selected publications
- Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies. Nature cancer. 2024 Academic Article GET IT
- Author Correction: Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells. 2024 GET IT
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Programming CAR T Cell Tumor Recognition: Tuned Antigen Sensing and Logic Gating.
Cancer discovery.
2023
Academic Article
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Times cited: 36 - CD19 CAR antigen engagement mechanisms and affinity tuning. Science immunology. 2023 Academic Article GET IT
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Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells.
Nature biomedical engineering.
2022
Academic Article
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Times cited: 42 -
Designer protein circuits enable safe cancer immunotherapy.
Nature.
2022
Comment
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Times cited: 1 -
HLA-independent T cell receptors for targeting tumors with low antigen density.
Nature medicine.
2022
Academic Article
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Times cited: 84 -
Generation of Pure Highly Functional Human Anti-Tumor Specific Cytotoxic T Lymphocytes With Stem Cell-Like Memory Features for Melanoma Immunotherapy.
Frontiers in immunology.
2021
Academic Article
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Times cited: 2 -
Immunogenicity of CAR T cells in cancer therapy.
Nature reviews. Clinical oncology.
2021
Review
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Times cited: 149 -
Brucella prosthetic valve endocarditis with septic and cardiogenic shock.
2020
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Times cited: 1 -
Presence of T cells directed against CD20-derived peptides in healthy individuals and lymphoma patients.
Cancer immunology, immunotherapy : CII.
2019
Academic Article
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Times cited: 5 -
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape.
Nature.
2019
Academic Article
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Times cited: 424 -
Publisher Correction: Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency.
2019
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Times cited: 6 -
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency.
Nature medicine.
2018
Academic Article
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Times cited: 339 -
Low-Dose Radiation Conditioning Enables CAR T Cells to Mitigate Antigen Escape.
Molecular therapy : the journal of the American Society of Gene Therapy.
2018
Academic Article
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Times cited: 184 - Insights into Chimeric Antigen Receptor Therapy for Chronic Lymphoblastic Leukemia. Trends in molecular medicine. 2018 Comment GET IT
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CAR T cell-induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade.
Nature medicine.
2018
Academic Article
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Times cited: 907 -
Integrating Proteomics and Transcriptomics for Systematic Combinatorial Chimeric Antigen Receptor Therapy of AML.
Cancer cell.
2017
Academic Article
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Times cited: 227 -
The ADAMTS131239-1253 peptide is a dominant HLA-DR1-restricted CD4+ T-cell epitope.
Haematologica.
2017
Academic Article
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Times cited: 11 -
Identification of a novel PD-L1 positive solid tumor transplantable in HLA-A*0201/DRB1*0101 transgenic mice.
Oncotarget.
2017
Academic Article
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Times cited: 4 -
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.
Nature.
2017
Academic Article
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Times cited: 1280 -
T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts.
Oncotarget.
2016
Academic Article
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Times cited: 138 -
Correction: Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools.
2016
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Times cited: 3 -
Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.
Immunity.
2016
Academic Article
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Times cited: 693 -
Artificial antigen-presenting cells expressing HLA class II molecules as an effective tool for amplifying human specific memory CD4(+) T cells.
Immunology and cell biology.
2016
Academic Article
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Times cited: 13 -
Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools.
PLoS genetics.
2016
Academic Article
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Times cited: 127 -
The pharmacology of second-generation chimeric antigen receptors.
Nature reviews. Drug discovery.
2015
Information Resource
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Times cited: 415 -
Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy.
Cancer research.
2015
Academic Article
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Times cited: 190 -
Direct Toll-Like Receptor 8 signaling increases the functional avidity of human CD8+ T lymphocytes generated for adoptive T cell therapy strategies.
Immunity, inflammation and disease.
2015
Academic Article
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Times cited: 5