Vardhana, Santosha Adipudi

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selected publications

Host tissue factors predict immune surveillance and therapeutic outcomes in gastric cancer. Cancer immunology research. 2025 Academic Article GET IT
Leucine zipper-based immunomagnetic purification of CAR T cells displaying multiple receptors. Nature biomedical engineering. 2024 Academic Article GET IT
Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2024 Academic Article GET IT
Author Correction: Duvelisib plus romidepsin in relapsed/refractory T cell lymphomas: a phase 1b/2a trial. 2024 GET IT
Differences in Ancestry and Presence of Gastric Precursor Lesions in Individuals With Young- and Average-Onset Gastric Cancer. Cancer medicine. 2024 Academic Article GET IT
Limited stage high grade B-cell lymphoma with MYC, BCL2 and/or BCL6 rearrangements: BCL2 rearrangements drives the poor outcomes. Blood cancer journal. 2024 Letter GET IT
Disappearing Signet Ring Cell Adenocarcinoma in Gastric Cancer Patients. Annals of surgical oncology. 2024 Academic Article GET IT
Feasibility and Efficacy of Sentinel Lymph Node Mapping in Gastric Cancer. Annals of surgical oncology. 2024 Academic Article GET IT
Intratumoral T-cell composition predicts epcoritamab-based treatment efficacy in B-cell non-Hodgkin lymphomas. 2024 GET IT
Duvelisib plus romidepsin in relapsed/refractory T cell lymphomas: a phase 1b/2a trial. Nature medicine. 2024 Academic Article GET IT
Consideration of a Novel Surgical Approach in the Management of Gastric Adenocarcinoma and Proximal Polyposis Syndrome. 2024 GET IT
Somatic mutations in FAS pathway increase hemophagocytic lymphohistiocytosis risk in T- and/or NK-cell lymphoma patients. Blood advances. 2024 Academic Article GET IT
Gemcitabine plus pembrolizumab after checkpoint blockade failure as a strategy in multiply relapsed Hodgkin lymphoma. British journal of haematology. 2023 Letter GET IT
Retrospective characterization of nodal marginal zone lymphoma. Blood advances. 2023 Review GET IT
TP53 mutations identify high-risk events for peripheral T-cell lymphoma treated with CHOP-based chemotherapy. Blood advances. 2023 Academic Article GET IT
Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells. Nature genetics. 2023 Academic Article GET IT
Times cited: 23
Unique Genomic Alterations and Microbial Profiles Identified in Patients With Gastric Cancer of African, European, and Asian Ancestry: A Novel Path for Precision Oncology. Annals of surgery. 2023 Academic Article GET IT
High-throughput interrogation of immune responses using the Human Immune Profiling Pipeline. STAR protocols. 2023 Academic Article GET IT
Bispecific antibodies for the treatment of B-cell lymphoma: promises, unknowns, and opportunities. Blood. 2023 Review GET IT
Times cited: 104
Risk of Lymph Node Metastasis in T1b Gastric Cancer: An International Comprehensive Analysis from the Global Gastric Group (G3) Alliance. Annals of surgery. 2023 Academic Article GET IT
Times cited: 9
Discordant SARS-CoV-2 spike protein receptor binding domain IgG and neutralization after B-cell depletion. Haematologica. 2022 Academic Article GET IT
SARS-CoV-2 in immunocompromised individuals. Immunity. 2022 Review GET IT
Times cited: 72
A Novel Microbiome Signature in Gastric Cancer: A Two Independent Cohort Retrospective Analysis. Annals of surgery. 2022 Academic Article GET IT
Times cited: 29
Long and persistent COVID-19 in patients with hematologic malignancies: from bench to bedside. Current opinion in infectious diseases. 2022 Review GET IT
Times cited: 20
Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence. Cancer cell. 2022 Academic Article GET IT
Times cited: 170
Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses. Cancer cell. 2022 Academic Article GET IT
Times cited: 37
Understanding T cell responses to COVID-19 is essential for informing public health strategies. Science immunology. 2022 Review GET IT
Times cited: 100
Activity of AZD7442 (tixagevimab-cilgavimab) against Omicron SARS-CoV-2 in patients with hematologic malignancies. Cancer cell. 2022 Letter GET IT
Times cited: 77
Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease. Blood. 2022 Academic Article GET IT
Times cited: 27
