Ghobrial, R.

Publications

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selected publications

Epigenetically modifying the Foxp3 locus for generation of stable antigen-specific Tregs as cellular therapeutics. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2020 Academic Article GET IT
Times cited: 13
International Liver Transplantation Consensus Statement on End-stage Liver Disease Due to Nonalcoholic Steatohepatitis and Liver Transplantation. Transplantation. 2019 Academic Article GET IT
Times cited: 36
Inhibition of RhoA and mTORC2/Rictor by Fingolimod (FTY720) induces p21-activated kinase 1, PAK-1 and amplifies podosomes in mouse peritoneal macrophages. Immunobiology. 2018 Academic Article GET IT
Times cited: 13
Screening RhoA/ROCK inhibitors for the ability to prevent chronic rejection of mouse cardiac allografts. Transplant immunology. 2018 Academic Article GET IT
Times cited: 12
Conquering combined thoracic organ and liver transplantation: indications and outcomes for heart-liver and lung-liver transplantation. Current opinion in organ transplantation. 2018 Information Resource GET IT
Times cited: 8
Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4⁺ T Cell Dysfunction. Immunity. 2017 Academic Article GET IT
Times cited: 76
Longitudinal assessment of T cell inhibitory receptors in liver transplant recipients and their association with posttransplant infections. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2017 Academic Article GET IT
Times cited: 11
TNF superfamily receptor OX40 triggers invariant NKT cell pyroptosis and liver injury. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 47
Macrophages and RhoA Pathway in Transplanted Organs. Results and problems in cell differentiation. 2017 Article GET IT
Times cited: 6
Dissonant response of M0/M2 and M1 bone-marrow-derived macrophages to RhoA pathway interference. Cell and tissue research. 2016 Academic Article GET IT
Times cited: 14
Macrophage/monocyte-specific deletion of Ras homolog gene family member A (RhoA) downregulates fractalkine receptor and inhibits chronic rejection of mouse cardiac allografts. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2016 Academic Article GET IT
Times cited: 33
The Emerging Role of Nanotechnology in Cell and Organ Transplantation. Transplantation. 2016 Information Resource GET IT
Times cited: 35
The Costimulatory Receptor OX40 Inhibits Interleukin-17 Expression through Activation of Repressive Chromatin Remodeling Pathways. Immunity. 2016 Academic Article GET IT
Times cited: 59
Graft-Infiltrating Macrophages Adopt an M2 Phenotype and Are Inhibited by Purinergic Receptor P2X7 Antagonist in Chronic Rejection. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2016 Academic Article GET IT
Times cited: 53
Mouse macrophage polarity and ROCK1 activity depend on RhoA and non-apoptotic Caspase 3. Experimental cell research. 2016 Academic Article GET IT
Times cited: 23
Efficacy and cost-effectiveness of voriconazole prophylaxis for prevention of invasive aspergillosis in high-risk liver transplant recipients. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2016 Academic Article GET IT
Times cited: 15
ROCK inhibition impedes macrophage polarity and functions. Cellular immunology. 2015 Academic Article GET IT
Times cited: 30
The Evolving Roles of Memory Immune Cells in Transplantation. Transplantation. 2015 Information Resource GET IT
Times cited: 17
GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nature communications. 2015 Academic Article GET IT
Times cited: 89
Pericytes, microvasular dysfunction, and chronic rejection. Transplantation. 2015 Information Resource GET IT
Times cited: 22
The newly found functions of MTOC in immunological response. Journal of leukocyte biology. 2013 Information Resource GET IT
Times cited: 17
Combined lung and liver transplantation: analysis of a single-center experience. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2013 Academic Article GET IT
Times cited: 46
Abrogation of chronic rejection in rat model system involves modulation of the mTORC1 and mTORC2 pathways. Transplantation. 2013 Academic Article GET IT
Times cited: 14
Leveraging nanochannels for universal, zero-order drug delivery in vivo. Journal of controlled release : official journal of the Controlled Release Society. 2013 Academic Article GET IT
Times cited: 60
Memory T cells in transplantation - progress and challenges. Current opinion in organ transplantation. 2013 Information Resource GET IT
Times cited: 23
Pre-transplant utilization of sorafenib is not associated with increased complications after liver transplantation. Transplant international : official journal of the European Society for Organ Transplantation. 2013 Academic Article GET IT
