selected publications
- Clinical benefit with tebentafusp in a patient with GNAQ mutant metastatic blue nevus-associated melanoma. 2024 GET IT
- Concurrent SOS1 and MEK suppression inhibits signaling and growth of NF1-null melanoma. Cell reports. Medicine. 2024 Academic Article GET IT
- Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma. The New England journal of medicine. 2024 Academic Article GET IT
- Pharmacologic LDH inhibition redirects intratumoral glucose uptake and improves antitumor immunity in solid tumor models. The Journal of clinical investigation. 2024 Academic Article GET IT
- TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models. Molecular therapy. Oncology. 2024 Academic Article GET IT
- Durable complete response in a patient with leptomeningeal melanoma after treatment with dabrafenib, trametinib, and nivolumab. 2024 GET IT
- Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model. Frontiers in oncology. 2024 Academic Article GET IT
- Intermittent MEK inhibition with GITR co-stimulation rescues T-cell function for increased efficacy with CTLA-4 blockade in solid tumor models. Cancer immunology research. 2024 Academic Article GET IT
- Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment. Nature medicine. 2024 Academic Article GET IT
- Early on-treatment assessment of T-cells, cytokines and tumor DNA with adaptively-dosed nivolumab + ipilimumab: final results from the phase 2 ADAPT-IT study. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024 Academic Article GET IT
- Having the cake and eating it? Clofazimine boosts immunotherapy while limiting side effects. Cancer cell. 2024 Academic Article GET IT
- Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies. Nature cancer. 2024 Academic Article GET IT
- The side effect registry immuno-oncology (SERIO) - A tool for systematic analysis of immunotherapy-induced side effects. European journal of cancer. 2023 Academic Article GET IT
- Phase Ib trial of phenformin in patients with V600-mutated melanoma receiving dabrafenib and trametinib. Cancer research communications. 2023 Academic Article GET IT
- APR-246 increases tumor antigenicity independent of p53. Life science alliance. 2023 Academic Article GET IT
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Tumor dynamics in patients with solid tumors treated with pembrolizumab beyond disease progression.
Cancer cell.
2023
Academic Article
GET IT
Times cited: 1 - MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma. Cancer cell. 2023 Academic Article GET IT
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Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer.
Nature.
2023
Academic Article
GET IT
Times cited: 387 -
OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs.
The Journal of experimental medicine.
2023
Academic Article
GET IT
Times cited: 4 - RECISTv1.1 progression in oncology: Shades of gray. Cancer cell. 2023 Academic Article GET IT
- Beyond the 5-year milestone: Long-term survivorship of melanoma patients treated off-trial with anti-PD-1. Pigment cell & melanoma research. 2023 Academic Article GET IT
- Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma. Cancer cell. 2023 Academic Article GET IT
- Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer. Nature genetics. 2023 Academic Article GET IT
- Eganelisib, a First-in-Class PI3K-γ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
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T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants.
Cell.
2023
Academic Article
GET IT
Times cited: 1 - Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade. Cancer cell. 2023 Academic Article GET IT
- Harnessing imaging tools to guide immunotherapy trials: summary from the National Cancer Institute Cancer Imaging Steering Committee workshop. The Lancet. Oncology. 2023 Review GET IT
- Decision-Making and Health-Related Quality of Life in Patients with Melanoma Considering Adjuvant Immunotherapy. The oncologist. 2023 Academic Article GET IT
- The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer. Immunity. 2022 Academic Article GET IT
- Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant. NPJ vaccines. 2022 Academic Article GET IT
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Clinical implications of T cell exhaustion for cancer immunotherapy.
Nature reviews. Clinical oncology.
2022
Review
GET IT
Times cited: 323 - Immune-Related Adverse Events Among COVID-19-Vaccinated Patients With Cancer Receiving Immune Checkpoint Blockade. Journal of the National Comprehensive Cancer Network : JNCCN. 2022 Academic Article GET IT
- Combination dabrafenib and trametinib versus combination nivolumab and ipilimumab for patients with advanced BRAF-mutant melanoma: The DREAMseq Trial - ECOG-ACRIN EA6134. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Academic Article GET IT
- Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade. The Journal of clinical investigation. 2022 Academic Article GET IT
- Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine. Science translational medicine. 2022 Academic Article GET IT
- Pilot Trial of Arginine Deprivation Plus Nivolumab and Ipilimumab in Patients with Metastatic Uveal Melanoma. Cancers. 2022 Academic Article GET IT
- Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions. The Journal of experimental medicine. 2022 Academic Article GET IT
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Neoantigen quality predicts immunoediting in survivors of pancreatic cancer.
Nature.
2022
Academic Article
GET IT
Times cited: 93 - Fundamental immune-oncogenicity trade-offs define driver mutation fitness. Nature. 2022 Academic Article GET IT
- Proton Pump Inhibitor Use and Efficacy of Nivolumab and Ipilimumab in Advanced Melanoma. Cancers. 2022 Academic Article GET IT
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Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma.
Nature communications.
2022
Academic Article
GET IT
Times cited: 49 -
Anatomic position determines oncogenic specificity in melanoma.
Nature.
