selected publications
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Emerging translational science discoveries, clonal approaches, and treatment trends in chronic myeloproliferative neoplasms.
Hematological oncology.
2019
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Times cited: 4 -
Efficacy of MEK inhibition in patients with histiocytic neoplasms.
Nature.
2019
Academic Article
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Times cited: 269 -
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis.
Blood.
2018
Academic Article
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Times cited: 34 -
Single-agent dabrafenib for BRAFV600E-mutated histiocytosis.
Haematologica.
2018
Academic Article
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Times cited: 39 -
Phase 2 trial of a multivalent WT1 peptide vaccine (galinpepimut-S) in acute myeloid leukemia.
Blood advances.
2018
Academic Article
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Times cited: 125 -
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
The Journal of clinical investigation.
2018
Academic Article
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Times cited: 60 -
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.
Cancer cell.
2017
Academic Article
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Times cited: 182 -
Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms.
Haematologica.
2017
Letter
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Times cited: 18 -
High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.
Blood.
2017
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Times cited: 117 -
Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells.
Blood.
2017
Academic Article
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Times cited: 100 -
Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.
Cell stem cell.
2017
Academic Article
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Times cited: 116 -
The use of Erwinia asparaginase for adult patients with acute lymphoblastic leukemia after pegaspargase intolerance.
Leukemia research.
2016
Academic Article
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Times cited: 18 -
Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis.
The Journal of experimental medicine.
2016
Academic Article
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Times cited: 129 -
Telomere length and associations with somatic mutations and clinical outcomes in acute myeloid leukemia.
Leukemia research.
2016
Academic Article
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Times cited: 15 -
Mutational correlates of response to hypomethylating agent therapy in acute myeloid leukemia.
Haematologica.
2016
Article
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Times cited: 34 -
Bisphosphonates in Langerhans Cell Histiocytosis: An International Retrospective Case Series.
Mediterranean journal of hematology and infectious diseases.
2016
Academic Article
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Times cited: 22 -
Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia.
Haematologica.
2016
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Times cited: 85 -
Contemporary insights into the pathogenesis and treatment of chronic myeloproliferative neoplasms.
Leukemia & lymphoma.
2016
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Times cited: 6 -
Clinical response to ruxolitinib in CSF3R T618-mutated chronic neutrophilic leukemia.
Annals of hematology.
2016
Article
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Times cited: 29 - Genetic analysis of five children with essential thrombocytosis identified mutations in cancer-associated genes with roles in transcriptional regulation. Haematologica. 2016 Article GET IT
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Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting.
Blood.
2016
Academic Article
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Times cited: 255 -
Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2015
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Times cited: 55 -
An international data set for CMML validates prognostic scoring systems and demonstrates a need for novel prognostication strategies.
Blood cancer journal.
2015
Academic Article
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Times cited: 111 -
CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.
Cancer cell.
2015
Academic Article
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Times cited: 129 -
Clinical and molecular genetic characterization of myelofibrosis.
Current opinion in hematology.
2015
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Times cited: 13 -
JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.
Cancer discovery.
2015
Academic Article
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Times cited: 248 -
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Cell reports.
2014
Academic Article
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Times cited: 225 -
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms.
Proceedings of the National Academy of Sciences of the United States of America.
2014
Academic Article
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Times cited: 247 -
Novel insights into the biology and treatment of chronic myeloproliferative neoplasms.
Leukemia & lymphoma.
2014
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Times cited: 4 -
Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders.
Cancer discovery.
2014
Academic Article
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Times cited: 117 -
JAK2 inhibitors do not affect stem cells present in the spleens of patients with myelofibrosis.
Blood.
2014
Academic Article
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Times cited: 30 -
Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease.
Blood.
2014
Academic Article
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Times cited: 207 -
Integrating genomics into prognostic models for AML.
Seminars in hematology.
2014
Academic Article
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Times cited: 6 -
A primer on genomic and epigenomic alterations in the myeloproliferative neoplasms.
Best practice & research. Clinical haematology.
2014
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Times cited: 15 -
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia.
Science translational medicine.
2014
Academic Article
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Times cited: 112 -
Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis.
Blood.
2014
Academic Article
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Times cited: 348 -
Pathogenesis and management of acute myeloid leukemia that has evolved from a myeloproliferative neoplasm.
Current opinion in hematology.
2014
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Times cited: 28 -
Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms.
Blood.
2014
Academic Article
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Times cited: 96 -
Leveraging cancer genome information in hematologic malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2013
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Times cited: 14 -
Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome.
Blood.
2012
Academic Article
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Times cited: 190 -
Finding a needle in a haystack: whole genome sequencing and mutation discovery in murine models.
The Journal of clinical investigation.
2011
Article
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Times cited: 3