Times cited: 21
Inverse relationship between TCTP/RhoA and p53 /cyclin A/actin expression in ovarian cancer cells. Folia histochemica et cytobiologica. 2012 Academic Article GET IT
Times cited: 17
Liver transplantation for hepatocellular carcinoma: past, present, and future. Clinical transplants. 2012 Information Resource GET IT
Times cited: 2
Polarity and asymmetry during mouse oogenesis and oocyte maturation. Results and problems in cell differentiation. 2012 Information Resource GET IT
Times cited: 13
Critical care issues in patients after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2011 Information Resource GET IT
Times cited: 65
Allochimeric molecules and mechanisms in abrogation of cardiac allograft rejection. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2011 Academic Article GET IT
Times cited: 3
Efficacy of CT angiography for preoperative vascular mapping in adult to adult living related liver transplant donors. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2011 Academic Article GET IT
Times cited: 3
Analysis of liver transplant outcomes for United Network for Organ Sharing recipients 60 years old or older identifies multiple model for end-stage liver disease-independent prognostic factors. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2010 Academic Article GET IT
Times cited: 59
Downregulation of RhoA and changes in T cell cytoskeleton correlate with the abrogation of allograft rejection. Transplant immunology. 2010 Academic Article GET IT
Times cited: 8
Intragraft gene expression profile associated with the induction of tolerance by allochimeric MHC I in the rat heart transplantation model. Genesis (New York, N.Y. : 2000). 2010 Academic Article GET IT
Times cited: 3
Down regulation of genes involved in T cell polarity and motility during the induction of heart allograft tolerance by allochimeric MHC I. PloS one. 2009 Academic Article GET IT
Times cited: 9
Predicting poor outcome following hepatectomy: analysis of 2313 hepatectomies in the NSQIP database. HPB : the official journal of the International Hepato Pancreato Biliary Association. 2009 Academic Article GET IT
Times cited: 160
Intragraft selection of the T cell receptor repertoire by class I MHC sequences in tolerant recipients. PloS one. 2009 Academic Article GET IT
Times cited: 3
Vascular complications of orthotopic liver transplantation: experience in more than 4,200 patients. Journal of the American College of Surgeons. 2009 Academic Article GET IT
Times cited: 312
Longterm outcomes for whole and segmental liver grafts in adult and pediatric liver transplant recipients: a 10-year comparative analysis of 2,988 cases. Journal of the American College of Surgeons. 2009 Academic Article GET IT
Times cited: 108
Timing of referral impacts surgical outcomes in patients undergoing repair of bile duct injuries. HPB : the official journal of the International Hepato Pancreato Biliary Association. 2009 Academic Article GET IT
Times cited: 46
Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma. Molecular medicine (Cambridge, Mass.). 2008 Academic Article GET IT
Times cited: 247
Incidence and severity of acute cellular rejection in recipients undergoing adult living donor or deceased donor liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2008 Academic Article GET IT
Times cited: 141
Recipient morbidity after living and deceased donor liver transplantation: findings from the A2ALL Retrospective Cohort Study. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2008 Academic Article GET IT
Times cited: 240
Pretransplant variables associated with quality of life in liver transplant recipients. Liver international : official journal of the International Association for the Study of the Liver. 2008 Academic Article GET IT
Times cited: 8
Donor morbidity after living donation for liver transplantation. Gastroenterology. 2008 Academic Article GET IT
Times cited: 358
Does race influence outcomes after primary liver transplantation? A 23-year experience with 2,700 patients. Journal of the American College of Surgeons. 2008 Academic Article GET IT
Times cited: 14
Recurrence of hepatocellular carcinoma following liver transplantation: a review of preoperative and postoperative prognostic indicators. Archives of surgery (Chicago, Ill. : 1960). 2008 Information Resource GET IT
Times cited: 205
Antiviral prophylaxis and recurrence of hepatocellular carcinoma following liver transplantation in patients with hepatitis B. Transplantation proceedings. 2007 Academic Article GET IT
Times cited: 30
Comparison of hepatitis C histological recurrence rates and patient survival between split and deceased donor liver transplantation. Transplantation proceedings. 2007 Academic Article GET IT