2022
Academic Article
GET IT
Times cited: 4 - Reply to T. Olivier et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Letter GET IT
- Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism. Science advances. 2022 Academic Article GET IT
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Ipilimumab alone or in combination with nivolumab in patients with advanced melanoma who have progressed or relapsed on PD-1 blockade: clinical outcomes and translational biomarker analyses.
Journal for immunotherapy of cancer.
2022
Academic Article
GET IT
Times cited: 27 - In vivo optical imaging-guided targeted sampling for precise diagnosis and molecular pathology. Scientific reports. 2021 Academic Article GET IT
- Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2021 Academic Article GET IT
- Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer. Communications biology. 2021 Academic Article GET IT
- Efficacy and safety of vedolizumab and infliximab treatment for immune-mediated diarrhea and colitis in patients with cancer: a two-center observational study. Journal for immunotherapy of cancer. 2021 Academic Article GET IT
- Treatment-free survival over extended follow-up of patients with advanced melanoma treated with immune checkpoint inhibitors in CheckMate 067. Journal for immunotherapy of cancer. 2021 Academic Article GET IT
- Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness. JCI insight. 2021 Academic Article GET IT
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Enhancing immunotherapy in cancer by targeting emerging immunomodulatory pathways.
Nature reviews. Clinical oncology.
2021
Review
GET IT
Times cited: 3 - Long-term outcomes in patients with advanced melanoma who had initial stable disease with pembrolizumab in KEYNOTE-001 and KEYNOTE-006. European journal of cancer. 2021 Academic Article GET IT
- Elucidating mechanisms of antitumor immunity mediated by live oncolytic vaccinia and heat-inactivated vaccinia. Journal for immunotherapy of cancer. 2021 Academic Article GET IT
- LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade. Science translational medicine. 2021 Academic Article GET IT
- CD8-targeted PET Imaging of Tumor Infiltrating T cells in Patients with Cancer: A Phase I First-in-Human Study of 89Zr-Df-IAB22M2C, a Radiolabeled anti-CD8 Minibody. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2021 Academic Article GET IT
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TMB and Inflammatory Gene Expression Associated with Clinical Outcomes following Immunotherapy in Advanced Melanoma.
Cancer immunology research.
2021
Academic Article
GET IT
Times cited: 1 -
Evidence generation and reproducibility in cell and gene therapy research: A call to action.
Molecular therapy. Methods & clinical development.
2021
Editorial Article
GET IT
Times cited: 9 - Reply to: Combining TNF blockade with immune checkpoint inhibitors in patients with cancer. Nature reviews. Rheumatology. 2021 Article GET IT
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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.
Cell.
2021
Academic Article
GET IT
Times cited: 146 - Eradicating micrometastases with immune checkpoint blockade: Strike while the iron is hot. Cancer cell. 2021 Academic Article GET IT
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Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity.
Cancer cell.
2021
Academic Article
GET IT
Times cited: 111 -
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors.
Immunity.
2021
Academic Article
GET IT
Times cited: 2 -
CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer.
Nature medicine.
2021
Academic Article
GET IT
Times cited: 354 -
Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.
Cancer discovery.
2021
Academic Article
GET IT
Times cited: 168 -
A phase 1 study of NY-ESO-1 vaccine + anti-CTLA4 antibody Ipilimumab (IPI) in patients with unresectable or metastatic melanoma.
Oncoimmunology.
2021
Academic Article
GET IT
Times cited: 13 -
TNF in the era of immune checkpoint inhibitors: friend or foe?.
Nature reviews. Rheumatology.
2021
Information Resource
GET IT
Times cited: 93 -
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours.
Nature.
2021
Academic Article
GET IT
Times cited: 235 -
Therapeutic Implications of Detecting MAPK-Activating Alterations in Cutaneous and Unknown Primary Melanomas.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2021
Academic Article
GET IT
Times cited: 31 - Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma. Cell reports. 2021 Academic Article GET IT
- Checkpoint Blockade in Melanoma Patients With Underlying Chronic Lymphocytic Leukemia. Journal of immunotherapy (Hagerstown, Md. : 1997). 2021 Academic Article GET IT
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Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma.
European journal of cancer.
2020
Academic Article
GET IT
Times cited: 64 -
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.
Cancer cell.
2020
Academic Article
GET IT
Times cited: 200 -
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications.
2020
Academic Article
GET IT
Times cited: 236 -
Determinants of COVID-19 disease severity in patients with cancer.
Nature medicine.
2020
Academic Article
GET IT
Times cited: 468 -
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Nature medicine.
2020
Academic Article
GET IT
Times cited: 213 -
The future of cancer immunotherapy: microenvironment-targeting combinations.
Cell research.
2020
Academic Article
GET IT
Times cited: 505 -
Impact of PD-1 Blockade on Severity of COVID-19 in Patients with Lung Cancers.
Cancer discovery.
2020
Academic Article
GET IT
Times cited: 199 -
Quality of life in long-term survivors of advanced melanoma treated with checkpoint inhibitors.
Journal for immunotherapy of cancer.
2020
Academic Article
GET IT
Times cited: 34 -
ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity.
Nature.
2020
Academic Article
GET IT
Times cited: 246 -
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Nature immunology.
