selected publications
- Serotonin-1A receptor, a psychiatric disease risk factor, influences offspring immunity via sex-dependent genetic nurture. iScience. 2022 Academic Article GET IT
- Adaptive immune responses in patients requiring revision after Total Knee Arthroplasty. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2022 Academic Article GET IT
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Interleukin-13 Receptor α1-Mediated Signaling Regulates Age-Associated/Autoimmune B Cell Expansion and Lupus Pathogenesis.
Arthritis & rheumatology (Hoboken, N.J.).
2022
Academic Article
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Times cited: 7 -
Molecular mechanisms controlling age-associated B cells in autoimmunity.
Immunological reviews.
2022
Review
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Times cited: 24 -
Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice.
Nature communications.
2021
Academic Article
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Times cited: 50 -
Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis.
eLife.
2020
Academic Article
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Times cited: 12 - Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma. Scientific reports. 2020 Academic Article GET IT
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Control of GM-CSF-Dependent Dendritic Cell Differentiation and Maturation by DEF6 and SWAP-70.
Journal of immunology (Baltimore, Md. : 1950).
2020
Academic Article
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Times cited: 3 -
Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.
The Journal of clinical investigation.
2020
Academic Article
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Times cited: 20 -
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue.
Arthritis research & therapy.
2018
Academic Article
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Times cited: 82 -
Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data.
Arthritis & rheumatology (Hoboken, N.J.).
2018
Academic Article
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Times cited: 138 -
Regulation of age-associated B cells by IRF5 in systemic autoimmunity.
Nature immunology.
2018
Academic Article
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Times cited: 102 -
The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity.
Nature communications.
2017
Academic Article
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Times cited: 47 -
Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.
Journal of immunology (Baltimore, Md. : 1950).
2017
Academic Article
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Times cited: 15 -
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.
Nature.
2017
Academic Article
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Times cited: 745 -
Targeting the RhoA-ROCK pathway to reverse T-cell dysfunction in SLE.
Annals of the rheumatic diseases.
2016
Academic Article
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Times cited: 71 - The RhoA-ROCK pathway in the regulation of T and B cell responses. F1000Research. 2016 Information Resource GET IT
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SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.
PloS one.
2016
Academic Article
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Times cited: 9 -
Regulation of Effector Treg Cells in Murine Lupus.
Arthritis & rheumatology (Hoboken, N.J.).
2016
Academic Article
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Times cited: 18 -
Cigarette smoke inhibits ROCK2 activation in T cells and modulates IL-22 production.
Molecular immunology.
2016
Academic Article
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Times cited: 14 -
IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus.
PloS one.
2015
Academic Article
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Times cited: 16 -
Increased rho kinase activity in temporal artery biopsies from patients with giant cell arteritis.
Rheumatology (Oxford, England).
2014
Academic Article
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Times cited: 15 -
Epigenetics and the IRFs: a complex interplay in the control of immunity and autoimmunity.
Autoimmunity.
2013
Information Resource
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Times cited: 16 -
Enhanced rho-associated protein kinase activation in patients with systemic lupus erythematosus.
Arthritis and rheumatism.
2013
Academic Article
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Times cited: 53 -
Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity.
The Journal of experimental medicine.
2012
Academic Article
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Times cited: 57 -
Administration of fasudil, a ROCK inhibitor, attenuates disease in lupus-prone NZB/W F1 female mice.
Lupus.
2012
Academic Article
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Times cited: 34 -
A murine autoimmune model of rheumatoid arthritis and systemic lupus erythematosus associated with deregulated production of IL-17 and IL-21.
Methods in molecular biology (Clifton, N.J.).
2012
Academic Article
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Times cited: 9 -
Aberrant ROCK activation promotes the development of type I diabetes in NOD mice.
Cellular immunology.
2010
Academic Article
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Times cited: 12 -
Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.
The Journal of clinical investigation.
2010
Academic Article
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Times cited: 193 -
IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?.