Times cited: 9
Class I MHC allochimeric presentation of composite immunogenic and self epitopes induces tolerance to genetically diverse rat strains. Cellular immunology. 2007 Academic Article GET IT
Times cited: 6
Liver transplantation for HELLP syndrome. The American surgeon. 2007 Academic Article GET IT
Times cited: 37
Improvement in survival associated with adult-to-adult living donor liver transplantation. Gastroenterology. 2007 Academic Article GET IT
Times cited: 175
Employment and quality of life in liver transplant recipients. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2007 Academic Article GET IT
Times cited: 65
Liver transplantation criteria for hepatocellular carcinoma should be expanded: a 22-year experience with 467 patients at UCLA. Annals of surgery. 2007 Academic Article GET IT
Times cited: 407
Predictors of hyperkalemia in the prereperfusion, early postreperfusion, and late postreperfusion periods during adult liver transplantation. Anesthesia and analgesia. 2007 Academic Article GET IT
Times cited: 64
Outcome of liver transplantation in septuagenarians: a single-center experience. Archives of surgery (Chicago, Ill. : 1960). 2007 Academic Article GET IT
Times cited: 48
Anemia in liver transplant recipients undergoing antiviral treatment for recurrent hepatitis C. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2007 Academic Article GET IT
Times cited: 38
Hepatocellular carcinoma recurrence and death following living and deceased donor liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2007 Academic Article GET IT
Times cited: 233
Postresection hepatic failure: successful treatment with liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2007 Academic Article GET IT
Times cited: 32
Predictors of outcomes after pediatric liver transplantation: an analysis of more than 800 cases performed at a single institution. Journal of the American College of Surgeons. 2007 Academic Article GET IT
Times cited: 77
Effect of nonviral factors on hepatitis C recurrence after liver transplantation. Annals of surgery. 2006 Academic Article GET IT
Times cited: 49
Incisional hernia after liver transplantation. Journal of the American College of Surgeons. 2006 Academic Article GET IT
Times cited: 66
Long-term analysis of combined liver and kidney transplantation at a single center. Archives of surgery (Chicago, Ill. : 1960). 2006 Academic Article GET IT
Times cited: 149
Prevalence and risk factors for diabetes mellitus in moderate term survivors of liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2006 Academic Article GET IT
Times cited: 52
Portocaval hemitransposition in pediatric liver transplant recipients: a single-center experience. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2006 Academic Article GET IT
Times cited: 11
Optimal utilization of donor grafts with extended criteria: a single-center experience in over 1000 liver transplants. Annals of surgery. 2006 Academic Article GET IT
Times cited: 247
The MELD score in advanced liver disease: association with clinical portal hypertension and mortality. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. 2006 Academic Article GET IT
Times cited: 11
Budd-Chiari syndrome. Clinics in liver disease. 2006 Information Resource GET IT
Times cited: 38
Preoperative characteristics and intraoperative transfusion and vasopressor requirements in patients with low vs. high MELD scores. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2006 Academic Article GET IT
Times cited: 75
Inhibition of chronic rejection by antibody induced vascular accommodation in fully allogeneic heart allografts. Transplantation. 2005 Academic Article GET IT
Times cited: 13
Mortality predictors in liver transplant recipients with recurrent hepatitis C cirrhosis. Liver international : official journal of the International Association for the Study of the Liver. 2005 Academic Article GET IT
Times cited: 19
Safety and efficacy of a single bolus administration of recombinant factor VIIa in liver transplantation due to chronic liver disease. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2005 Academic Article GET IT
Times cited: 182
MELD fails to measure quality of life in liver transplant candidates. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2005 Academic Article GET IT
Times cited: 84
Predictors of survival after liver transplantation for hepatocellular carcinoma associated with Hepatitis C. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2004 Academic Article GET IT
Times cited: 81
Giant cavernous liver hemangiomas: effect of operative approach on outcome. Archives of surgery (Chicago, Ill. : 1960). 2004 Academic Article GET IT