2020
Academic Article
GET IT
Times cited: 401 -
Long-Term Outcomes and Responses to Retreatment in Patients With Melanoma Treated With PD-1 Blockade.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2020
Academic Article
GET IT
Times cited: 146 -
Absolute lymphocyte count as a prognostic biomarker for overall survival in patients with advanced melanoma treated with ipilimumab.
Melanoma research.
2020
Academic Article
GET IT
Times cited: 22 -
Safety of Inactivated Influenza Vaccine in Cancer Patients Receiving Immune Checkpoint Inhibitors.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2020
Academic Article
GET IT
Times cited: 86 -
Survival Outcomes After Metastasectomy in Melanoma Patients Categorized by Response to Checkpoint Blockade.
Annals of surgical oncology.
2019
Academic Article
GET IT
Times cited: 40 -
First-in-Humans Imaging with 89Zr-Df-IAB22M2C Anti-CD8 Minibody in Patients with Solid Malignancies: Preliminary Pharmacokinetics, Biodistribution, and Lesion Targeting.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2019
Academic Article
GET IT
Times cited: 173 -
Five-Year Survival and Correlates Among Patients With Advanced Melanoma, Renal Cell Carcinoma, or Non-Small Cell Lung Cancer Treated With Nivolumab.
JAMA oncology.
2019
Academic Article
GET IT
Times cited: 417 -
Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.
The New England journal of medicine.
2019
Academic Article
GET IT
Times cited: 787 -
Intravitreous Cutaneous Metastatic Melanoma in the Era of Checkpoint Inhibition: Unmasking and Masquerading.
Ophthalmology.
2019
Academic Article
GET IT
Times cited: 23 -
Selective inhibition of low-affinity memory CD8+ T cells by corticosteroids.
The Journal of experimental medicine.
2019
Academic Article
GET IT
Times cited: 87 -
Treatment-Free Survival: A Novel Outcome Measure of the Effects of Immune Checkpoint Inhibition-A Pooled Analysis of Patients With Advanced Melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2019
Academic Article
GET IT
Times cited: 61 -
Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade.
Cell.
2019
Academic Article
GET IT
Times cited: 295 -
Adjuvant ipilimumab versus placebo after complete resection of stage III melanoma: long-term follow-up results of the European Organisation for Research and Treatment of Cancer 18071 double-blind phase 3 randomised trial.
European journal of cancer.
2019
Academic Article
GET IT
Times cited: 55 -
PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance.
Nature immunology.
2019
Academic Article
GET IT
Times cited: 220 -
In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors.
The Journal of clinical investigation.
2019
Academic Article
GET IT
Times cited: 34 -
Rational design of anti-GITR-based combination immunotherapy.
Nature medicine.
2019
Academic Article
GET IT
Times cited: 172 -
Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.
Cell reports.
2019
Academic Article
GET IT
Times cited: 54 -
Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade.
JAMA oncology.
2019
Academic Article
GET IT
Times cited: 465 -
Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001.
Annals of oncology : official journal of the European Society for Medical Oncology.
2019
Academic Article
GET IT
Times cited: 652 -
Immunotherapy of Melanoma: Facts and Hopes.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Information Resource
GET IT
Times cited: 195 -
Potentiating vascular-targeted photodynamic therapy through CSF-1R modulation of myeloid cells in a preclinical model of prostate cancer.
Oncoimmunology.
2019
Academic Article
GET IT
Times cited: 15 -
Myocarditis Surveillance in Patients with Advanced Melanoma on Combination Immune Checkpoint Inhibitor Therapy: The Memorial Sloan Kettering Cancer Center Experience.
The oncologist.
2019
Article
GET IT
Times cited: 32 -
Adverse events 2.0-Let us get SERIOs: New reporting for adverse event outcomes needed in the era of immunooncology.
European journal of cancer.
2019
Article
GET IT
Times cited: 7 -
Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy.
Cancer immunology, immunotherapy : CII.
2018
Conference Paper
GET IT
Times cited: 5 -
Prognostic value of baseline metabolic tumor volume measured on 18F-fluorodeoxyglucose positron emission tomography/computed tomography in melanoma patients treated with ipilimumab therapy.
European journal of nuclear medicine and molecular imaging.
2018
Academic Article
GET IT
Times cited: 78 -
18F-FDG PET/CT for Monitoring of Ipilimumab Therapy in Patients with Metastatic Melanoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2018
Academic Article
GET IT
Times cited: 131 -
Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial.
The Lancet. Oncology.
2018
Academic Article
GET IT
Times cited: 551 -
An Antitumor Immune Response Is Evoked by Partial-Volume Single-Dose Radiation in 2 Murine Models.
International journal of radiation oncology, biology, physics.
2018
Academic Article
GET IT
Times cited: 72 -
Strategies for Predicting Response to Checkpoint Inhibitors.
Current hematologic malignancy reports.
2018
Information Resource
GET IT
Times cited: 25 -
The hallmarks of successful anticancer immunotherapy.
Science translational medicine.
2018
Information Resource
GET IT
Times cited: 204 -
Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small-cell lung carcinoma: a proposal for quantitative immune-related pathologic response criteria (irPRC).
Annals of oncology : official journal of the European Society for Medical Oncology.
2018
Academic Article
GET IT
Times cited: 351 -
MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma.
Science translational medicine.
