¹¹C]-Butanol Positron Emission Tomography reveals an impaired brain to nasal turbinates pathway in aging amyloid positive subjects. Fluids and barriers of the CNS. 2024 Academic Article GET IT
Quantitative transport mapping of multi-delay arterial spin labeling MRI detects early blood perfusion alteration in Alzheimer's disease. 2024 GET IT
Diffusion Tensor Imaging Along Perivascular Spaces (DTI-ALPS) to Assess Effects of Age, Sex, and Head Size on Interstitial Fluid Dynamics in Healthy Subjects. Journal of Alzheimer's disease reports. 2024 Academic Article GET IT
Times cited: 7
Impaired sleep is associated with tau deposition on ¹⁸F-flortaucipir PET and accelerated cognitive decline, accounting for medications that affect sleep. Journal of the neurological sciences. 2024 Academic Article GET IT
Parenchymal CSF fraction is a measure of brain glymphatic clearance and positively associated with amyloid beta deposition on PET. Alzheimer's & Dementia. 2024 Academic Article GET IT
Times cited: 18
Reduction in Constitutively Activated Auditory Brainstem Microglia in Aging and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024 Academic Article GET IT
Multimodal assessment of brain fluid clearance is associated with amyloid-beta deposition in humans. Journal of neuroradiology = Journal de neuroradiologie. 2023 Academic Article GET IT
Times cited: 20
Association of brain tissue cerebrospinal fluid fraction with age in healthy cognitively normal adults. Frontiers in aging neuroscience. 2023 Academic Article GET IT
Times cited: 13
Choroid Plexus Calcification Correlates with Cortical Microglial Activation in Humans: A Multimodal PET, CT, MRI Study. AJNR. American journal of neuroradiology. 2023 Academic Article GET IT
Times cited: 11
Peripheral immune cell imbalance is associated with cortical beta-amyloid deposition and longitudinal cognitive decline. Scientific reports. 2023 Academic Article GET IT
Times cited: 20
Glymphatic clearance estimated using diffusion tensor imaging along perivascular spaces is reduced after traumatic brain injury and correlates with plasma neurofilament light, a biomarker of injury severity. Brain communications. 2023 Academic Article GET IT
Times cited: 40
Fluid Mechanics Approach to Perfusion Quantification: Vasculature Computational Fluid Dynamics Simulation, Quantitative Transport Mapping (QTM) Analysis of Dynamics Contrast Enhanced MRI, and Application in Nonalcoholic Fatty Liver Disease Classification. IEEE transactions on bio-medical engineering. 2023 Academic Article GET IT
Tau PET following acute TBI: Off-target binding to blood products, tauopathy, or both?. Frontiers in neuroimaging. 2022 Academic Article GET IT
Times cited: 4
Positron Emission Tomography reveals age-associated hypothalamic microglial activation in women. Scientific reports. 2022 Academic Article GET IT
Times cited: 8
Decreased CSF clearance and increased brain amyloid in Alzheimer's disease. Fluids and barriers of the CNS. 2022 Academic Article GET IT
Times cited: 68
Quantitative transport mapping (QTM) for differentiating benign and malignant breast lesion: Comparison with traditional kinetics modeling and semi-quantitative enhancement curve characteristics. Magnetic resonance imaging. 2021 Academic Article GET IT
Times cited: 12
Quantitative transport mapping (QTM) of the kidney with an approximate microvascular network. Magnetic resonance in medicine. 2020 Academic Article GET IT
Times cited: 16
Motoric impairment versus iron deposition gradient in the subthalamic nucleus in Parkinson's disease. Journal of neurosurgery. 2020 Academic Article GET IT
Times cited: 1
Quantitative Susceptibility Mapping (QSM) Algorithms: Mathematical Rationale and Computational Implementations. IEEE transactions on bio-medical engineering. 2017 Academic Article GET IT
Times cited: 27
Electrical impedance spectroscopy-based defect sensing technique in estimating cracks. Sensors (Basel, Switzerland). 2015 Academic Article GET IT
Times cited: 12

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Research

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Co-investigator Network

Funding awarded

Brain fluid clearance and misfolded protein dynamics following traumatic brain injury awarded by National Institute on Aging Co-Investigator 2023 - 2028
CSF Clearance in Sporadic Alzheimer''s Disease Co-Investigator 2019 - 2025

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Background

education and training

Ph.D., Yonsei University (Korea) 2017
B.S., Ocean University of China (China) 2011

Contact

full name

Liangdong Zhou

primary email

liz2018@med.cornell.edu

VIVO Weill Cornell Medical College

Liangdong Zhou Instructor of Biomedical Engineering in Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email