Vive la Résistance: T-cell Immunity in the Protection against SARS-CoV-2 Infection. Cancer discovery. 2022 Editorial Article GET IT
Magnesium for T cells: strong to the finish!. Trends in immunology. 2022 Comment GET IT
Times cited: 2
Challenges and opportunities in 2021. Nature cancer. 2021 Academic Article GET IT
Times cited: 1
Prolonged SARS-CoV-2 Infection in Patients with Lymphoid Malignancies. Cancer discovery. 2021 Academic Article GET IT
Times cited: 94
Phase II biomarker-driven study of ruxolitinib demonstrates effectiveness of JAK/STAT targeting in T-cell lymphomas. Blood. 2021 Academic Article GET IT
Metabolic regulation of the cancer-immunity cycle. Trends in immunology. 2021 Review GET IT
Times cited: 42
Disease- and Therapy-Specific Impact on Humoral Immune Responses to COVID-19 Vaccination in Hematologic Malignancies. Blood cancer discovery. 2021 Comment GET IT
Times cited: 58
Predictors of Humoral Response to SARS-CoV-2 Vaccination after Hematopoietic Cell Transplantation and CAR T-cell Therapy. Blood cancer discovery. 2021 Academic Article GET IT
Times cited: 47
Phase II Trial of Pembrolizumab Plus Gemcitabine, Vinorelbine, and Liposomal Doxorubicin as Second-Line Therapy for Relapsed or Refractory Classical Hodgkin Lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2021 Academic Article GET IT
Times cited: 145
CD8⁺ T cells contribute to survival in patients with COVID-19 and hematologic cancer. Nature medicine. 2021 Academic Article GET IT
Times cited: 373
Oncologic immunomodulatory agents in patients with cancer and COVID-19. Scientific reports. 2021 Academic Article GET IT
Times cited: 13
What Should Clinicians Do When a Patient's Autonomy Undermines Her Being Treated Equitably?. AMA journal of ethics. 2021 Academic Article GET IT
Times cited: 6
Translation in amino-acid-poor environments is limited by tRNA^Gln charging. eLife. 2020 Academic Article GET IT
Times cited: 35
Favorable outcomes of COVID-19 in recipients of hematopoietic cell transplantation. The Journal of clinical investigation. 2020 Academic Article GET IT
Times cited: 105
Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen. Nature immunology. 2020 Academic Article GET IT
Times cited: 312
Leveraging insights into cancer metabolism-a symposium report. Annals of the New York Academy of Sciences. 2019 Review GET IT
Times cited: 3
Glutamine independence is a selectable feature of pluripotent stem cells. Nature metabolism. 2019 Academic Article GET IT
Times cited: 47
Cancer Metabolism Drives a Stromal Regenerative Response. Cell metabolism. 2019 Review GET IT
Times cited: 88
Strategies for Recognizing and Managing Immune-Mediated Adverse Events in the Treatment of Hodgkin Lymphoma with Checkpoint Inhibitors. The oncologist. 2018 Information Resource GET IT
Times cited: 7
Outcomes of Relapsed and Refractory Primary Mediastinal (Thymic) Large B Cell Lymphoma Treated with Second-Line Therapy and Intent to Transplant. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2018 Academic Article GET IT
Times cited: 38
Pilot trial of ibrutinib in patients with relapsed or refractory T-cell lymphoma. Blood advances. 2018 Academic Article GET IT
Times cited: 18
Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity. Nature cell biology. 2018 Academic Article GET IT
Times cited: 41
Outcomes of primary refractory diffuse large B-cell lymphoma (DLBCL) treated with salvage chemotherapy and intention to transplant in the rituximab era. British journal of haematology. 2016 Academic Article GET IT
Times cited: 43
The immune microenvironment in Hodgkin lymphoma: T cells, B cells, and immune checkpoints. Haematologica. 2016 Information Resource GET IT
Times cited: 87
Impact of Prophylactic Levofloxacin on Rates of Bloodstream Infection and Fever in Neutropenic Patients with Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2015 Academic Article GET IT
Times cited: 48
Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo. European journal of immunology. 2013 Academic Article GET IT
Times cited: 25
T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse. Frontiers in immunology. 2012 Academic Article GET IT
Times cited: 64
Mitochondrial and plasma membrane pools of stomatin-like protein 2 coalesce at the immunological synapse during T cell activation. PloS one. 2012 Academic Article GET IT
Times cited: 37