2018
Academic Article
GET IT
Times cited: 170 -
Lysis-independent potentiation of immune checkpoint blockade by oncolytic virus.
Oncotarget.
2018
Academic Article
GET IT
Times cited: 24 -
Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins.
Cancer discovery.
2018
Academic Article
GET IT
Times cited: 263 -
Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Cancer cell.
2018
Academic Article
GET IT
Times cited: 115 -
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.
Cancer discovery.
2018
Academic Article
GET IT
Times cited: 1098 -
Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
GET IT
Times cited: 232 -
Neoadjuvant PD-1 Blockade in Resectable Lung Cancer.
The New England journal of medicine.
2018
Academic Article
GET IT
Times cited: 1448 -
Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.
Cell.
2018
Academic Article
GET IT
Times cited: 116 -
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.
Cancer cell.
2018
Academic Article
GET IT
Times cited: 780 -
Efficacy and Safety Outcomes in Patients With Advanced Melanoma Who Discontinued Treatment With Nivolumab and Ipilimumab Because of Adverse Events: A Pooled Analysis of Randomized Phase II and III Trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
GET IT
Times cited: 338 -
Emerging Concepts for Immune Checkpoint Blockade-Based Combination Therapies.
Cancer cell.
2018
Information Resource
GET IT
Times cited: 375 -
Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody.
PloS one.
2018
Academic Article
GET IT
Times cited: 19 -
Cancer immunotherapy using checkpoint blockade.
Science (New York, N.Y.).
2018
Information Resource
GET IT
Times cited: 4387 -
PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy.
The Journal of clinical investigation.
2018
Academic Article
GET IT
Times cited: 99 -
Alterations in DNA Damage Response and Repair Genes as Potential Marker of Clinical Benefit From PD-1/PD-L1 Blockade in Advanced Urothelial Cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
GET IT
Times cited: 404 -
Peripheral blood clinical laboratory variables associated with outcomes following combination nivolumab and ipilimumab immunotherapy in melanoma.
Cancer medicine.
2018
Academic Article
GET IT
Times cited: 89 - Altered self: the not-so-neo-antigens. Nature reviews. Immunology. 2018 Article GET IT
-
Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy.
Molecular therapy : the journal of the American Society of Gene Therapy.
2018
Academic Article
GET IT
Times cited: 112 -
Immune-Modified Response Evaluation Criteria In Solid Tumors (imRECIST): Refining Guidelines to Assess the Clinical Benefit of Cancer Immunotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
GET IT
Times cited: 138 -
Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors.
Immunity.
2018
Academic Article
GET IT
Times cited: 90 -
Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
GET IT
Times cited: 1062 -
Robust Antitumor Responses Result from Local Chemotherapy and CTLA-4 Blockade.
Cancer immunology research.
2018
Academic Article
GET IT
Times cited: 107 -
Durable Complete Response After Discontinuation of Pembrolizumab in Patients With Metastatic Melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2017
Academic Article
GET IT
Times cited: 197 -
Nivolumab and Ipilimumab in Advanced Melanoma.
The New England journal of medicine.
2017
Article
GET IT
Times cited: 8 -
Shared cancer neoantigens: Making private matters public.
The Journal of experimental medicine.
2017
Article
GET IT
Times cited: 43 -
A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy.
Nature.
2017
Academic Article
GET IT
Times cited: 475 -
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.
Nature.
2017
Academic Article
GET IT
Times cited: 841 -
Nivolumab for Patients With Advanced Melanoma Treated Beyond Progression: Analysis of 2 Phase 3 Clinical Trials.
JAMA oncology.
2017
Academic Article
GET IT
Times cited: 140 -
Future cancer research priorities in the USA: a Lancet Oncology Commission.
The Lancet. Oncology.
2017
Information Resource
GET IT
Times cited: 154 -
Melanoma brain metastases treated with stereotactic radiosurgery and concurrent pembrolizumab display marked regression; efficacy and safety of combined treatment.
Journal for immunotherapy of cancer.
2017
Academic Article
GET IT
Times cited: 94 -
Langerhans-type dendritic cells electroporated with TRP-2 mRNA stimulate cellular immunity against melanoma: Results of a phase I vaccine trial.
Oncoimmunology.
2017
Academic Article
GET IT
Times cited: 23 -
Four-month course of adjuvant dabrafenib in patients with surgically resected stage IIIC melanoma characterized by a BRAFV600E/K mutation.
Oncotarget.
2017
Academic Article
GET IT
Times cited: 9 -
Pooled Analysis Safety Profile of Nivolumab and Ipilimumab Combination Therapy in Patients With Advanced Melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2017
Academic Article
GET IT
Times cited: 121 -
Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.
The New England journal of medicine.
2017
Academic Article
GET IT
Times cited: 2797 -
Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.
Science signaling.
2017
Academic Article
GET IT
Times cited: 104 -
Health-related quality of life results from the phase III CheckMate 067 study.
European journal of cancer.
2017
Academic Article
GET IT
Times cited: 76 -
Pilot study of safety and feasibility of DNA microseeding for treatment of spontaneous canine melanoma.
Veterinary medicine and science.
2017
Academic Article
GET IT
Times cited: 9 -
Intratumoral delivery of inactivated modified vaccinia virus Ankara (iMVA) induces systemic antitumor immunity via STING and Batf3-dependent dendritic cells.