Times cited: 86
Outcomes of acute rejection after interferon therapy in liver transplant recipients. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2004 Academic Article GET IT
Times cited: 87
Macrovesicular hepatic steatosis in living related liver donors: correlation between CT and histologic findings. Radiology. 2004 Academic Article GET IT
Times cited: 270
A model to predict the development of mental status changes of unclear cause after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2003 Academic Article GET IT
Times cited: 31
Outcomes of hepatitis C- and hepatitis B core antibody-positive grafts in orthotopic liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2003 Academic Article GET IT
Times cited: 64
Treatment for recurrent hepatitis C. Minerva chirurgica. 2003 Information Resource GET IT
Times cited: 2
Hepatitis C positive grafts may be used in orthotopic liver transplantation: a matched analysis. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003 Academic Article GET IT
Times cited: 66
Hepatocellular carcinoma screening in patients waiting for liver transplantation: a decision analytic model. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2003 Academic Article GET IT
Times cited: 62
Acquired hemophilia A after liver transplantation: a case report. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2003 Academic Article GET IT
Times cited: 23
MELD score predicts 1-year patient survival post-orthotopic liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2003 Academic Article GET IT
Times cited: 173
Operative parameters that predict the outcomes of hepatic transplantation. Journal of the American College of Surgeons. 2003 Academic Article GET IT
Times cited: 35
Discordance between ALT values and fibrosis in liver transplant recipients treated with ribavirin for recurrent hepatitis C. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003 Academic Article GET IT
Times cited: 16
Posttransplant administration of allochimeric major histocompatibility complex class-I-molecules induces true transplantation tolerance. Transplantation. 2003 Academic Article GET IT
Times cited: 11
Conversion from intravenous to intramuscular hepatitis B immune globulin in combination with lamivudine is safe and cost-effective in patients receiving long-term prophylaxis to prevent hepatitis B recurrence after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2003 Academic Article GET IT
Times cited: 85
Changing faces of liver transplantation: partial-liver grafts for adults. Journal of hepato-biliary-pancreatic surgery. 2003 Information Resource GET IT
Times cited: 29
Donor and recipient outcomes in right lobe adult living donor liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2002 Academic Article GET IT
Times cited: 107
Retrospective analysis of the results of liver transplantation for adults with severe hepatopulmonary syndrome. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2002 Academic Article GET IT
Is it cost-effective to treat recurrent hepatitis C infection in orthotopic liver transplantation patients?. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2002 Academic Article GET IT
New era of liver transplantation for hepatitis B: a 17-year single-center experience. Annals of surgery. 2002 Academic Article GET IT
Times cited: 117
Technical and logistical considerations of in situ split-liver transplantation for two adults: Part II. Creation of left segment I-IV and right segment V-VIII grafts. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2002 Academic Article GET IT
Times cited: 26
Early graft function after pediatric liver transplantation: comparison between in situ split liver grafts and living-related liver grafts. Transplantation. 2001 Academic Article GET IT
Times cited: 65
Liver transplantation for cholangiocellular carcinoma: analysis of a single-center experience and review of the literature. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2001 Information Resource GET IT
Technical and logistical considerations of in situ split-liver transplantation for two adults: Part I. Creation of left segment II, III, IV and right segment I, V-VIII grafts. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2001 Academic Article GET IT
Times cited: 25
A cost-effectiveness analysis of biliary anastomosis with or without T-tube after orthotopic liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2001 Academic Article GET IT
Times cited: 49
Technical challenges of hepatic venous outflow reconstruction in right lobe adult living donor liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2001 Academic Article GET IT
Times cited: 97
