DNA vaccines against cancer. Review uri icon

Overview

abstract

  • Significant progress made in the field of tumor immunology by the characterization of a large number of tumor antigens, and the better understanding of the mechanisms preventing immune responses to malignancies has led to the extensive study of cancer immunization approaches such as DNA vaccines encoding tumor antigens. This article reviews major aspects of DNA immunization in cancer. It gives a brief history and then discusses the proposed mechanism of action, preclinical and clinical studies, and methods of enhancing the immune responses induced by DNA vaccines.

publication date

  • June 1, 2006

Research

keywords

  • Neoplasms
  • Vaccines, DNA

Identity

Scopus Document Identifier

  • 33746834535

PubMed ID

  • 16762727

Additional Document Info

volume

  • 20

issue

  • 3