Science immunology.
2017
Academic Article
GET IT
Times cited: 90 -
Chromatin states define tumour-specific T cell dysfunction and reprogramming.
Nature.
2017
Academic Article
GET IT
Times cited: 627 -
Checkpoint inhibition and melanoma: Considerations in treating the older adult.
Journal of geriatric oncology.
2017
Information Resource
GET IT
Times cited: 26 -
T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.
Nature.
2017
Academic Article
GET IT
Times cited: 1221 -
Neutrophil to Lymphocyte Ratio is Associated With Outcome During Ipilimumab Treatment.
EBioMedicine.
2017
Academic Article
GET IT
Times cited: 82 -
iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics.
The Lancet. Oncology.
2017
Information Resource
GET IT
Times cited: 1699 -
Antibody-mediated thyroid dysfunction during T-cell checkpoint blockade in patients with non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology.
2017
Academic Article
GET IT
Times cited: 503 -
Patient perspectives on ipilimumab across the melanoma treatment trajectory.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2017
Academic Article
GET IT
Times cited: 19 -
Combination immunotherapy: a road map.
Journal for immunotherapy of cancer.
2017
Information Resource
GET IT
Times cited: 305 -
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications.
2017
Academic Article
GET IT
Times cited: 111 -
Peripheral CD8 effector-memory type 1 T-cells correlate with outcome in ipilimumab-treated stage IV melanoma patients.
European journal of cancer.
2017
Academic Article
GET IT
Times cited: 83 -
Health-related quality of life with adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): secondary outcomes of a multinational, randomised, double-blind, phase 3 trial.
The Lancet. Oncology.
2017
Academic Article
GET IT
Times cited: 82 -
Cancer immunotherapy - immune checkpoint blockade and associated endocrinopathies.
Nature reviews. Endocrinology.
2017
Information Resource
GET IT
Times cited: 520 -
An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity.
Molecular therapy oncolytics.
2017
Academic Article
GET IT
Times cited: 69 -
Validation of Anti-Mouse PDL-1 Goat Polyclonal Antibody Staining with Mouse PDL-1 In Situ Hybridization on Adjacent Sections of Cell Pellets and Mouse Tumors.
Methods in molecular biology (Clifton, N.J.).
2017
Article
GET IT
Times cited: 1 -
Thinking Critically About Classifying Adverse Events: Incidence of Pancreatitis in Patients Treated With Nivolumab + Ipilimumab.
Journal of the National Cancer Institute.
2016
Academic Article
GET IT
Times cited: 56 -
Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology-molecular associations: clinical and biological implications.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2016
Academic Article
GET IT
Times cited: 70 -
Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade.
Cancer immunology research.
2016
Academic Article
GET IT
Times cited: 130 -
Safety Profile of Nivolumab Monotherapy: A Pooled Analysis of Patients With Advanced Melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
Academic Article
GET IT
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Nature.
2016
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Efficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
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T-Cell Therapy Using Interleukin-21-Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
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Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
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An Open-Label, Dose-Escalation Phase I Study of Anti-TYRP1 Monoclonal Antibody IMC-20D7S for Patients with Relapsed or Refractory Melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
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Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy.
The New England journal of medicine.
2016
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Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016
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Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells.
Cancer immunology research.
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Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial.
The Lancet. Oncology.
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Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy.
Cancer immunology research.
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A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling.
Clinical cancer research : an official journal of the American Association for Cancer Research.
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Proportions of blood-borne Vδ1+ and Vδ2+ T-cells are associated with overall survival of melanoma patients treated with ipilimumab.
European journal of cancer.
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Definite regression of cutaneous melanoma metastases upon addition of topical contact sensitizer diphencyprone to immune checkpoint inhibitor treatment.
Experimental dermatology.
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In-depth tissue profiling using multiplexed immunohistochemical consecutive staining on single slide.
Science immunology.
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Prognosis of Mucosal, Uveal, Acral, Nonacral Cutaneous, and Unknown Primary Melanoma From the Time of First Metastasis.
The oncologist.
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Clinicopathological features of acute kidney injury associated with immune checkpoint inhibitors.
Kidney international.
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A phase 2 trial of everolimus and pasireotide long-acting release in patients with metastatic uveal melanoma.
Melanoma research.
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Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient.
The Journal of experimental medicine.
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Targeting T Cell Co-receptors for Cancer Therapy.
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Baseline Biomarkers for Outcome of Melanoma Patients Treated with Pembrolizumab.
Clinical cancer research : an official journal of the American Association for Cancer Research.
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RECIST 1.1-Update and clarification: From the RECIST committee.
European journal of cancer.
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Increases in Absolute Lymphocytes and Circulating CD4+ and CD8+ T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with Ipilimumab.
Clinical cancer research : an official journal of the American Association for Cancer Research.
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Timing of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy.
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Immunodynamics: a cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials.
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Science (New York, N.Y.).
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EBioMedicine.
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Clinical cancer research : an official journal of the American Association for Cancer Research.
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Clonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion.
Immunity.
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CCR 20th Anniversary Commentary: Immune-Related Response Criteria--Capturing Clinical Activity in Immuno-Oncology.
