Insights into Chimeric Antigen Receptor Therapy for Chronic Lymphoblastic Leukemia. uri icon

Overview

abstract

  • In a recent study, Fraietta and colleagues identified chimeric antigen receptor (CAR) T cell biomarkers that may predict the success or failure of CAR therapy in patients with refractory chronic lymphoblastic leukemia (CLL). These findings open new prospects for improving T cell product manufacturing and the management of patients with CLL undergoing T cell-based therapies.

publication date

  • July 4, 2018

Research

keywords

  • Immunotherapy, Adoptive
  • Leukemia, Lymphocytic, Chronic, B-Cell

Identity

Scopus Document Identifier

  • 85049313066

Digital Object Identifier (DOI)

  • 10.1016/j.molmed.2018.06.007

PubMed ID

  • 30149852

Additional Document Info

volume

  • 24

issue

  • 9