selected publications
- Testing a Model of Care for Patients on Immune Checkpoint Inhibitors Based on Electronic Patient-Reported Outcomes: Protocol for a Randomized Phase II Controlled Trial. JMIR research protocols. 2023 Academic Article GET IT
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Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy.
CPT: pharmacometrics & systems pharmacology.
2023
Academic Article
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Times cited: 5 -
Semiautomated Pipeline to Quantify Tumor Evolution From Real-World Positron Emission Tomography/Computed Tomography Imaging.
JCO clinical cancer informatics.
2023
Academic Article
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Times cited: 2 - Interactive process mining of cancer treatment sequences with melanoma real-world data. Frontiers in oncology. 2023 Academic Article GET IT
- Estimated Costs of the Ipilimumab-Nivolumab Therapy and Related Adverse Events in Metastatic Melanoma. Cancers. 2022 Academic Article GET IT
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A differential process mining analysis of COVID-19 management for cancer patients.
Frontiers in oncology.
2022
Academic Article
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Times cited: 3 -
Safety and Efficacy of Ipilimumab plus Nivolumab and Sequential Selective Internal Radiation Therapy in Hepatic and Extrahepatic Metastatic Uveal Melanoma.
Cancers.
2022
Academic Article
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Times cited: 11 -
Structural Prediction of Peptide-MHC Binding Modes.
Methods in molecular biology (Clifton, N.J.).
2022
Review
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Times cited: 3 - Author Correction: Truly privacy-preserving federated analytics for precision medicine with multiparty homomorphic encryption. 2021 GET IT
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Truly privacy-preserving federated analytics for precision medicine with multiparty homomorphic encryption.
Nature communications.
2021
Academic Article
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Times cited: 88 -
A Graphic Encoding Method for Quantitative Classification of Protein Structure and Representation of Conformational Changes.
IEEE/ACM transactions on computational biology and bioinformatics.
2021
Academic Article
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Times cited: 1 -
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma.
Nature cancer.
2021
Academic Article
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Times cited: 118 -
Turning tumors from cold to inflamed to improve immunotherapy response.
Cancer treatment reviews.
2021
Review
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Times cited: 34 - Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin. Scientific reports. 2021 Academic Article GET IT
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Late-onset and long-lasting immune-related adverse events from immune checkpoint-inhibitors: An overlooked aspect in immunotherapy.
European journal of cancer.
2021
Academic Article
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Times cited: 63 -
Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry.
Biochemistry.
2021
Academic Article
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Times cited: 2 -
What Role Can Process Mining Play in Recurrent Clinical Guidelines Issues? A Position Paper.
International journal of environmental research and public health.
2020
Academic Article
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Times cited: 13 -
SPHN/PHRT - MedCo in Action: Empowering the Swiss Molecular Tumor Board with Privacy-Preserving and Real-Time Patient Discovery.
Studies in health technology and informatics.
2020
Academic Article
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Times cited: 1 -
The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study.
Journal of neuro-oncology.
2019
Academic Article
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Times cited: 5 -
CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8+ T-cell Responses.
Journal of molecular biology.
2019
Academic Article
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Times cited: 6 -
Endpoint-restricted adiabatic free energy dynamics approach for the exploration of biomolecular conformational equilibria.
The Journal of chemical physics.
2018
Academic Article
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Times cited: 10 -
Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT.
Science advances.
2018
Academic Article
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Times cited: 42 -
Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter.
Biophysical journal.
2017
Academic Article
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Times cited: 13 -
Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties.
Biophysical journal.
2017
Academic Article
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Times cited: 34 -
The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β2-Microglobulin through Distinct Binding Sites.
Biochemistry.
2017
Academic Article
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Times cited: 7 -
The Allostery Landscape: Quantifying Thermodynamic Couplings in Biomolecular Systems.
Journal of chemical theory and computation.
2016
Academic Article
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Times cited: 24 -
Allosteric Mechanisms of Molecular Machines at the Membrane: Transport by Sodium-Coupled Symporters.
Chemical reviews.
2016
Information Resource
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Times cited: 49 -
Transport domain unlocking sets the uptake rate of an aspartate transporter.
Nature.
2015
Academic Article
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Times cited: 132 -
Free Energy Reconstruction from Metadynamics or Adiabatic Free Energy Dynamics Simulations.
Journal of chemical theory and computation.
2014
Academic Article
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Times cited: 48 -
How accurately do current force fields predict experimental peptide conformations? An adiabatic free energy dynamics study.
The journal of physical chemistry. B.
2014
Academic Article
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Times cited: 29 -
Structure-Based, Rational Design of T Cell Receptors.
Frontiers in immunology.
2013
Information Resource
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Times cited: 49 -
Heating and flooding: a unified approach for rapid generation of free energy surfaces.
The Journal of chemical physics.
2012
Academic Article
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Times cited: 67 -
Alchemical Free Energy Differences in Flexible Molecules from Thermodynamic Integration or Free Energy Perturbation Combined with Driven Adiabatic Dynamics.
Journal of chemical theory and computation.
2012
Academic Article
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Times cited: 16 -
How T cell receptors interact with peptide-MHCs: a multiple steered molecular dynamics study.
Proteins.
2011
Academic Article
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Times cited: 36 -
SwissParam: a fast force field generation tool for small organic molecules.
Journal of computational chemistry.
2011
Academic Article
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Times cited: 1354 -
Implementation of the CHARMM Force Field in GROMACS: Analysis of Protein Stability Effects from Correction Maps, Virtual Interaction Sites, and Water Models.
Journal of chemical theory and computation.
2010
Academic Article
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Times cited: 755 -
Use of the FACTS solvation model for protein-ligand docking calculations. Application to EADock.
Journal of molecular recognition : JMR.
2010
Academic Article
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Times cited: 27 -
Protein-protein interaction investigated by steered molecular dynamics: the TCR-pMHC complex.
Biophysical journal.
2008
Academic Article
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Times cited: 105 -
On the calculation of velocity-dependent properties in molecular dynamics simulations using the leapfrog integration algorithm.
The Journal of chemical physics.
2007
Academic Article
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Times cited: 87 -
Optical spectra of Cu(II)-azurin by hybrid TDDFT-molecular dynamics simulations.
The journal of physical chemistry. B.
2007
Academic Article
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Times cited: 38 -
The Jarzynski identity derived from general Hamiltonian or non-Hamiltonian dynamics reproducing NVT or NPT ensembles.
The Journal of chemical physics.
2006
Review
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Times cited: 37 -
Statistical mechanical derivation of Jarzynski's identity for thermostated non-Hamiltonian dynamics.
Physical review letters.
2006
Academic Article
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Times cited: 31