Clinical cancer research : an official journal of the American Association for Cancer Research.
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Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma.
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Phase I Clinical Trial of Ipilimumab in Pediatric Patients with Advanced Solid Tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
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The New England journal of medicine.
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Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
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Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial.
The Lancet. Oncology.
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Peripheral T cell receptor diversity is associated with clinical outcomes following ipilimumab treatment in metastatic melanoma.
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The New Era of Cancer Immunotherapy: Manipulating T-Cell Activity to Overcome Malignancy.
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Seminars in oncology.
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The New England journal of medicine.
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Genomic profile, smoking, and response to anti-PD-1 therapy in non-small cell lung carcinoma.
Molecular & cellular oncology.
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Clinical Activity of Ipilimumab in Acral Melanoma: A Retrospective Review.
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On being less tolerant: enhanced cancer immunosurveillance enabled by targeting checkpoints and agonists of T cell activation.
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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.
Science (New York, N.Y.).
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Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment.
International journal of radiation oncology, biology, physics.
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Five-year survival rates for treatment-naive patients with advanced melanoma who received ipilimumab plus dacarbazine in a phase III trial.
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Clinical cancer research : an official journal of the American Association for Cancer Research.
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Immune-priming of the tumor microenvironment by radiotherapy: rationale for combination with immunotherapy to improve anticancer efficacy.
American journal of clinical oncology.
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
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Survival follow-up and ipilimumab retreatment of patients with advanced melanoma who received ipilimumab in prior phase II studies.
Annals of oncology : official journal of the European Society for Medical Oncology.
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Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial.
Lancet (London, England).
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Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.
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Opportunistic infections in patients treated with immunotherapy for cancer.
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A phase 2 randomised study of ramucirumab (IMC-1121B) with or without dacarbazine in patients with metastatic melanoma.
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Combination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates.
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Times cited: 61 -
Improved endpoints for cancer immunotherapy trials.
Journal of the National Cancer Institute.
2010
Information Resource
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Times cited: 485 -
Immunologic response to xenogeneic gp100 DNA in melanoma patients: comparison of particle-mediated epidermal delivery with intramuscular injection.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2010
Academic Article
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Times cited: 47 -
Immune regulatory antibodies: are they the next advance?.
Cancer journal (Sudbury, Mass.).
2010
Information Resource
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Times cited: 25 -
WT1 peptide vaccinations induce CD4 and CD8 T cell immune responses in patients with mesothelioma and non-small cell lung cancer.
Cancer immunology, immunotherapy : CII.
2010
Academic Article
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Times cited: 109 -
Improved survival with ipilimumab in patients with metastatic melanoma.
The New England journal of medicine.
2010
Academic Article
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Times cited: 12544 -
Radiotherapy after surgical resection for head and neck mucosal melanoma.
American journal of clinical oncology.
2010
Academic Article
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Times cited: 45 -
Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2010
Academic Article
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Times cited: 391 -
Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation.
PloS one.
2010
Academic Article
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Times cited: 221 -
Targeting cytotoxic T-lymphocyte antigen 4 in immunotherapies for melanoma and other cancers.
Immunotherapy.
2010
Information Resource
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Times cited: 20 -
Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia.
Blood.
2010
Academic Article
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Times cited: 134 -
Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: lymphocyte count after 2 doses correlates with survival.
Cancer.
2010
Academic Article
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Times cited: 386 -
Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs.
Blood.
2010
Academic Article
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Times cited: 102 -
Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study.
Annals of oncology : official journal of the European Society for Medical Oncology.
2010
Academic Article
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Times cited: 406 -
Phase II trial of neoadjuvant temozolomide in resectable melanoma patients.
Annals of oncology : official journal of the European Society for Medical Oncology.
2010
Academic Article
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Times cited: 20 -
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study.
The Lancet. Oncology.
2009
Academic Article
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Times cited: 863 -
Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2009
Academic Article
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Times cited: 2264 -
Cutting Edge: OX40 agonists can drive regulatory T cell expansion if the cytokine milieu is right.
Journal of immunology (Baltimore, Md. : 1950).
2009
Academic Article
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Times cited: 134 -
Safety and immunogenicity of a human and mouse gp100 DNA vaccine in a phase I trial of patients with melanoma.
Cancer immunity.
2009
Academic Article
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Times cited: 80 -
OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis.
The Journal of experimental medicine.
2009
Academic Article
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Times cited: 183 -
Immune rejection of mouse tumors expressing mutated self.
Cancer research.
2009
Academic Article
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Times cited: 15 -
Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response.
The Journal of experimental medicine.
2009
Academic Article
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Times cited: 92 -
Direct economic burden of high-risk and metastatic melanoma in the elderly: evidence from the SEER-Medicare linked database.
Applied health economics and health policy.
2009
Academic Article
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Times cited: 17 -
Optimization and validation of a robust human T-cell culture method for monitoring phenotypic and polyfunctional antigen-specific CD4 and CD8 T-cell responses.
Cytotherapy.
2009
Academic Article
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Times cited: 33 -
Development of effective vaccines for old mice in a tumor model.
Vaccine.
2008
Academic Article
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Times cited: 6 -
Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2008
Academic Article
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Times cited: 173 -
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit.
Proceedings of the National Academy of Sciences of the United States of America.