Immunological reviews.
2010
Information Resource
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Times cited: 67 -
Regulation of TLR4-mediated signaling by IBP/Def6, a novel activator of Rho GTPases.
Journal of leukocyte biology.
2008
Academic Article
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Times cited: 23 -
IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor.
Immunity.
2008
Academic Article
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Times cited: 165 -
Rho GTPase-mediated pathways in mature CD4+ T cells.
Autoimmunity reviews.
2008
Information Resource
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Times cited: 24 -
A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.
Cancer cell.
2007
Academic Article
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Times cited: 273 -
Estrogen and CD4+ T cells.
Current opinion in rheumatology.
2007
Information Resource
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Times cited: 86 -
Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity.
The Journal of clinical investigation.
2006
Academic Article
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Times cited: 84 -
Enhancer-mediated control of macrophage-specific arginase I expression.
Journal of immunology (Baltimore, Md. : 1950).
2004
Academic Article
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Times cited: 169 -
T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse.
The Journal of biological chemistry.
2003
Academic Article
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Times cited: 65 -
CD95 rapidly clusters in cells of diverse origins.
Cancer biology & therapy.
2003
Academic Article
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Times cited: 49 -
Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system.
Human immunology.
2003
Academic Article
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Times cited: 66 -
Regulation of lymphocyte apoptosis by interferon regulatory factor 4 (IRF-4).
The Journal of experimental medicine.
2003
Academic Article
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Times cited: 26 -
Modulation of T cell cytokine production by interferon regulatory factor-4.
The Journal of biological chemistry.
2002
Academic Article
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Times cited: 84 -
JAK-STAT signaling in asthma.
The Journal of clinical investigation.
2002
Information Resource
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Times cited: 169 -
The role of IRF-4 in B and T cell activation and differentiation.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
2002
Information Resource
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Times cited: 54 -
Stage-specific modulation of IFN-regulatory factor 4 function by Krüppel-type zinc finger proteins.
Journal of immunology (Baltimore, Md. : 1950).
2001
Academic Article
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Times cited: 40 -
Interferon gamma signaling alters the function of T helper type 1 cells.
The Journal of experimental medicine.
2000
Academic Article
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Times cited: 62 -
Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4.
The Journal of experimental medicine.
1999
Academic Article
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Times cited: 108 -
IFN-alpha activates Stat6 and leads to the formation of Stat2:Stat6 complexes in B cells.
Journal of immunology (Baltimore, Md. : 1950).
1999
Academic Article
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Times cited: 68 -
Signaling pathways mediated by the TNF- and cytokine-receptor families target a common cis-element of the IFN regulatory factor 1 promoter.
Journal of immunology (Baltimore, Md. : 1950).
1998
Academic Article
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Times cited: 23 -
Jak-STAT signaling induced by the v-abl oncogene.
Science (New York, N.Y.).
1995
Academic Article
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Times cited: 313 -
Interleukin 4 signals through two related pathways.
Proceedings of the National Academy of Sciences of the United States of America.
1995
Academic Article
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Times cited: 82 -
Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells.
Science (New York, N.Y.).
1995
Academic Article
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Times cited: 274 -
Gamma chain-associated cytokine receptors signal through distinct transducing factors.
The Journal of biological chemistry.
1995
Academic Article
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Times cited: 30 -
Intravenous pulse cyclophosphamide treatment of severe lupus nephritis: a prospective five-year study.
Clinical nephrology.
1994
Academic Article
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Times cited: 99 -
STF-IL-4: a novel IL-4-induced signal transducing factor.
The EMBO journal.
1994
Academic Article
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Times cited: 185 -
T-BAM/CD40-L on helper T lymphocytes augments lymphokine-induced B cell Ig isotype switch recombination and rescues B cells from programmed cell death.
Journal of immunology (Baltimore, Md. : 1950).
1994
Academic Article
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Times cited: 106