The many faces of the anti-COVID immune response. Academic Article uri icon

Overview

abstract

  • The novel 2019 strain of coronavirus is a source of profound morbidity and mortality worldwide. Compared with recent viral outbreaks, COVID-19 infection has a relatively high mortality rate, the reasons for which are not entirely clear. Furthermore, treatment options for COVID-19 infection are currently limited. In this Perspective, we explore the contributions of the innate and adaptive immune systems to both viral control as well as toxicity during COVID-19 infections and offer suggestions to both understand and therapeutically modulate anti-COVID immunity.

publication date

  • June 1, 2020

Research

keywords

  • Betacoronavirus
  • Coronavirus Infections
  • Pneumonia, Viral

Identity

PubMed Central ID

  • PMC7191310

Scopus Document Identifier

  • 85084327344

Digital Object Identifier (DOI)

  • 10.1084/jem.20200678

PubMed ID

  • 32353870

Additional Document Info

volume

  • 217

issue

  • 6