2008
Academic Article
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Times cited: 303 -
Improved tumor immunity using anti-tyrosinase related protein-1 monoclonal antibody combined with DNA vaccines in murine melanoma.
Cancer research.
2008
Academic Article
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Times cited: 27 -
Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Blood.
2008
Academic Article
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Times cited: 24 -
Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma.
Molecular therapy : the journal of the American Society of Gene Therapy.
2008
Academic Article
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Times cited: 80 -
Phase II study of extended-dose temozolomide in patients with melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2008
Academic Article
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Times cited: 56 -
Rapid enlargement of a malignant melanoma in a child with vitiligo vulgaris after application of topical tacrolimus.
Archives of dermatology.
2008
Article
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Times cited: 7 -
Mechanisms of immunization against cancer using chimeric antigens.
Molecular therapy : the journal of the American Society of Gene Therapy.
2008
Academic Article
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Times cited: 13 -
Meeting report: fourth international congress of the Society for Melanoma Research.
Pigment cell & melanoma research.
2008
Conference Paper
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Times cited: 4 -
The mechanism of anti-CTLA-4 activity and the negative regulation of T-cell activation.
The oncologist.
2008
Information Resource
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Times cited: 161 -
Antibody and CD8+ T cell responses against HER2/neu required for tumor eradication after DNA immunization with a Flt-3 ligand fusion vaccine.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2007
Academic Article
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Times cited: 23 - Safety and immunogenicity of tyrosinase DNA vaccines in patients with melanoma. Molecular therapy : the journal of the American Society of Gene Therapy. 2007 Academic Article GET IT
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Stage-IV melanoma and pulmonary metastases: factors predictive of survival.
Annals of surgical oncology.
2007
Academic Article
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Times cited: 70 -
Immunological validation of the EpitOptimizer program for streamlined design of heteroclitic epitopes.
Vaccine.
2007
Academic Article
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Times cited: 21 -
Surgical management of melanoma of the gallbladder: a report of 13 cases and review of the literature.
American journal of surgery.
2007
Information Resource
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Times cited: 32 -
Current topics in melanoma.
Current opinion in oncology.
2007
Information Resource
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Times cited: 21 -
Adjuvanticity of plasmid DNA encoding cytokines fused to immunoglobulin Fc domains.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2006
Academic Article
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Times cited: 41 -
DNA immunization against tissue-restricted antigens enhances tumor immunity after allogeneic hemopoietic stem cell transplantation.
Journal of immunology (Baltimore, Md. : 1950).
2006
Academic Article
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Times cited: 16 -
DNA vaccines against cancer.
Hematology/oncology clinics of North America.
2006
Information Resource
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Times cited: 17 -
Phase II study of temozolomide plus pegylated interferon-alpha-2b for metastatic melanoma.
Cancer.
2006
Academic Article
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Times cited: 45 -
Is tumor immunity the same thing as autoimmunity? Implications for cancer immunotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2006
Editorial Article
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Times cited: 17 -
Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity.
Cancer research.
2006
Academic Article
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Times cited: 183 -
Vaccination with human tyrosinase DNA induces antibody responses in dogs with advanced melanoma.
Cancer immunity.
2006
Academic Article
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Times cited: 129 -
Optimization of a self antigen for presentation of multiple epitopes in cancer immunity.
The Journal of clinical investigation.
2006
Academic Article
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Times cited: 82 - Can we use monoclonal antibodies to help T cells fight tumors?. Cytotherapy. 2006 Article GET IT
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In vitro expansion of Ag-specific T cells by HLA-A*0201-transfected K562 cells for immune monitoring.
Cytotherapy.
2006
Academic Article
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Times cited: 10 -
Unraveling the complex relationship between cancer immunity and autoimmunity: lessons from melanoma and vitiligo.
Advances in immunology.
2006
Information Resource
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Times cited: 54 -
Comparison of two cancer vaccines targeting tyrosinase: plasmid DNA and recombinant alphavirus replicon particles.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2005
Academic Article
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Times cited: 47 -
Dual mode reflectance and fluorescence confocal laser scanning microscopy for in vivo imaging melanoma progression in murine skin.
The Journal of investigative dermatology.
2005
Academic Article
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Times cited: 33 -
Induction of autoantibodies to syngeneic prostate-specific membrane antigen by xenogeneic vaccination.
International journal of cancer.
2005
Academic Article
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Times cited: 50 -
Development of a xenogeneic DNA vaccine program for canine malignant melanoma at the Animal Medical Center.
Vaccine.
2005
Academic Article
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Times cited: 197 -
Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study.
Cancer.
2005
Academic Article
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Times cited: 90 -
Antigens recognized by autologous antibodies of patients with soft tissue sarcoma.
Cancer immunity.
2005
Academic Article
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Times cited: 11 -
Identification of cancer-testis genes expressed by melanoma and soft tissue sarcoma using bioinformatics.
Cancer immunity.
2005
Academic Article
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Times cited: 34 -
CD8+ T-cell-dependent immunity following xenogeneic DNA immunization against CD20 in a tumor challenge model of B-cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2005
Academic Article
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Times cited: 29 -
DNA vaccines for melanoma.
Cancer chemotherapy and biological response modifiers.