Self-reactive human CD4 T cell clones form unusual immunological synapses. The Journal of experimental medicine. 2012 Academic Article GET IT
Times cited: 72
Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster. Immunity. 2010 Academic Article GET IT
Times cited: 133
Functional anatomy of T cell activation and synapse formation. Annual review of immunology. 2010 Review GET IT
Times cited: 370
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proceedings of the National Academy of Sciences of the United States of America. 2009 Academic Article GET IT
Times cited: 158
The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells. Molecular biology of the cell. 2009 Academic Article GET IT
Times cited: 62
The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells. The Journal of cell biology. 2009 Academic Article GET IT
Times cited: 90
T cell antigen receptor signaling and immunological synapse stability require myosin IIA. Nature immunology. 2009 Academic Article GET IT
Times cited: 186
T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta. Journal of immunology (Baltimore, Md. : 1950). 2008 Academic Article GET IT
Times cited: 91
Supported Planar Bilayers for the Formation of Study of Immunological Synapses and Kinapse. Journal of visualized experiments : JoVE. 2008 Academic Article GET IT
Times cited: 12
Modulation of T cell activation by stomatin-like protein 2. Journal of immunology (Baltimore, Md. : 1950). 2008 Academic Article GET IT
Times cited: 41
TNFA-308G>A polymorphism influences the TNF-alpha response to altered vaginal flora. European journal of obstetrics, gynecology, and reproductive biology. 2006 Academic Article GET IT
Times cited: 19
Association of a maternal CD14 -159 gene polymorphism with preterm premature rupture of membranes and spontaneous preterm birth in multi-fetal pregnancies. Journal of reproductive immunology. 2006 Academic Article GET IT
Times cited: 23
Clara cell protein 16 concentration in mid-trimester amniotic fluid: association with fetal gender, fetal G>A +38 CC16 gene polymorphism and pregnancy outcome. Journal of reproductive immunology. 2005 Academic Article GET IT
Times cited: 12
Association between fetal interleukin-1 receptor antagonist gene polymorphism and unexplained fetal death. American journal of obstetrics and gynecology. 2005 Academic Article GET IT
Times cited: 19
A single nucleotide A>G polymorphism at position -670 in the Fas gene promoter: relationship to preterm premature rupture of fetal membranes in multifetal pregnancies. American journal of obstetrics and gynecology. 2005 Academic Article GET IT
Times cited: 27
Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women. European journal of obstetrics, gynecology, and reproductive biology. 2004 Academic Article GET IT
Times cited: 92
Ethnic differences of polymorphisms in cytokine and innate immune system genes in pregnant women. Obstetrics and gynecology. 2004 Academic Article GET IT
Times cited: 58
Interleukin-4 and -10 gene polymorphisms and spontaneous preterm birth in multifetal gestations. American journal of obstetrics and gynecology. 2004 Academic Article GET IT
Times cited: 55
Beta2-adrenergic receptor gene polymorphisms and pregnancy outcome. Journal of perinatal medicine. 2004 Academic Article GET IT
Times cited: 43
Polymorphism in intron 2 of the fetal interleukin-1 receptor antagonist genotype influences midtrimester amniotic fluid concentrations of interleukin-1beta and interleukin-1 receptor antagonist and pregnancy outcome. American journal of obstetrics and gynecology. 2003 Academic Article GET IT
Times cited: 54
Interleukin-1 receptor antagonist gene polymorphism and multifetal pregnancy outcome. American journal of obstetrics and gynecology. 2003 Academic Article GET IT
Times cited: 37

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Background

education and training

M.D., New York University School of Medicine 2011
Ph.D., New York University 2009
B.A., University of Pennsylvania 2002

Contact

full name

Santosha Adipudi Vardhana

VIVO Weill Cornell Medical College

Santosha Adipudi Vardhana Assistant Professor of Medicine

Publications

selected publications

Background

education and training

Contact

full name

Phone

Publications

selected publications

Background

education and training

Contact

full name