Hamieh, Mohamad

Publications

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selected publications

Two Costimulations Are Better Than One: Role of Endogenous CD28 in 4-1BB CAR T Cells. Blood cancer discovery. 2026 Academic Article GET IT
Heart Failure in Lebanon: A Glimpse into the Reality of Growing Burden. Diagnostics (Basel, Switzerland). 2025 Academic Article GET IT
Author Correction: Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells. 2024 GET IT
Times cited: 1
Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies. Nature cancer. 2024 Academic Article GET IT
Programming CAR T Cell Tumor Recognition: Tuned Antigen Sensing and Logic Gating. Cancer discovery. 2023 Academic Article GET IT
Times cited: 116
CD19 CAR antigen engagement mechanisms and affinity tuning. Science immunology. 2023 Academic Article GET IT
Times cited: 52
Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells. Nature biomedical engineering. 2022 Academic Article GET IT
Times cited: 66
Designer protein circuits enable safe cancer immunotherapy. Nature. 2022 Comment GET IT
Times cited: 2
HLA-independent T cell receptors for targeting tumors with low antigen density. Nature medicine. 2022 Academic Article GET IT
Times cited: 149
Generation of Pure Highly Functional Human Anti-Tumor Specific Cytotoxic T Lymphocytes With Stem Cell-Like Memory Features for Melanoma Immunotherapy. Frontiers in immunology. 2021 Academic Article GET IT
Times cited: 5
Immunogenicity of CAR T cells in cancer therapy. Nature reviews. Clinical oncology. 2021 Review GET IT
Times cited: 250
Brucella prosthetic valve endocarditis with septic and cardiogenic shock. 2020 GET IT
Times cited: 3
Presence of T cells directed against CD20-derived peptides in healthy individuals and lymphoma patients. Cancer immunology, immunotherapy : CII. 2019 Academic Article GET IT
Times cited: 5
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape. Nature. 2019 Academic Article GET IT
Times cited: 566
Publisher Correction: Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency. 2019 GET IT
Times cited: 7
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency. Nature medicine. 2018 Academic Article GET IT
Times cited: 450
Low-Dose Radiation Conditioning Enables CAR T Cells to Mitigate Antigen Escape. Molecular therapy : the journal of the American Society of Gene Therapy. 2018 Academic Article GET IT
Times cited: 235
Insights into Chimeric Antigen Receptor Therapy for Chronic Lymphoblastic Leukemia. Trends in molecular medicine. 2018 Comment GET IT
CAR T cell-induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade. Nature medicine. 2018 Academic Article GET IT
Times cited: 1110
Integrating Proteomics and Transcriptomics for Systematic Combinatorial Chimeric Antigen Receptor Therapy of AML. Cancer cell. 2017 Academic Article GET IT
Times cited: 291
The ADAMTS13^1239-1253 peptide is a dominant HLA-DR1-restricted CD4⁺ T-cell epitope. Haematologica. 2017 Academic Article GET IT
Times cited: 11
Identification of a novel PD-L1 positive solid tumor transplantable in HLA-A*0201/DRB1*0101 transgenic mice. Oncotarget. 2017 Academic Article GET IT
Times cited: 5
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection. Nature. 2017 Academic Article GET IT
Times cited: 1536
T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts. Oncotarget. 2016 Academic Article GET IT
Times cited: 164
Correction: Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools. 2016 GET IT
Times cited: 4
Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability. Immunity. 2016 Academic Article GET IT
Times cited: 790
Artificial antigen-presenting cells expressing HLA class II molecules as an effective tool for amplifying human specific memory CD4(+) T cells. Immunology and cell biology. 2016 Academic Article GET IT
Times cited: 18
Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools. PLoS genetics. 2016 Academic Article GET IT
Times cited: 141
The pharmacology of second-generation chimeric antigen receptors. Nature reviews. Drug discovery. 2015 Review GET IT
Times cited: 490
Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy. Cancer research. 2015 Academic Article GET IT
Times cited: 219
Direct Toll-Like Receptor 8 signaling increases the functional avidity of human CD8+ T lymphocytes generated for adoptive T cell therapy strategies. Immunity, inflammation and disease. 2015 Academic Article GET IT
Times cited: 8

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Research

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Co-investigator Network

Funding awarded

Clinical and Translational Science Center - UL1 awarded by National Center for Advancing Translational Sciences Co-Investigator 2022 - 2027

PICI Grant and Main Collaboration Agreement with Multiple Subprojects awarded by Parker Institute for Cancer Immunotherapy Co-Principal Investigator 2024 - 2028
Clinical and Translational Science Center - UL1 awarded by National Center for Advancing Translational Sciences Co-Principal Investigator 2022 - 2027

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Background

education and training

Ph.D., University of Rouen (France) 2014
M.S., University of Rouen (France) 2010
M.S., Lebanese University (Lebanon) 2007
B.S., Lebanese University (Lebanon) 2006

Contact

full name

Mohamad Hamieh

primary email

moh4006@med.cornell.edu

VIVO Weill Cornell Medical College

Mohamad Hamieh Assistant Professor of Immunology in Pediatrics

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email