2005
Information Resource
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Times cited: 3 - Persistence makes perfect: the benefits of IL-2 in adoptive immunotherapy. Cytotherapy. 2005 Article GET IT
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CD4 help and tumor immunity: beyond the activation of cytotoxic T lymphocytes.
Annals of surgical oncology.
2004
Editorial Article
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Times cited: 5 -
CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems.
Vaccine.
2004
Academic Article
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Times cited: 107 - Tumor antigens for cancer immunotherapy: therapeutic potential of xenogeneic DNA vaccines. Journal of translational medicine. 2004 Academic Article GET IT
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Selective CD4+ lymphopenia in melanoma patients treated with temozolomide: a toxicity with therapeutic implications.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2004
Academic Article
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Times cited: 206 -
Reassessing the usual suspects causing a commotion in the blood (and vessels?).
Cancer biology & therapy.
2004
Article
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Times cited: 1 -
Consistent antibody response against ganglioside GD2 induced in patients with melanoma by a GD2 lactone-keyhole limpet hemocyanin conjugate vaccine plus immunological adjuvant QS-21.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2003
Academic Article
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Times cited: 95 -
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2003
Academic Article
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Times cited: 134 -
Immunity to melanoma: unraveling the relation of tumor immunity and autoimmunity.
Oncogene.
2003
Information Resource
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Times cited: 76 -
A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen.
Journal of immunology (Baltimore, Md. : 1950).
2003
Academic Article
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Times cited: 90 -
Classification of clear-cell sarcoma as a subtype of melanoma by genomic profiling.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2003
Academic Article
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Times cited: 146 -
Long-term survival of dogs with advanced malignant melanoma after DNA vaccination with xenogeneic human tyrosinase: a phase I trial.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2003
Academic Article
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Times cited: 266 -
Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma.
Melanoma research.
2003
Academic Article
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Times cited: 29 -
The role of lipopolysaccharide in T-cell responses following DNA vaccination.
Vaccine.
2003
Academic Article
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Times cited: 7 -
How can we tell when cancer vaccines vaccinate?.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2003
Editorial Article
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Times cited: 8 - Immunity to cancer through immune recognition of altered self: studies with melanoma. Advances in cancer research. 2003 Information Resource GET IT
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Clinical results using biochemotherapy as a standard of care in advanced melanoma.
Melanoma research.
2002
Academic Article
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Times cited: 11 - Induction of autoantibodies against tyrosinase-related proteins following DNA vaccination: unexpected reactivity to a protein paralogue. Cancer immunity. 2002 Academic Article GET IT
- Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2002 Article GET IT
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GM-CSF DNA induces specific patterns of cytokines and chemokines in the skin: implications for DNA vaccines.
Cytokines, cellular & molecular therapy.
2002
Academic Article
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Times cited: 24 -
Melanoma vaccines.
Cancer investigation.
2002
Information Resource
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Times cited: 16 -
Alternative roles for interferon-gamma in the immune response to DNA vaccines encoding related melanosomal antigens.
Cancer immunity.
2001
Academic Article
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Times cited: 11 -
Vaccines for melanoma: translating basic immunology into new therapies.
The Lancet. Oncology.
2001
Information Resource
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Times cited: 41 -
Immunization with DNA coding for gp100 results in CD4 T-cell independent antitumor immunity.
Surgery.
2000
Academic Article
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Times cited: 83 -
Systemic chemotherapy.
Clinics in plastic surgery.
2000
Information Resource
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Times cited: 13 -
Management of renal cell carcinoma.
Oncology (Williston Park, N.Y.).
2000
Academic Article
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Times cited: 17 -
Coupling and uncoupling of tumor immunity and autoimmunity.
The Journal of experimental medicine.
1999
Academic Article
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Times cited: 216 -
Injection of DNA encoding granulocyte-macrophage colony-stimulating factor recruits dendritic cells for immune adjuvant effects.
Cytokines, cellular & molecular therapy.
1999
Academic Article
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Times cited: 54 -
Prophylactic recombinant epoetin alfa markedly reduces the need for blood transfusion in patients with metastatic melanoma treated with biochemotherapy.
Cytokines, cellular & molecular therapy.
1999
Academic Article
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Times cited: 8 -
Tumor immunity and autoimmunity induced by immunization with homologous DNA.
The Journal of clinical investigation.
1998
Academic Article
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Times cited: 203 - Treatment of Behçet disease with pentoxifylline. Annals of internal medicine. 1997 Article GET IT
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Melanocyte differentiation marker gp75, the brown locus protein, can be regulated independently of tyrosinase and pigmentation.
The Journal of investigative dermatology.
1995
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Activation of NF-kappa B may be necessary but is not sufficient for induction of H-2 antigens by TNF in J558L murine myeloma cells.
Journal of leukocyte biology.
1994
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Induction of HLA class I mRNA by cytokines in human fibroblasts: comparison of TNF, IL-1 and IFN-beta.
Cytokine.
1992
Academic Article
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Critical role of a common transcription factor, IRF-1, in the regulation of IFN-beta and IFN-inducible genes.
The EMBO journal.
1992
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There is more to hemorrhagic necrosis than tumor necrosis factor.
Journal of the National Cancer Institute.
1991
Editorial Article
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Times cited: 1