Amelioration of hepatic ischemia/reperfusion injury with intercellular adhesion molecule-1 antisense oligodeoxynucleotides. Transplantation proceedings. 2001 Academic Article GET IT
Times cited: 7
Liver transplantation at Dumont-UCLA Transplant Center: an experience with over 3,000 cases. Clinical transplants. 2001 Academic Article GET IT
Times cited: 11
An efficacy and cost-effectiveness analysis of combination hepatitis B immune globulin and lamivudine to prevent recurrent hepatitis B after orthotopic liver transplantation compared with hepatitis B immune globulin monotherapy. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2000 Academic Article GET IT
Times cited: 210
Endoscopic management of biliary leaks after T-tube removal in liver transplant recipients: nasobiliary drainage versus biliary stenting. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2000 Academic Article GET IT
Times cited: 49
Predictors of survival after In vivo split liver transplantation: analysis of 110 consecutive patients. Annals of surgery. 2000 Academic Article GET IT
Times cited: 113
Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury. The Journal of clinical investigation. 1999 Academic Article GET IT
Times cited: 471
A simple model to estimate survival after retransplantation of the liver. Transplantation. 1999 Academic Article GET IT
Times cited: 92
Th1 and Th2 cytokines in organ transplantation: paradigm lost?. Critical reviews in immunology. 1999 Information Resource GET IT
Times cited: 76
Mycophenolate mofetil: effects on clinical transplantation. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 1998 Academic Article GET IT
Liver transplantation for decompensated cirrhosis after jejunoileal bypass: a strategy for management. Transplantation. 1998 Academic Article GET IT
Times cited: 22
Mycophenolate mofetil. Pharmacotherapy. 1997 Information Resource GET IT
Times cited: 104
Long-term survival after retransplantation of the liver. Annals of surgery. 1997 Academic Article GET IT
Times cited: 200
In situ splitting of the cadaveric liver for transplantation. Transplantation. 1997 Academic Article GET IT
Times cited: 162
Synergistic mechanisms by which sirolimus and cyclosporin inhibit rat heart and kidney allograft rejection. Clinical and experimental immunology. 1997 Academic Article GET IT
Times cited: 90
Induction of transplantation tolerance by chimeric donor/recipient class I RT1.Aa molecules. Transplantation. 1996 Academic Article GET IT
Times cited: 41
Kinetics of in vitro immune responses of T and B cells during tolerance induction by sirolimus. Annals of transplantation. 1996 Academic Article GET IT
Times cited: 4
Membrane-bound or soluble truncated RT1.Aa rat class I major histocompatibility antigens induce specific alloimmunity. Transplantation. 1995 Academic Article GET IT
Times cited: 10
Immunosuppressive agents. The Surgical clinics of North America. 1994 Information Resource GET IT
Times cited: 37
Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats. Journal of immunology (Baltimore, Md. : 1950). 1994 Academic Article GET IT
Times cited: 64
Effect of atrial natriuretic peptide on urine flow and glomerular filtration during acute renal allograft rejection. The Journal of urology. 1993 Academic Article GET IT
The mechanism of unresponsiveness to allografts induced by rapamycin and rapamycin/cyclosporine treatment in rats. Transplantation. 1993 Academic Article GET IT
Times cited: 24
Concomitant placement of percutaneous endoscopic gastrostomy and jejunostomy. Surgical endoscopy. 1992 Academic Article GET IT
Times cited: 8
Percutaneous endoscopic gastrostomy with jejunal extension: a new technique. The American journal of gastroenterology. 1992 Academic Article GET IT
Times cited: 29
In vivo use of monoclonal antibodies against murine T cell antigens. Clinical immunology and immunopathology. 1989 Academic Article GET IT
Times cited: 49
Failure to induce chimerism or tolerance in mice with monoclonal anti-T cell antibodies plus allogeneic bone marrow infusion. Transplantation proceedings. 1988 Academic Article GET IT
Times cited: 3
Prevention of alloantibody formation after skin grafting without prolongation of graft survival by anti-L3T4 in vivo. Transplantation. 1988 Academic Article GET IT
Times cited: 42

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Background

education and training

Ph.D., University of Texas Health Sciences Center, Houston 1994
M.D., Cairo University Faculty of Medicine (Egypt) 1980

Contact

full name

R. Ghobrial

VIVO Weill Cornell Medical College

R. Ghobrial Professor of Surgery

Publications

selected publications

Background

education and training

Contact

full name